Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Principal components analysis corrects for stratification in genome-wide association studies

2006 • 9,771 citations

Global variation in copy number in the human genome

2006 • 4,228 citations

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

2007 • 1,750 citations

Structural Basis of Integrin Regulation and Signaling

2007 • 1,575 citations

STAT4and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus

2007 • 1,008 citations

Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

1990 • 886 citations

Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden

2006 • 812 citations

A revised estimate of twin concordance in systemic lupus erythematosus

1992 • 765 citations

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

2002 • 756 citations

Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 ng/mL or Lower

2005 • 677 citations

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus

2007 • 674 citations

Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE

2004 • 665 citations

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

2006 • 661 citations

Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus

2005 • 591 citations

An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus.

1997 • 497 citations

Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees

1998 • 458 citations

Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort

2005 • 403 citations

Complement deficiency and disease

1991 • 316 citations

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

2008 • 304 citations

Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.

1997 • 279 citations

Skewed distribution of IGG FC receptor iia (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients

1995 • 213 citations

Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE

2007 • 165 citations

Genetic linkage and association of Fcγ receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus

2002 • 143 citations

Systemic lupus erythematosus susceptibility loci defined by genome scan meta-analysis

2005 • 112 citations

The New York Cancer Project: Rationale, Organization, Design, and Baseline Characteristics

2004 • 92 citations

Meta-analysis of genome-wide linkage studies of systemic lupus erythematosus

2006 • 67 citations

Principal Component Analysis of Large Dispersion Matrices

1991 • 14 citations

Expression pattern and subcellular localization of five splice isoforms of human PXK.

2005 • 8 citations