A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

The nuclear lamina is a meshwork of intermediate-type filaments

1986 • 957 citations

Practice and Theory of Enzyme Immunoassays

1985 • 903 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

THE NUCLEAR ENVELOPE

1955 • 603 citations

Functional Organization Of The Nuclear Envelope

1988 • 593 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

The nuclear matrix: Three-dimensional architecture and protein composition

1982 • 445 citations

Core filaments of the nuclear matrix.

1990 • 436 citations

Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus

1986 • 436 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy.

1986 • 420 citations

Transcription occurs at a nucleoskeleton.

1985 • 303 citations

Light microscopic visualization of colloidal gold on resin-embedded tissue.

1983 • 298 citations

Identification of a novel nuclear domain.

1991 • 285 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Ultrastructural Pathology of the Cell and Matrix

1988 • 268 citations

The size of chromatin loops in HeLa cells.

1990 • 246 citations

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1991 • 243 citations

Replication occurs at a nucleoskeleton.

1986 • 230 citations

Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles.

1990 • 225 citations

The nuclear matrix: Structure and composition

1988 • 220 citations

Studies on Scaffold Attachment Sites and Their Relation to Genome Function

1990 • 210 citations

Localization of DNAase I-sensitive sequences to specific regions of interphase nuclei

1985 • 197 citations

Anti-RNP monoclonal antibodies derived from a mouse strain with lupus-like autoimmunity.

1982 • 192 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies.

1989 • 164 citations

Changes in distribution of nuclear matrix antigens during the mitotic cell cycle.

1984 • 159 citations

A subset of non-histone nuclear proteins reversibly stabilized by the sulfhydryl cross-linking reagent tetrathionate

1984 • 153 citations

The nuclear matrix from cells of different origin. Evidence for a common set of matrix proteins.

1990 • 151 citations

Preservation of specific RNA distribution within the chromatin-depleted nuclear substructure demonstrated by in situ hybridization coupled with biochemical fractionation.

1991 • 139 citations

The nuclear envelope

1989 • 122 citations

Localization of Nuclear Functions as Revealed by Ultrastructural Autoradiography and Cytochemistry

1974 • 119 citations

Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells.

1990 • 109 citations

Autoimmune sera recognize a 100 kD nuclear protein antigen (sp-100).

1987 • 105 citations

ORIGIN, DEVELOPMENT, AND NATURE OF INTRANUCLEAR RODLETS AND ASSOCIATED BODIES IN CHICKEN SYMPATHETIC NEURONS

1970 • 102 citations

Freeze Substitution and Low-Temperature Embedding

1992 • 98 citations

Distribution of the 70K U1 RNA-associated protein during interphase and mitosis: correlation with other U RNP particles and proteins of the nuclear matrix

1986 • 94 citations

INTRANUCLEAR FIBRILLAR BODIES IN ACTINOMYCIN D-TREATED OOCYTES

1969 • 92 citations

Comparison of antifading agents used in immunofluorescence

1989 • 86 citations

Nuclear Function and Organization: The Potential of Immunochemical Approaches

1988 • 79 citations

Autonomous splicing and complementation of in vivo-assembled spliceosomes.

1989 • 78 citations

High-resolution detection of newly synthesized DNA by anti-bromodeoxyuridine antibodies identifies specific chromatin domains.

1990 • 76 citations

Mature mRNA is selectively released from the nuclear matrix by an ATP/dATP-dependent mechanism sensitive to topoisomerase inhibitors.

1987 • 73 citations

Small nuclear RNA associated proteins: autoantigens in connective tissue diseases.

1989 • 65 citations

A microtubule-associated protein in the mitotic spindle and the interphase nucleus

1982 • 60 citations

Chromosomal Loop Organization in Eukaryotic Genomes

1990 • 59 citations

Nuclear substructure antigens

1986 • 53 citations

Evidence that a nuclear matrix protein participates in premessenger RNA splicing

1989 • 52 citations

Cytochalasin B selectively releases ovalbumin mRNA precursors but not the mature ovalbumin mRNA from hen oviduct nuclear matrix

1987 • 49 citations

Principles of nuclear organization

1990 • 47 citations

A widely distributed nuclear protein immunologically related to the microtubule-associated protein MAP1 is associated with the mitotic spindle.

1985 • 46 citations

Anti-nuclear antibodies of primary biliary cirrhosis recognize 78–92-kD and 96–100-kD proteins of nuclear bodies

1991 • 46 citations

Improved cryoprotection and freeze‐substitution of embryonic quail retina: A tem study on ultrastructural preservation

1990 • 43 citations

The nuclear matrix: current concepts and unanswered questions.

1986 • 40 citations

Computer Analysis of the Distribution of Nuclear Antigens: Studies on the Spatial and Functional Organization of the Interphase Nucleus

1986 • 34 citations

Nucleolar ribonucleoprotein release into the nucleoplasm as nuclear bodies in cultured thyrotropin-stimulated thyroid cells: Autoradiographic kinetics

1982 • 33 citations

Ultrastructural localization of nuclear matrix proteins in HeLa cells using silver-enhanced ultra-small gold probes.

1991 • 31 citations

High yields of specific hybridomas obtained by electrofusion of murine lymphocytes immunized in vivo or in vitro

1989 • 25 citations

Characterization of a family of nuclear and chromosomal proteins identified by a monoclonal antibody.

1985 • 21 citations

Nuclear bodies in mouse splenic lymphocytes: II ‐ Cytochemistry and autoradiography during stimulation by concanavalin A

1984 • 20 citations

Isolation and analysis of nuclear bodies from estrogen-stimulated chick liver

1989 • 19 citations

Nuclear Bodies as Functional Indicators in the Target Cells of Sex Steroid Hormones

1981 • 14 citations

Ausschleusung von Sphaeridien aus dem Zellkern

1969 • 12 citations

Functions of nuclear bodies as revealed by ultrastructural autoradiography and cytochemistry

1981 • 8 citations

Human autoantibodies identify a nuclear chromatin-associated antigen (PSL or p55) in human platelets.

1990 • 6 citations

Immunocytogenetics

1990 • 2 citations