Genetic Heritability of Ischemic Stroke and the Contribution of Previously Reported Candidate Gene and Genomewide Associations
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Abstract
References (60)
Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.
1993 • 11,040 citations
GCTA: A Tool for Genome-wide Complex Trait Analysis
2010 • 6,938 citations
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
2008 • 2,860 citations
Genomewide Association Analysis of Coronary Artery Disease
2007 • 2,027 citations
Replication validity of genetic association studies
2001 • 1,845 citations
A comprehensive review of genetic association studies
2002 • 1,697 citations
A Simple Correction for Multiple Testing for Single-Nucleotide Polymorphisms in Linkage Disequilibrium with Each Other
2004 • 1,668 citations
A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction
2007 • 1,588 citations
Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
2005 • 1,361 citations
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
2009 • 1,083 citations
Variants conferring risk of atrial fibrillation on chromosome 4q25
2007 • 937 citations
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
2003 • 569 citations
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
2009 • 477 citations
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
2009 • 473 citations
Common variants in KCNN3 are associated with lone atrial fibrillation
2010 • 468 citations
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
2012 • 393 citations
Meta-analysis of Genetic Studies in Ischemic Stroke
2004 • 385 citations
Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke
2008 • 284 citations
Association of Polymorphisms in the CRP Gene With Circulating C-Reactive Protein Levels and Cardiovascular Events
2006 • 265 citations
A study of twins and stroke.
1992 • 254 citations
Genetic Liability in Stroke
2002 • 232 citations
Heritability and Genetic Correlations Explained by Common SNPs for Metabolic Syndrome Traits
2012 • 225 citations
Evaluating the Genetic Component of Ischemic Stroke Subtypes
2003 • 223 citations
Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke
2009 • 210 citations
A nonsynonymous SNP in PRKCH (protein kinase C η) increases the risk of cerebral infarction
2007 • 201 citations
Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain
2008 • 173 citations
Does Apolipoprotein E Genotype Influence the Risk of Ischemic Stroke, Intracerebral Hemorrhage, or Subarachnoid Hemorrhage?
2005 • 163 citations
Genetic Association Studies in Stroke
2005 • 140 citations
Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23
2010 • 136 citations
Tracking the Epidemiology of Human Genes in the Literature: The HuGE Published Literature Database
2006 • 130 citations
Causal Relationship of Susceptibility Genes to Ischemic Stroke: Comparison to Ischemic Heart Disease and Biochemical Determinants
2010 • 82 citations
Failure to Validate Association between 12p13 Variants and Ischemic Stroke
2010 • 81 citations
A Novel Loss-of-Function DDAH1 Promoter Polymorphism Is Associated With Increased Susceptibility to Thrombosis Stroke and Coronary Heart Disease
2010 • 78 citations
Paraoxonase 1 polymorphisms and ischemic stroke risk: A systematic review and meta-analysis
2010 • 63 citations
Genetic Variation in Members of the Leukotriene Biosynthesis Pathway Confer an Increased Risk of Ischemic Stroke
2008 • 56 citations
Association of a Genetic Variant in the <i>ALOX5AP</i> with Higher Risk of Ischemic Stroke: A Case-Control, Meta-Analysis and Functional Study
2010 • 55 citations
The 1425G/A SNP in PRKCH Is Associated With Ischemic Stroke and Cerebral Hemorrhage in a Chinese Population
2009 • 53 citations
A functional variant in the 3′-UTR of angiopoietin-1 might reduce stroke risk by interfering with the binding efficiency of microRNA 211
2010 • 52 citations
The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: Analysis in two Chinese populations
2009 • 52 citations
C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population
2009 • 48 citations
Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations
2010 • 47 citations
A genome-wide association study of carotid atherosclerosis in HIV-infected men
2010 • 46 citations
Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population
2010 • 44 citations
Apolipoprotein A5 Gene IVS3+G476A Allelic Variant Confers Susceptibility for Development of Ischemic Stroke
2008 • 44 citations
The PAI-1 4G/5G Gene Polymorphism and Ischemic Stroke: An Association Study and Meta-Analysis
2007 • 43 citations
Association of the −344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and stroke
2010 • 42 citations
Association of the C-399T promoter polymorphism of neuropeptide Y with susceptibility to ischemic stroke
2009 • 33 citations
Unravelling the Genetics of Ischaemic Stroke
2010 • 31 citations
Interaction of Genetic Risk Factors Confers Higher Risk for Thrombotic Stroke in Male Chinese: A Multicenter Case‐Control Study
2007 • 30 citations
Endothelial NO synthase gene polymorphisms and risk of ischemic stroke: A meta-analysis
2009 • 30 citations
Genetic variants in serum and glucocortocoid regulated kinase 1, a regulator of the epithelial sodium channel, are associated with ischaemic stroke
2011 • 30 citations
Association between the PDE4D gene and ischaemic stroke in the Chinese Han population
2009 • 28 citations
Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population
2010 • 27 citations
Functional Variants of Glucokinase Regulatory Protein and Apolipoprotein A5 Genes in Ischemic Stroke
2009 • 26 citations
Association of tumor necrosis factor-α and matrix metalloproteinase-3 gene variants with stroke
2011 • 22 citations
Age and sex dependent genetic effects of neuropeptide Y promoter polymorphism on susceptibility to ischemic stroke in Koreans
2010 • 18 citations
A meta-analysis of beta-fibrinogen gene-455G/A polymorphism and plasma fibrinogen level in Chinese cerebral infarction patients.
2007 • 16 citations
Genetic polymorphism of CYP11B2 gene and stroke intheHan Chinese population and a meta-analysis
2011 • 14 citations
Angiopoietin-2 promoter haplotypes confer an increased risk of stroke in a Chinese Han population
2009 • 9 citations
Failure to validate association between 12p13 variants and ischaemic stroke
2010 • 3 citations