Wet and dry interfaces: the role of solvent in protein–protein and protein–DNA recognition

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht

1999 • 1,932 citations

Anatomy of hot spots in protein interfaces

1998 • 1,908 citations

Crystal structure of trp represser/operator complex at atomic resolution

1988 • 899 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1974 • 548 citations

Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

1994 • 471 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1973 • 449 citations

Protein-DNA interactions: a structural analysis

1999 • 425 citations

Crystal structure at 1.7 Å of the bovine papillomavirus-1 E2 DMA-binding domain bound to its DNA target

1992 • 344 citations

Structural Features of Protein−Nucleic Acid Recognition Sites

1999 • 337 citations

Crystal structure of a human TATA box-binding protein/TATA element complex.

1996 • 281 citations

Crystal and molecular structures of the complex of α-chymotrypsin with its inhibitor Turkey ovomucoid third domain at 1.8 Å resolution

1987 • 215 citations

A Mutational Analysis of Binding Interactions in an Antigen−Antibody Protein−Protein Complex

1998 • 152 citations

Hydration and DNA Recognition by Homeodomains

1996 • 117 citations

Stability and specificity of protein-protein interactions: The case of the trypsin-trypsin inhibitor complexes

1976 • 113 citations

Structure of an Antibody–Lysozyme Complex Unexpected Effect of a Conservative Mutation

1995 • 87 citations

Water molecules participate in proteinase-inhibitor interactions: Crystal structures of Leu¹⁸, Ala¹⁸, and Gly¹⁸variants of turkey ovomucoid inhibitor third domain complexed withStreptomyces griseusproteinase B

1995 • 76 citations

Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope

1997 • 76 citations

The DNA target of the trp repressor.

1992 • 68 citations

Analysis of Binding Interactions in an Idiotope−Antiidiotope Protein−Protein Complex by Double Mutant Cycles

1997 • 67 citations

Hydration water molecules seen by NMR and by X-ray crystallography

1995 • 40 citations

Hydration of Biological Macromolecules in Solution: Surface Structure and Molecular Recognition

1993 • 20 citations