Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Presynaptic regulation of catecholamine release

1974 • 1,145 citations

Receptor activity and turnover of dopamine and noradrenaline after neuroleptics

1970 • 1,041 citations

The Rat Brain. A Stereotaxic Atlas

1964 • 1,002 citations

PRE AND POSTSYNAPTIC RECEPTORS

1976 • 778 citations

Comparison of Effects of L-Dopa, Amphetamine and Apomorphine on Firing Rate of Rat Dopaminergic Neurones

1973 • 436 citations

Evidence for a receptor-mediated feedback control of striatal tyrosine hydroxylase activity

1972 • 421 citations

Neuropsychopharmacology of monoamines and their regulatory enzymes.

1974 • 416 citations

Advances in Neurology. Vol. 2

1974 • 364 citations

Central dopaminergic neurons: Effects of alterations in impulse flow on the accumulation of dihydroxyphenylacetic acid

1976 • 363 citations

Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart

1972 • 293 citations

A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain

1972 • 273 citations

Frontiers in neurology and neuroscience research

1973 • 263 citations

Regulation of monoamine metabolism in the central nervous system.

1972 • 241 citations

Role of the α‐adrenoceptor in regulating noradrenaline overflow by nerve stimulation

1972 • 216 citations

Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway.

1973 • 209 citations

Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow.

1974 • 208 citations

Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine

1975 • 206 citations

The synaptic organization of the caudate nucleus

1971 • 199 citations

Effect of impulse flow on the release and synthesis of dopamine in the striatum

1973 • 174 citations

The role of presynaptic receptors in the release and synthesis of 3H-dopamine by slices of rat striatum

1976 • 166 citations

Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.

1968 • 164 citations

The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine).

1971 • 136 citations

Effect of flow‐stop on noradrenaline release from normal spleens and spleens treated with cocaine, phentolamine or phenoxybenzamine

1971 • 135 citations

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

1967 • 131 citations

The effect of acetylcholine upon mammalian motor nerve terminals.

1965 • 124 citations

EFFECT OF IMPULSE FLOW ON THE RELEASE AND SYNTHESIS OF DOPAMINE IN THE RAT STRIATUM

1973 • 110 citations

Alpha-receptor-mediated modulation of transmitter release from central noradrenergic neurones

1973 • 105 citations

Antagonistic effects of apomorphine and haloperidol on rat striatal synaptosomal tyrosine hydroxylase

1974 • 105 citations

Influence of ?-receptor stimulants on noradrenaline release

1971 • 104 citations

Dopaminergic neurons—Alteration in the kinetic properties of tyrosine hydroxylase after cessation of impulse flow

1976 • 97 citations

THE REGULATION OF TRANSMITTER RELEASE ELICITED BY NERVE STIMULATION THROUGH A PRESYNAPTIC FEED-BACK MECHANISM

1973 • 97 citations

Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity.

1975 • 89 citations

Dopamine neurons: role of impulse flow and presynaptic receptors in the regulation of tyrosine hydroxylase.

1975 • 81 citations

Dopaminergic neurons: effects of electrical stimulation on tyrosine hydroxylase.

1976 • 76 citations

Dopaminergic neurons—Alteration in the sensitivity of tyrosine hydroxylase to inhibition by endogenous dopamine after cessation of impulse flow

1976 • 61 citations

Electrophysiological effects of amphetamine on dopaminergic neurons

1973 • 60 citations

THE EFFECT OF ACETYLCHOLINE ON NEUROMUSCULAR TRANSMISSION IN THE FROG.

1963 • 58 citations

Release of noradrenaline and dopamine by nerve stimulation in the cat spleen perfused with ³H‐dopamine

1971 • 57 citations

The effect of dopamine and of apomorphine on dB-cAMP-induced stimulation of synaptosomal tyrosine hydroxylase

1974 • 47 citations

Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons.

1974 • 46 citations

The behavioral pharmacology of butaclamol hydrochloride (AY-23,028), a new potent neuroleptic drug

1975 • 36 citations

Molindone: a controlled evaluation in chronic schizophrenic patients.

1968 • 36 citations

Effects of chlorpromazine and three metabolites on behavioral responses in rats

1974 • 34 citations

Catecholamine release and receptors in brain slices

1973 • 30 citations

ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS

1973 • 30 citations

Interaction between indomethacin, oxymetazoline and phentolamine on the release of [3H]noradrenaline from brain slices

1973 • 23 citations

CATECHOLAMINE RELEASE AND RECEPTORS IN BRAIN SLICES

1973 • 21 citations

Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics.

1975 • 20 citations

Regulation of catecholamine release

1973 • 16 citations

The effects of clozapine, thioridazine and phenoxybenzamine on the action of drugs stimulating the central catecholamine receptors.

1974 • 13 citations

Butaclamol hydrochloride (AY-23,028): an early evaluation in severely ill schizophrenics.

1975 • 11 citations

REGULATION OF CATECHOLAMINE RELEASE

1973 • 10 citations

Inhibition of turning behaviour by clozapine in mice with unilateral destruction of dopaminergic nerve terminals

1975 • 9 citations

The influence of halothane on calcium uptake by isolated cell membranes

1973 • 7 citations