Mechanisms of resistance of confluent human and rat colon cancer cells to anthracyclines: alteration of drug passive diffusion.

New Human Tumor Cell Lines

1975 • 974 citations

Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia.

1979 • 454 citations

Potentiation of vincristine and Adriamycin effects in human hemopoietic tumor cell lines by calcium antagonists and calmodulin inhibitors.

1983 • 250 citations

Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells.

1988 • 244 citations

Mechanism of cross-resistance between vincristine and daunorubicin in Ehrlich ascites tumor cells.

1978 • 231 citations

Differential killing efficacy of twenty antitumor drugs on proliferating and nonproliferating human tumor cells.

1981 • 149 citations

Quantitative study of doxorubicin in living cell nuclei by microspectrofluorometry

1988 • 106 citations

Cellular transport of anthracyclines by passive diffusion

1985 • 102 citations

Aspects of cytotoxic drug penetration, with particular reference to anthracyclines

1987 • 91 citations

Cytotoxicity of adriamycin on aerobic and hypoxic chinese hamster V79 cells in vitro

1980 • 77 citations

Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.

1986 • 66 citations

Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or adriamycin.

1974 • 59 citations

Effect of different physiological conditions on the action of adriamycin on Chinese hamster cells in vitro

1981 • 53 citations

Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.

1977 • 52 citations

Tumoricidal effect of macrophages exposed to adriamycin in vivo or in vitro.

1982 • 52 citations

Cytofluorescence localization of adriamycin in resistant colon cancer cells

1984 • 44 citations

Effects of cell density on drug-induced cell kill kinetics in vitro (inoculum effect)

1986 • 43 citations

Mechanism of resistance of noncycling mammalian cells to 4'-(9-acridinylamino)methanesulfon-m-anisidide: comparison of uptake, metabolism, and DNA breakage in log- and plateau-phase Chinese hamster fibroblast cell cultures.

1988 • 31 citations

Mechanism of resistance of non-cycling mammalian cells to 4′-[9-acridinylamino]methanesulphon-m-anisidide: Role of DNA topoisomerase II in log- and plateau-phase CHO cells

1988 • 24 citations

Responses of proliferating and non-proliferating Chinese hamster cells to cytotoxic agents

1978 • 18 citations

A comparative study of the effects of anthracycline derivatives on a human adenocarcinoma cell line (LoVo) grown as a monolayer and as spheroids.

1988 • 10 citations