Toll-like receptors and other links between innate and acquired alloimmunity

Toll-like receptors and innate immunity

2001 • 4,138 citations

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

2004 • 3,766 citations

Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

2004 • 3,325 citations

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

2003 • 3,104 citations

Approaching the Asymptote? Evolution and Revolution in Immunology

1989 • 3,079 citations

Innate Immunity: The Virtues of a Nonclonal System of Recognition

1997 • 2,397 citations

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

2000 • 2,023 citations

Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

2002 • 1,877 citations

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex

2000 • 1,632 citations

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

2000 • 1,594 citations

Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2

2003 • 1,593 citations

Novel Signal Transduction Pathway Utilized by Extracellular HSP70

2002 • 1,483 citations

The immune response of Drosophila

2003 • 1,463 citations

Toll-like receptors control activation of adaptive immune responses

2001 • 1,374 citations

Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4

2002 • 1,339 citations

Toll-Like Receptor Signaling Pathways

2003 • 1,236 citations

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

2001 • 1,231 citations

Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling

2002 • 1,228 citations

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

2003 • 1,226 citations

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction

2003 • 1,203 citations

Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

2002 • 1,172 citations

Pattern Recognition Receptors

2002 • 1,139 citations

Drosophila innate immunity: an evolutionary perspective

2002 • 1,069 citations

TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway

2003 • 1,023 citations

A Toll-like Receptor That Prevents Infection by Uropathogenic Bacteria

2004 • 1,013 citations

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

2002 • 985 citations

TIRAP: an adapter molecule in the Toll signaling pathway

2001 • 962 citations

IRF3 Mediates a TLR3/TLR4-Specific Antiviral Gene Program

2002 • 844 citations

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

2002 • 803 citations

Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4

2002 • 648 citations

DC-SIGN Is the Major Mycobacterium tuberculosis Receptor on Human Dendritic Cells

2002 • 620 citations

Mammalian Toll-like receptors

2003 • 589 citations

Heat-shock proteins as activators of the innate immune system

2002 • 579 citations

Endotoxin-Induced Maturation of MyD88-Deficient Dendritic Cells

2001 • 505 citations

Local synthesis of complement component C3 regulates acute renal transplant rejection

2002 • 503 citations

Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity

2002 • 496 citations

The Toll–IL-1 receptor adaptor family grows to five members

2003 • 491 citations

The role of chemokines in linking innate and adaptive immunity

2002 • 487 citations

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

2003 • 450 citations

Cutting Edge: Activation of Toll-Like Receptor 2 Induces a Th2 Immune Response and Promotes Experimental Asthma

2004 • 448 citations

Toll-Like Receptor Ligands Directly Promote Activated CD4+ T Cell Survival

2004 • 389 citations

Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity

2002 • 384 citations

Flagellin Promotes Myeloid Differentiation Factor 88-Dependent Development of Th2-Type Response

2004 • 306 citations

Cutting Edge: The Immunostimulatory Activity of the Lung Surfactant Protein-A Involves Toll-Like Receptor 4

2002 • 306 citations

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

2003 • 305 citations

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

2003 • 261 citations

In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting

2002 • 258 citations

Toll-like receptors and T-helper-1/T-helper-2 responses

2003 • 203 citations

Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28−/− mice

2001 • 202 citations

The Role of Innate Immunity in Acute Allograft Rejection after Lung Transplantation

2003 • 178 citations

TH1 Immune Responses to Fully MHC Mismatched Allografts are Diminished in the Absence of MyD88, a Toll-Like Receptor Signal Adaptor Protein

2004 • 126 citations

Innate and Adaptive Immune Responses to Nonvascular Xenografts: Evidence That Macrophages Are Direct Effectors of Xenograft Rejection

2001 • 120 citations

Natural killer cells and their role in graft rejection

1998 • 90 citations

EVIDENCE THAT MACROPHAGES ARE REQUIRED FOR T-CELL INFILTRATION AND REJECTION OF FETAL PIG PANCREAS XENOGRAFTS IN NONOBESE DIABETIC MICE1

1998 • 74 citations

HEAT SHOCK PROTEINS, ANTI-HEAT SHOCK PROTEIN REACTIVITY AND ALLOGRAFT REJECTION

2001 • 68 citations

EARLY INCREASED CHEMOKINE EXPRESSION AND PRODUCTION IN MURINE ALLOGENEIC SKIN GRAFTS IS MEDIATED BY NATURAL KILLER CELLS1

2000 • 57 citations

C6 Produced by Macrophages Contributes to Cardiac Allograft Rejection

1999 • 56 citations

Toll-like receptor-4 and allograft responses

2004 • 35 citations