Anti-Vβ8 antibodies induce and maintain staphylococcal enterotoxin B-triggered Vβ8+ T cell anergy

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

Experimental Autoimmune Encephalomyelitis Induction in Genetically B Cell–deficient Mice

1996 • 665 citations

A maternally inherited superantigen encoded by a mammary tumour virus

1991 • 335 citations

Clonal expansion precedes anergy and death of V_β8⁺ peripheral T cells responding to staphylococcal enterotoxin B in vivo

1991 • 330 citations

Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice.

1990 • 312 citations

Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses.

1992 • 230 citations

Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen.

1993 • 184 citations

Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma.

1991 • 179 citations

Infection breaks T-cell tolerance

1992 • 174 citations

Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor.

1992 • 165 citations

Memory T cells are anergic to the superantigen staphylococcal enterotoxin B.

1992 • 92 citations

Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires.

1991 • 85 citations

A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1.

1989 • 75 citations

Secretion of T cell receptor fragments from recombinant Escherichia coli cells

1992 • 67 citations

B cells are not essential for peripheral T-cell tolerance.

1996 • 65 citations

The fate of anergic T cells in vivo.

1993 • 62 citations

B cell participation in the recursive selection of T cell repertoires

1988 • 57 citations

Specific modulation of T cells and murine experimental allergic encephalomyelitis by monoclonal anti-idiotypic antibodies.

1993 • 57 citations

Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor. Activation-induced cell death vs passive macrophage-dependent deletion.

1994 • 55 citations

Treatment of PL/J mice with the superantigen, staphylococcal enterotoxin B, prevents development of experimental allergic encephalomyelitis

1993 • 54 citations

Differential effects of superantigen‐induced “anergy” on priming and effector stages of a T cell‐dependent antibody response

1994 • 44 citations

Superantigen modulation of experimental allergic encephalomyelitis: activation of anergy determines outcome.

1994 • 41 citations

Mutual cell interactions and the selection of immune repertoires

1988 • 34 citations

T cells bearing the CD44hi “memory” phenotype display characteristics of activated cells in G1 stage of cell cycle

1992 • 31 citations

Immunoregulatory Effects of Superantigens: Interactions of Staphylococcal Enterotoxins with Host MHC and non‐MHC Products

1993 • 27 citations

Effects of staphylococcal enterotoxin B on T cell receptor Vβ utilization and clinical manifestations of experimental allergic encephalomyelitis

1993 • 23 citations

Superantigen-reactive T cells that display an anergic phenotype in vitro appear functional in vivo

1995 • 23 citations

Absence of peripheral clonal deletion and anergy in immune responses of T cell‐reconstituted athymic mice

1994 • 15 citations

Immunomodulation of Experimental Autoimmune Encephalomyelitis by Staphylococcal Enterotoxin D

1993 • 14 citations

Bacterial superantigens induce T cell unresponsiveness in B cell‐deficient mice

1995 • 12 citations

T Cell‐Dependent Antibody Response to Staphylococcal Enterotoxin B

1995 • 8 citations

Evidence for B cell participation in the in vitro and in vivo maintenance of in vivo staphylococcal enterotoxin B-induced T cell anergy

1997 • 7 citations

In Vivo Activation of T‐Cell Induction into the Primed Phenotype and Programmed Cell Death by Staphylococcal Enterotoxin B

1996 • 7 citations

Unresponsiveness to Mlsa induced in newborn Mlsb mice by maternal preimmunization.

1991 • 5 citations

Monoclonal antibodies to a TCR idiotope modulate the superantigen-induced responses of encephalitogenic rat T cells

1994 • 2 citations