Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries.

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

Rhodopsin-like Protein from the Purple Membrane of Halobacterium halobium

1971 • 2,075 citations

Bacteriorhodopsin: a light-driven proton pump in Halobacterium Halobium

1975 • 994 citations

Bacteriorhodopsin and the purple membrane of halobacteria

1979 • 909 citations

Bacteriorhodopsin and Related Pigments of Halobacteria

1982 • 767 citations

Nobel lecture. The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.

1989 • 634 citations

Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212

1988 • 497 citations

Transmembrane Protein Structure: Spin Labeling of Bacteriorhodopsin Mutants

1990 • 465 citations

Role of aspartate-96 in proton translocation by bacteriorhodopsin.

1989 • 348 citations

Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.

1989 • 318 citations

Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: protein-cofactor (bacteriochlorophyll, bacteriopheophytin, and carotenoid) interactions.

1988 • 315 citations

A novel reversible thiol-specific spin label: Papain active site labeling and inhibition

1982 • 303 citations

Structure of the reaction center from Rhodobacter sphaeroides R-26: protein-cofactor (quinones and Fe2+) interactions.

1988 • 297 citations

Aspartic acid substitutions affect proton translocation by bacteriorhodopsin.

1988 • 282 citations

Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines

1989 • 263 citations

Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump.

1989 • 259 citations

Structural changes in bacteriorhodopsin during proton translocation revealed by neutron diffraction.

1989 • 258 citations

Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base.

1990 • 234 citations

Time-resolved X-ray diffraction study of structural changes associated with the photocycle of bacteriorhodopsin.

1991 • 213 citations

Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.

1989 • 203 citations

A defective proton pump, point-mutated bacteriorhodopsin Asp96----Asn is fully reactivated by azide.

1989 • 185 citations

Bacteriorhodopsin photoreaction: identification of a long-lived intermediate N (P, R350) at high pH and its M-like photoproduct

1988 • 154 citations

The role of back-reactions and proton uptake during the N .fwdarw. O transition in bacteriorhodopsin's photocycle: a kinetic resonance Raman study

1990 • 153 citations

Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation

1989 • 147 citations

Bacteriorhodopsin remains dispersed in fluid phospholipid bilayers over a wide range of bilayer thicknesses

1983 • 137 citations

Conformation of spin-labeled melittin at membrane surfaces investigated by pulse saturation recovery and continuous wave power saturation electron paramagnetic resonance

1989 • 130 citations

Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli.

1987 • 123 citations

Structure-Function Studies on Bacteriorhodopsin

1989 • 109 citations

Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid.

1980 • 100 citations

Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation.

1987 • 90 citations

Structure-function studies on bacteriorhodopsin. I. Expression of the bacterio-opsin gene in Escherichia coli.

1987 • 86 citations

Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin.

1989 • 84 citations

Structure-function studies on bacteriorhodopsin. III. Total synthesis of a gene for bacterio-opsin and its expression in Escherichia coli.

1987 • 84 citations

Infrared spectroscopic demonstration of a conformational change in bacteriorhodopsin involved in proton pumping.

1991 • 83 citations

The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates.

1991 • 57 citations

Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues

1989 • 39 citations