Specificity in Protein−Protein Recognition: Conserved Im9 Residues Are the Major Determinants of Stability in the Colicin E9 DNase−Im9 Complex

Interactions of protein antigens with antibodies.

1996 • 543 citations

Comparison of a Structural and a Functional Epitope

1993 • 512 citations

Antibody framework residues affecting the conformation of the hypervariable loops

1992 • 507 citations

Binding in the growth hormone receptor complex.

1996 • 434 citations

Principles of protein stability derived from protein engineering experiments

1993 • 262 citations

Elusive affinities

1995 • 145 citations

The Contribution of Contact and Non-contact Residues of Antibody in the Affinity of Binding to Antigen

1993 • 128 citations

Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data

1992 • 101 citations

Identification of Putative Active-site Residues in the DNase Domain of Colicin E9 by Random Mutagenesis

1996 • 80 citations

Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope

1997 • 76 citations

In vivo and in vitro characterization of overproduced colicin E9 immunity protein

1992 • 63 citations

Tandem overproduction and characterisation of the nuclease domain of colicin E9 and its cognate inhibitor protein Im9

1994 • 54 citations

Molecular analysis of the protein‐protein interaction between the E9 immunity protein and colicin E9

1992 • 29 citations

Identification of critical residues in the colicin E9 DNase binding region of the Im9 protein

1997 • 27 citations