Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Classical Electrostatics in Biology and Chemistry

1995 • 2,801 citations

Principles of protein-protein interactions.

1996 • 2,594 citations

A Hot Spot of Binding Energy in a Hormone-Receptor Interface

1995 • 1,943 citations

The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht

1999 • 1,932 citations

Anatomy of hot spots in protein interfaces

1998 • 1,908 citations

Shape complementarity at protein–protein interfaces

1994 • 1,217 citations

Diffusion-Controlled Macromolecular Interactions

1985 • 699 citations

Rapid, electrostatically assisted association of proteins

1996 • 562 citations

Homing endonucleases: keeping the house in order

1997 • 466 citations

Protein-DNA interactions: a structural analysis

1999 • 425 citations

[33] AMoRe: An automated molecular replacement program package

1997 • 365 citations

Protein-protein recognition: Crystal structural analysis of a barnase-barstar complex at 2.0-.ANG. resolution

1994 • 359 citations

Structural Features of Protein−Nucleic Acid Recognition Sites

1999 • 337 citations

Interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering

1993 • 283 citations

Electrostatic complementarity at protein/protein interfaces 1 1Edited by B. Honig

1997 • 251 citations

The biology of E colicins: paradigms and paradoxes

1996 • 239 citations

Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9 1 1Edited by A. R. Fersht

1999 • 235 citations

Wet and dry interfaces: the role of solvent in protein–protein and protein–DNA recognition

1999 • 217 citations

Mechanism of Ribonuclease Inhibition by Ribonuclease Inhibitor Protein Based on the Crystal Structure of its Complex with Ribonuclease A

1996 • 208 citations

The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein

1999 • 186 citations

Colicin Import intoEscherichia coliCells

1998 • 179 citations

Close encounters: why unstructured, polymeric domains can increase rates of specific macromolecular association

1993 • 177 citations

A Dataset of Protein–Protein Interfaces Generated with a Sequence-order-independent Comparison Technique

1996 • 168 citations

Structural and mechanistic basis of immunity toward endonuclease colicins.

1999 • 165 citations

Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition

1998 • 163 citations

Tight-binding inhibition of angiogenin and ribonuclease A by placental ribonuclease inhibitor

1989 • 163 citations

DNA-Protein: Structural Interactions

1995 • 155 citations

Protein-Protein Interactions in Colicin E9 DNase-Immunity Protein Complexes. 1. Diffusion-Controlled Association and Femtomolar Binding for the Cognate Complex

1995 • 142 citations

Structural principles governing domain motions in proteins

1999 • 135 citations

A Mutational Analysis of the Binding of Two Different Proteins to the Same Antibody

1996 • 131 citations

The Contribution of Contact and Non-contact Residues of Antibody in the Affinity of Binding to Antigen

1993 • 128 citations

Structural parsimony in endonuclease active sites: should the number of homing endonuclease families be redefined?

1999 • 110 citations

Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar

1993 • 106 citations

Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data

1992 • 101 citations

Protein-Protein Interactions in Colicin E9 DNase-Immunity Protein Complexes. 2. Cognate and Noncognate Interactions That Span the Millilmolar to Femptomolar Affinity Range

1995 • 88 citations

Immunity proteins and their specificity for endonuclease colicins: telling right from wrong in protein–protein recognition

1998 • 82 citations

Identification of Putative Active-site Residues in the DNase Domain of Colicin E9 by Random Mutagenesis

1996 • 80 citations

A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity

1998 • 77 citations

Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope

1997 • 76 citations

Homing in on the Role of Transition Metals in the HNH Motif of Colicin Endonucleases

1999 • 75 citations

Specificity in Protein−Protein Recognition: Conserved Im9 Residues Are the Major Determinants of Stability in the Colicin E9 DNase−Im9 Complex

1998 • 71 citations

Peptide binding by class I and class II MHC molecules

1997 • 70 citations

Three-Dimensional Solution Structure and ¹³C Nuclear Magnetic Resonance Assignments of the Colicin E9 Immunity Protein Im9^,

1996 • 59 citations

Dual Recognition and the Role of Specificity-Determining Residues in Colicin E9 DNase−Immunity Protein Interactions

1998 • 56 citations

Tandem overproduction and characterisation of the nuclease domain of colicin E9 and its cognate inhibitor protein Im9

1994 • 54 citations

The crystal structure of the immunity protein of colicin E7 suggests a possible colicin-interacting surface.

1996 • 52 citations

Protein-Protein Interaction Specificity of Im9 for the Endonuclease Toxin Colicin E9 Defined by Homologue-scanning Mutagenesis

1997 • 40 citations

Identification of critical residues in the colicin E9 DNase binding region of the Im9 protein

1997 • 27 citations

Investigation of the specificity of the interaction between colicin E9 and its immunity protein by site‐directed mutagenesis

1991 • 26 citations

NMR detection of slow conformational dynamics in an endonuclease toxin.

1998 • 26 citations

Slow conformational dynamics of an endonuclease persist in its complex with its natural protein inhibitor

2000 • 20 citations

Preliminary X-ray crystallographic analysis of the complex between the DNAase domain of colicin E9 and its cognate immunity protein

1999 • 6 citations