Real-Time Visualization of a Fluorescent Gα_s: Dissociation of the Activated G Protein from Plasma Membrane

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Receptor-Mediated Activation of Heterotrimeric G-Proteins in Living Cells

2001 • 472 citations

Segregation of Heterotrimeric G Proteins in Cell Surface Microdomains

2001 • 370 citations

Activation and depalmitoylation of Gsα

1994 • 336 citations

Crystal Structure of the Adenylyl Cyclase Activator G _{s α}

1997 • 310 citations

XLαs is a new type of G protein

1994 • 223 citations

Internal Trafficking and Surface Mobility of a Functionally Intact β₂-Adrenergic Receptor-Green Fluorescent Protein Conjugate

1997 • 220 citations

Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity.

1992 • 205 citations

Light and electron microscopy

1993 • 202 citations

Involvement of a Heterotrimeric G Protein α Subunit in Tight Junction Biogenesis

1996 • 136 citations

Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling

1998 • 136 citations

Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.

1989 • 135 citations

Visualization of a Functional Gαq-Green Fluorescent Protein Fusion in Living Cells

2001 • 130 citations

Synthetic peptides as probes for G protein function. Carboxyl-terminal G alpha s peptides mimic Gs and evoke high affinity agonist binding to beta-adrenergic receptors.

1994 • 125 citations

Activation-induced subcellular redistribution of Gs alpha.

1996 • 125 citations

Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking

2000 • 114 citations

G Protein α Subunits Activate Tubulin GTPase and Modulate Microtubule Polymerization Dynamics

1999 • 109 citations

Tubulin, Gq, and Phosphatidylinositol 4,5-Bisphosphate Interact to Regulate Phospholipase Cβ1 Signaling

1997 • 90 citations

Persistent membrane association of activated and depalmitoylated G protein α subunits

1999 • 87 citations

G Protein β1γ2 Subunits Promote Microtubule Assembly

1997 • 86 citations

Cellular variations in heterotrimeric G protein localization and expression in rat pituitary.

1994 • 83 citations

Mutant G protein α subunit activated by Gβγ: A model for receptor activation?

2001 • 76 citations

Melatonin induction of filamentous structures in non-neuronal cells that is dependent on expression of the human mt1 melatonin receptor

2000 • 75 citations

Close association of the alpha subunits of Gq and G11 G proteins with actin filaments in WRK1 cells: relation to G protein-mediated phospholipase C activation.

1995 • 64 citations

Treatment of C6 Glioma Cells and Rats with Antidepressant Drugs Increases the Detergent Extraction of G_sα from Plasma Membrane

1999 • 53 citations

The subcellular localization of the G-protein Gi alpha in the basal ganglia reveals its potential role in both signal transduction and vesicle trafficking

1992 • 50 citations

Association of α_s-Subunit of the G_sProtein with Microfilaments and Microtubules: Implication during Adrenocorticotropin Stimulation in Rat Adrenal Glomerulosa Cells¹

1997 • 45 citations

The Stoichiometry of Gα_s Palmitoylation in Its Basal and Activated States

1997 • 43 citations

Muscarinic Receptor Activation Promotes the Membrane Association of Tubulin for the Regulation of Gq-Mediated Phospholipase Cβ₁Signaling

2000 • 42 citations

Visualization of distinct patterns of subcellular redistribution of the thyrotropin-releasing hormone receptor-1 and Gqα /G11α induced by agonist stimulation

1999 • 38 citations

Photoaffinity Identification of Colchicine‐Solubilized Regulatory Subunit from Rat Brain Adenylate Cyclase

1984 • 34 citations

Receptor-mediated activation of Gsalpha: evidence for intramolecular signal transduction.

1998 • 29 citations

A Proline-rich Region and Nearby Cysteine Residues Target XLαs to the Golgi Complex Region

2000 • 29 citations

Green fluorescent protein as a quantitative tool

2000 • 27 citations

Cellular variations in heterotrimeric G protein localization and expression in rat pituitary

1994 • 27 citations

Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling

1998 • 23 citations

Light and electron microscopic localization of α subunits of GTP-binding proteins, G0 and G1, in the cerebral cortex and hippocampus of rat brain

1992 • 19 citations

Association of s-Subunit of the Gs Protein with Microfilaments and Microtubules: Implication during Adrenocorticotropin Stimulation in Rat Adrenal Glomerulosa Cells

1997 • 19 citations

The decrease in the short variant of gsalpha protein is associated with an increase in [3H]CGP12177 binding, [3H]ouabain binding and Na, K-ATPase activity in brown adipose tissue plasma membranes of cold-acclimated hamsters

1999 • 5 citations