Acute Induction of Adriamycin‐resistance in Human Colon Carcinoma HT‐29 Cells Exposed to a Sublethal Dose of Adriamycin

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGS

1989 • 1,799 citations

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

1981 • 1,463 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Stress proteins in biology and medicine

1990 • 731 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Synthesis and degradation of heat shock proteins during development and decay of thermotolerance.

1982 • 433 citations

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1984 • 398 citations

Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells.

1990 • 396 citations

Induction of Multidrug Resistance in Human Cells by Transient Exposure to Different Chemotherapeutic Drugs

1993 • 366 citations

Functional involvement of P-glycoprotein in blood-brain barrier.

1992 • 352 citations

MECHANISMS OF MULTIDRUG RESISTANCE AND IMPLICATIONS FOR THERAPY

1988 • 230 citations

Increased survival after treatments with anticancer agents of Chinese hamster cells expressing the human Mr 27,000 heat shock protein.

1991 • 227 citations

Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody.

1990 • 226 citations

The direct activation of human multidrug resistance gene (MDR1) by anticancer agents

1989 • 223 citations

Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts

1987 • 217 citations

Ethanol-induced tolerance to heat and to adriamycin

1978 • 201 citations

Coinduction of glucose-regulated proteins and doxorubicin resistance in Chinese hamster cells.

1987 • 191 citations

Oxidative injury and the heat shock response

1990 • 172 citations

A model for tumor cell killing by topoisomerase poisons.

1990 • 172 citations

Stress proteins in biology and medicine

1991 • 154 citations

Multidrug sensitivity phenotype of human lung cancer cells associated with topoisomerase II expression.

1992 • 138 citations

Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines.

1990 • 133 citations

Confluence‐dependent resistance in human colon cancer cells: Role of reduced drug accumulation and low intrinsic chemosensitivity of resting cells

1992 • 91 citations

Resistance to etoposide induced by three glucose-regulated stresses in Chinese hamster ovary cells.

1989 • 90 citations

A simple and fast method to extract RNA from tissue culture cells.

1990 • 88 citations

Mechanisms of resistance to drugs that inhibit DNA topoisomerases.

1991 • 72 citations

Genetic instability in the development of drug resistance.

1985 • 70 citations

An overview of membrane, cytosolic and nuclear proteins associated with the expression of resistance to multiple drugs in vitro

1992 • 58 citations

Depletion of topoisomerase II in isolated nuclei during a glucose-regulated stress response.

1989 • 57 citations

Mechanisms of resistance of confluent human and rat colon cancer cells to anthracyclines: alteration of drug passive diffusion.

1990 • 49 citations

DNA topoisomerase dysfunction: A new goal for antitumor chemotherapy

1990 • 47 citations

Heat shock proteins: role in thermotolerance, drug resistance, and relationship to DNA topoisomerases.

1987 • 46 citations

Bleomycin Induces the hsp 70 Heat Shock Promoter in Cultured Cells

1989 • 24 citations

Resistance mechanisms to topoisomerase poisons: the application of cell culture methods.

1992 • 14 citations