Back to search

Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood–brain barrier

Data up to Jan 2025

Published2007
Citations58
References72

Total Citations Per Year

Abstract

References (72)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new mathematical model for relative quantification in real-time RT-PCR

2001 • 32,396 citations

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

1972 • 760 citations

Fatty acid import into mitochondria

2000 • 753 citations

Molecular and Functional Identification of Sodium Ion-dependent, High Affinity Human Carnitine Transporter OCTN2

1998 • 694 citations

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

1999 • 540 citations

Discovery of the ergothioneine transporter

2005 • 523 citations

Carnitine: a nutritional, biosynthetic, and functional perspective

2004 • 407 citations

Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

1997 • 377 citations

In vitro model for evaluating drug transport across the blood–brain barrier

1999 • 349 citations

cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter Family

1998 • 336 citations

Cloning and Functional Expression of a Human Na+and Cl−-dependent Neutral and Cationic Amino Acid Transporter B0+

1999 • 325 citations

Energy Contribution of Octanoate to Intact Rat Brain Metabolism Measured by13C Nuclear Magnetic Resonance Spectroscopy

2003 • 324 citations

Regulation of gamma‐glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells

1994 • 313 citations

Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: an electron microscopic immunogold study.

1991 • 312 citations

Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy.

2003 • 307 citations

Multiple Signaling Pathways Regulate Cell Surface Expression and Activity of the Excitatory Amino Acid Carrier 1 Subtype of Glu Transporter in C6 Glioma

1998 • 292 citations

Molecular and Functional Characterization of Organic Cation/Carnitine Transporter Family in Mice

2000 • 291 citations

B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system

1997 • 283 citations

Na+-dependent Glutamate Transporters (EAAT1, EAAT2, and EAAT3) of the Blood-Brain Barrier

1999 • 269 citations

P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

1997 • 249 citations

Molecular physiology of renal organic anion transporters

2006 • 237 citations

Long‐term acetyl‐L‐carnitine treatment in Alzheimer's disease

1991 • 233 citations

Bovine Brain Endothelial Cells Express Tight Junctions and Monoamine Oxidase Activity in Long‐Term Culture

1989 • 210 citations

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

2000 • 196 citations

Molecular Identification of a Novel Carnitine Transporter Specific to Human Testis

2002 • 190 citations

Rapid Report

2001 • 187 citations

GAT2/BGT-1 as a System Responsible for the Transport of γ-Aminobutyric Acid at the Mouse Blood–Brain Barrier

2001 • 167 citations

Rat Organic Anion Transporter 3 (rOAT3) is Responsible for Brain-to-Blood Efflux of Homovanillic Acid at the Abluminal Membrane of Brain Capillary Endothelial Cells

2003 • 160 citations

Cytoskeleton and Vesicle Mobility in Astrocytes

2006 • 157 citations

Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.

1998 • 157 citations

Functional relevance of carnitine transporter OCTN2 to brain distribution of<scp>l</scp>‐carnitine and acetyl‐<scp>l</scp>‐carnitine across the blood–brain barrier

2001 • 155 citations

Na+-coupled transport of l-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney

2001 • 148 citations

Utilization of Citrate, Acetylcarnitine, Acetate, Pyruvate and Glucose for the Synthesis of Acetylcholine in Rat Brain Slices

1981 • 140 citations

Carnitine transport: Pathophysiology and metabolism of known molecular defects

2003 • 136 citations

Molecular Cloning and Characterization of High-Affinity Carnitine Transporter from Rat Intestine

1998 • 102 citations

Molecular cloning and characterization of two novel transport proteins from rat kidney

1998 • 101 citations

Regulation of the Neuronal Glutamate Transporter Excitatory Amino Acid Carrier-1 (EAAC1) by Different Protein Kinase C Subtypes

2002 • 96 citations

Modulation of a Recombinant Glycine Transporter (GLYT1b) by Activation of Protein Kinase C

1995 • 96 citations

Carnitine, carnitine acyltransferases, and rat brain function

1982 • 92 citations

The carnitine acyltransferases: modulators of acyl-CoA-dependent reactions

2000 • 87 citations

Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells

2002 • 85 citations

Expression of CD83 Is Regulated by HuR via a Novel cis-Active Coding Region RNA Element

2006 • 81 citations

Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood-brain barrier during ischaemia

2002 • 79 citations

Localization of the Na + -d-glucose cotransporter SGLT1 in the blood-brain barrier

2004 • 78 citations

Inhibition of P-glycoprotein: rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier.

1998 • 77 citations

Phosphorylation of the Norepinephrine Transporter at Threonine 258 and Serine 259 Is Linked to Protein Kinase C-mediated Transporter Internalization

2006 • 76 citations

Polarized distribution of nucleoside transporters in rat brain endothelial and choroid plexus epithelial cells

2005 • 72 citations

ATA2 Is Predominantly Expressed as System A at the Blood-Brain Barrier and Acts as Brain-to-Blood Efflux Transport forl-Proline

2002 • 71 citations

Enhancement of l-Cystine Transport Activity and Its Relation to xCT Gene Induction at the Blood-Brain Barrier by Diethyl Maleate Treatment

2002 • 64 citations

In vivo post‐transcriptional regulation of GAP‐43 mRNA by overexpression of the RNA‐binding protein HuD

2006 • 59 citations

Differential excretion of xenobiotic acyl-esters of carnitine due to administration of pivampicillin and valproate

1990 • 55 citations

Study of the efficacy and tolerability of L-acetylcarnitine therapy in the senile brain.

1986 • 55 citations

Regulation by phorbol esters of the glycine transporter (GLYT1) in glioblastoma cells

1995 • 53 citations

Noradrenaline enhances monocarboxylate transporter 2 expression in cultured mouse cortical neurons via a translational regulation

2003 • 52 citations

Factor(s) released by glucose-deprived astrocytes enhance glucose transporter expression and activity in rat brain endothelial cells

2001 • 50 citations

Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes

2006 • 49 citations

Organic Cation/Carnitine Transporter, OCTN2, Is Differentially Expressed in the Adult Rat Epididymis1

2002 • 49 citations

Carnitine and glucuronic acid conjugates of pivalic acid

1985 • 42 citations

Effect of externally added carnitine on the synthesis of acetylcholine in rat cerebral cortex cells

1995 • 35 citations

Evidence for an Asymmetrical Uptake of L-Carnitine in the Blood-Brain Barrierin Vitro

1997 • 35 citations

Carnitine/xenobiotics transporters in the human mammary gland epithelia, MCF12A

2005 • 34 citations

Involvement of OCTN2 and B0,+ in the transport of carnitine through an in vitro model of the blood–brain barrier

2004 • 31 citations

The role of carnitine in the conjugation of acidic xenobiotics.

1986 • 29 citations

L-Carnitine transport in mouse renal and intestinal brush-border and basolateral membrane vesicles

2002 • 28 citations

Blood–Brain Barrier Controls Carnitine Level in the Brain: A Study on a Model System with RBE4 Cells

2000 • 26 citations

CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure

1998 • 25 citations

Membrane-Associated and Secreted Genes in Breast Cancer

2004 • 23 citations

Extraction, Partial Purification, and Reconstitution of a Mixture of Carriers from the Inner Mitochondrial Membrane

1986 • 12 citations

Accumulation of palmitoylcarnitine in neuroblastoma NB-2a cells affects the expression, phosphorylation and localization of B-50 protein

1998 • 12 citations

Transport of carnitine in RBE4 cells - an in vitro model of blood-brain barrier

1996 • 11 citations

Cited By (0)

Loading...
Localization of organic cation/carnitine transporter (OCTN2) in cells forming the… (2007) – Journal of Neurochemistry | Metascience Observatory Explorer