High-grade prostatic intraepithelial neoplasia

Cancer Statistics, 2001

2001 • 3,342 citations

Prostate cancer in a transgenic mouse.

1995 • 1,295 citations

The Frequency of Carcinoma and Intraepithelial Neoplasia of the Prostate in Young Male Patients

1993 • 748 citations

Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma

1998 • 638 citations

Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

1993 • 597 citations

Intraductal dysplasia: A premalignant lesion of the prostate

1986 • 584 citations

High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20-69: an autopsy study of 249 cases.

1994 • 573 citations

Prostatic Intra-Epithelial Neoplasia and Early Invasion in Prostate Cancer

1987 • 536 citations

Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer.

2002 • 478 citations

Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization.

1997 • 443 citations

PROSTATE CANCER DIAGNOSIS USING A SATURATION NEEDLE BIOPSY TECHNIQUE AFTER PREVIOUS NEGATIVE SEXTANT BIOPSIES

2001 • 421 citations

Androgen-independent prostate cancer progression in the TRAMP model.

1997 • 359 citations

Prostatic Intraepithelial Neoplasia is Risk Factor for Adenocarcinoma: Predictive Accuracy in Needle Biopsies

1995 • 313 citations

The American cancer society national prostate cancer detection project. Findings on the detection of early prostate cancer in 2425 men

1991 • 306 citations

Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia.

1995 • 289 citations

Spread of Adenocarcinoma Within Prostatic Ducts and Acini

1996 • 267 citations

Overexpression of the EphA2 tyrosine kinase in prostate cancer

1999 • 265 citations

Age and Racial Distribution of Prostatic Intraepithelial Neoplasia

1996 • 256 citations

The proliferative function of basal cells in the normal and hyperplastic human prostate

1994 • 251 citations

Architectural patterns of high-grade prostatic intraepithelial neoplasia

1993 • 251 citations

Human glandular kallikrein 2 (hK2) expression in prostatic intraepithelial neoplasia and adenocarcinoma: A novel prostate cancer marker

1997 • 237 citations

Estrogen Receptor Expression in Prostate Cancer and Premalignant Prostatic Lesions

1999 • 237 citations

Analysis of repeated biopsy results within 1 year after a noncancer diagnosis

2000 • 229 citations

Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization.

1995 • 225 citations

Repeat Prostate Needle Biopsy: Who Needs it?

1995 • 220 citations

Atypical adenomatous hyperplasia of the prostate: Morphologic criteria for its distinction from well-differentiated carcinoma

1993 • 219 citations

Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in the Human Prostate

2006 • 218 citations

OA-519 (fatty acid synthase) as an independent predictor of pathologic stage in adenocarcinoma of the prostate

1995 • 211 citations

Molecular biology of prostatic intraepithelial neoplasia

1996 • 207 citations

The Utility of Basal Cell—Specific Anti-Cytokeratin Antibody (34βE12) in the Diagnosis of Prostate Cancer

1995 • 204 citations

Predicting Cancer Following a Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia on Needle Biopsy

2001 • 196 citations

Independent origin of multiple foci of prostatic intraepithelial neoplasia

1998 • 196 citations

The extent and multicentricity of high-grade prostatic intraepithelial neoplasia in clinically localized prostatic adenocarcinoma

1997 • 187 citations

The Incidence of High Grade Prostatic Intraepithelial Neoplasia in Needle Biopsies

1995 • 177 citations

Prevalence and Predictors of a Positive Repeat Transrectal Ultrasound Guided Needle Biopsy of the Prostate

1997 • 175 citations

Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors.

2002 • 174 citations

The Relationship Between Prostatic Intraepithelial Neoplasia and Prostate Cancer: Critical Issues

1997 • 169 citations

Significance of prosttic intraepithelial neoplasia on prostate needle biopsy

1991 • 168 citations

Significance of high-grade prostatic intraepithelial neoplasia on needle biopsy

1993 • 168 citations

Prostatic intraepithelial neoplasia in mice expressing an androgen receptor transgene in prostate epithelium

2001 • 165 citations

Expression of p160erbB-3 and p185erbB-2 in Prostatic Intraepithelial Neoplasia and Prostatic Adenocarcinoma

1994 • 162 citations

Interobserver Reproducibility in the Diagnosis of Prostatic Intraepithelial Neoplasia

1995 • 152 citations

Effect of Neoadjuvant Endocrine Therapy (Combined Androgen Blockade) on Normal Prostate and Prostatic Carcinoma

1996 • 151 citations

The Focus of “Atypical Glands, Suspicious for Malignancy” in Prostatic Needle Biopsy Specimens:Incidence, Histologic Features, and Clinical Follow-Up of Cases Diagnosed in a Community Practice

1997 • 148 citations

Differential immunolocalization of estrogen receptor alpha and beta in rat ovary and uterus

1999 • 145 citations

Repeat Biopsy Strategy in Men with Isolated Prostatic Intraepithelial Neoplasia on Prostate Needle Biopsy

1996 • 134 citations

Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma.

1991 • 129 citations

PROSTATE CANCER DETECTION IN MEN WITH PRIOR HIGH GRADE PROSTATIC INTRAEPITHELIAL NEOPLASIA OR ATYPICAL PROSTATE BIOPSY

2001 • 126 citations

Epidemology of High Grade Prostatic Intraepithelial Neoplasia

1995 • 123 citations

Incidence of high-grade prostatic intraepithelial neoplasia in sextant needle biopsy specimens

1997 • 117 citations

Dysregulation of annexin I protein expression in high-grade prostatic intraepithelial neoplasia and prostate cancer.

2002 • 116 citations

Morphometric Analysis and Clinical Followup of Isolated Prostatic Intraepithelial Neoplasia in Needle Biopsy of the Prostate

1995 • 116 citations

Decrease of prostatic intraepithelialneoplasia following androgen deprivation therapy in patients with stage T3 carcinoma treated by radical prostatectomy

1994 • 114 citations

Ep-CAM LEVELS IN PROSTATIC ADENOCARCINOMA AND PROSTATIC INTRAEPITHELIAL NEOPLASIA

1999 • 111 citations

Prostatic intraepithelial neoplasia (PIN): Current concepts

1992 • 111 citations

A human prostatic epithelial model of hormonal carcinogenesis.

2001 • 109 citations

Detection of chromosomal anomalies and c-myc gene amplification in the cribriform pattern of prostatic intraepithelial neoplasia and carcinoma by fluorescence in situ hybridization.

1997 • 107 citations

Usefulness of immunoperoxidase staining with high-molecular-weight cytokeratin in the differential diagnosis of small-acinar lesions of the prostate gland

1990 • 104 citations

Atypical Basal Cell Hyperplasia of the Prostate

1993 • 103 citations

Incidental Prostatic Adenocarcinoma in Patients Undergoing Radical Cystoprostatectomy for Bladder Cancer

1996 • 102 citations

Prolactin Receptor Expression in the Developing Human Prostate and in Hyperplastic, Dysplastic, and Neoplastic Lesions

1999 • 100 citations

Workgroup 5: Assessment of prostate carcinoma in core needle biopsy--Definition of minimal criteria for the diagnosis of cancer in biopsy material

1996 • 99 citations

Does long-term finasteride therapy affect the histologic features of benign prostatic tissue and prostate cancer on needle biopsy?

1999 • 98 citations

Does Prostatic Ductal Adenocarcinoma Exist?

1999 • 95 citations

Atypical Basal Cell Hyperplasia of the Prostate

1992 • 95 citations

Strategy for Repeat Biopsy of Patients with Prostatic Intraepithelial Neoplasia Detected by Prostate Needle Biopsy

1996 • 93 citations

Loss of heterozygosity and tumor suppressor activity ofBin1 in prostate carcinoma

2000 • 91 citations

Expression of Bcl-2, Bax, and p53 in high-grade prostatic intraepithelial neoplasia and localized prostate cancer: relationship with apoptosis and proliferation

1998 • 91 citations

The significance of prostatic intra‐epithelial neoplasia

1995 • 90 citations

Rare Expression of High-Molecular-Weight Cytokeratin in Adenocarcinoma of the Prostate Gland

1999 • 89 citations

Use of transrectal ultrasound and prostate-specific antigen in diagnosis of prostatic intraepithelial neoplasia.

1989 • 87 citations

Evidence of multifocality of telomere erosion in high-grade prostatic intraepithelial neoplasia (HPIN) and concurrent carcinoma

2003 • 87 citations

SYSTEMATIC TRANSPERINEAL ULTRASOUND GUIDED TEMPLATE BIOPSY OF THE PROSTATE IN PATIENTS AT HIGH RISK

2001 • 86 citations

Does High Grade Prostatic Intraepithelial Neoplasia Result in Elevated Serum Prostate Specific Antigen levels?

1993 • 85 citations

Genetic pattern of prostate cancer progression

1999 • 85 citations

Keratin immunoreactivity as an aid to the diagnosis of persistent adenocarcinoma in irradiated human prostates

1989 • 84 citations

Histopathologic Effects of Three-Dimensional Conformal External Beam Radiation Therapy on Benign and Malignant Prostate Tissues

1999 • 83 citations

Histological markers of risk and the role of high-grade prostatic intraepithelial neoplasia

2001 • 82 citations

Prostatic Intraepithelial Neoplasia: Influence of Clinical and Pathological Data on the Detection of Prostate Cancer

1996 • 82 citations

Fibroblast growth factor 8 isoform B overexpression in prostate epithelium: a new mouse model for prostatic intraepithelial neoplasia.

2002 • 79 citations

Cell proliferation, apoptosis, oncogene, and tumor suppressor gene status in adenosis with comparison to benign prostatic hyperplasia, prostatic intraepithelial neoplasia, and cancer

1999 • 79 citations

Interphase cytogenetics of prostatic adenocarcinoma and precursor lesions: Analysis of 25 radical prostatectomies and 17 adjacent prostatic intraepithelial neoplasias

1995 • 79 citations

Effects of combination endocrine treatment on normal prostate, prostatic intraepithelial neoplasia, and prostatic adenocarcinoma.

1994 • 79 citations

Evaluation of prostate needle biopsies in a population-based screening study

1999 • 79 citations

Prostatic intraepithelial neoplasia is a risk factor for cancer.

1999 • 79 citations

TELOMERASE ACTIVITY, TELOMERE LENGTH, AND DNA PLOIDY IN PROSTATIC INTRAEPITHELIAL NEOPLASIA (PIN)

1998 • 78 citations

Interobserver variability in the diagnosis of high-grade prostatic intraepithelial neoplasia and adenocarcinoma.

1996 • 78 citations

The Extent and Zonal Location of Prostatic Intraepithelial Neoplasia and Atypical Adenomatous Hyperplasia: Relationship with Carcinoma in Radical Prostatectomy Specimens

1995 • 78 citations

Overexpression of the cell cycle inhibitor p16INK4A in high-grade prostatic intraepithelial neoplasia predicts early relapse in prostate cancer patients.

2001 • 76 citations

Prostatic intraepithelial neoplasia does not appear to raise serum prostate-specific antigen concentration

1996 • 76 citations

Cellular and Molecular Pathology of Prostate Cancer Precursors

2000 • 75 citations

Genetic and Chromosomal Alterations in Prostatic Intraepithelial Neoplasia and Carcinoma Detected by Fluorescence in situ Hybridization

1999 • 75 citations

Epidemiology of High-Grade Prostatic Intraepithelial Neoplasia

2000 • 74 citations

Progression of Prostatic Intraepithelial Neoplasia to Early Invasive Adenocarcinoma

1996 • 74 citations

Prostatic Intraepithelial Neoplasia: A Marker for High-Risk Groups and a Potential Target for Chemoprevention

1999 • 70 citations

Morphological identification of the patterns of prostatic intraepithelial neoplasia and their importance

2000 • 70 citations

Immunohistochemical Localization of Cyclooxygenase-1 and Cyclooxygenase-2 in the Human Fetal and Adult Male Reproductive Tracts¹

2000 • 70 citations

Expression of androgen receptor and growth factors in premalignant lesions of the prostate

1998 • 68 citations

Utilization of high molecular weight cytokeratin on prostate needle biopsies in an independent laboratory

1995 • 68 citations

Morphonuclear Relationship Between Prostatic Intraepithelial Neoplasia and Cancers as Assessed by Digital Cell Image Analysis

1991 • 67 citations

Genetic heterogeneity in a prostatic carcinoma and associated prostatic intraepithelial neoplasia as demonstrated by combined use of laser-microdissection, degenerate oligonucleotide primed PCR and comparative genomic hybridization

1998 • 67 citations

Effect of formalin fixation and epitope retrieval techniques on antibody 34betaE12 immunostaining of prostatic tissues.

1999 • 66 citations

Atypical Adenomatous Hyperplasia of the Prostate

1995 • 65 citations

Localization of epidermal growth factor receptor by immunohistochemical methods in human prostatic carcinoma, prostatic intraepithelial neoplasia, and benign hyperplasia.

1992 • 65 citations

P-Cadherin is a basal cell-specific epithelial marker that is not expressed in prostate cancer.

1997 • 63 citations

Antiestrogens and selective estrogen receptor modulators reduce prostate cancer risk

2003 • 63 citations

Analysis of cribriform morphology in prostatic neoplasia using antibody to high-molecular-weight cytokeratins.

1994 • 63 citations

Clinical significance of high-grade prostatic intraepithelial neoplasia in transurethral resection specimens

1997 • 63 citations

Prostatic intraepithelial neoplasia in dogs with spontaneous prostate cancer

1997 • 59 citations

Differential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma.

1997 • 59 citations

Overview of benign prostatic hypertrophy

1989 • 58 citations

Prostatic Intraepithelial Neoplasia Occurs Spontaneously in the Canine Prostate

1997 • 58 citations

Basal epithelial cells of human prostate gland are not myoepithelial cells. A comparative immunohistochemical and ultrastructural study with the human salivary gland.

1990 • 58 citations

Unusual Histologic Types of High-Grade Prostatic Intraepithelial Neoplasia

1997 • 57 citations

Analysis of the Capillary Architecture in the Precursors of Prostate Cancer: Recent Findings and New Concepts

1996 • 55 citations

Overdiagnosis of prostatic adenocarcinoma.

1999 • 54 citations

Diagnostic Uncertainty Expressed in Prostate Needle Biopsies

1999 • 54 citations

The canine prostate is a spontaneous model of intraepithelial neoplasia and prostate cancer progression.

1997 • 53 citations

Incidence and clinical significance of high-grade prostatic intraepithelial neoplasia in turp specimens

1997 • 53 citations

Diagnosis of Prostatic Intraepithelial Neoplasia: Prostate Working Group 1 Consensus Report

2000 • 52 citations

Selective estrogen receptor modulators for the chemoprevention of prostate cancer

2001 • 52 citations

Prostatic Intraepithelial Neoplasia and Invasive Carcinoma in Total Prostatectomy Specimens: Distribution, Volumes and DNA Ploidy

1993 • 51 citations

Workgroup 1: Origins of prostate cancer

1996 • 49 citations

p53 Alteration in regional lymph node metastases from prostate carcinoma

1999 • 48 citations

Progression-linked overexpression of c-Met in prostatic intraepithelial neoplasia and latent as well as clinical prostate cancers

1999 • 48 citations

High grade prostatic intraepithelial neoplasia in military working dogs with and without prostate cancer

1998 • 48 citations

Cytokeratin immunohistochemistry as a diagnostic tool for distinguishing malignant from benign epithelial lesions of the prostate.

1991 • 47 citations

Results of Rebiopsy for Suspected Prostate Cancer in Symptomatic Men with Elevated PSA Levels

1997 • 46 citations

DNA distribution in the prostate. Normal gland, benign and premalignant lesions, and subsequent adenocarcinomas.

1993 • 46 citations

QUANTITATIVE IMMUNOHISTOCHEMICAL ANALYSIS OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 IN HUMAN PROSTATIC ADENOCARCINOMA: A PROGNOSTIC STUDY

1998 • 46 citations

Do prostate specific antigen and prostate specific antigen density enhance the detection of prostate carcinoma after initial diagnosis of prostatic intraepithelial neoplasia without concurrent carcinoma?

1996 • 46 citations

EFFECT OF NEOADJUVANT HORMONAL THERAPY ON PROSTATIC INTRAEPITHELIAL NEOPLASIA AND ITS PROGNOSTIC SIGNIFICANCE

1999 • 45 citations

Pathology of premalignant lesions and carcinoma of the prostate in African-American men.

1998 • 45 citations

Prospective study of correlations between biopsy-detected high grade prostatic intraepithelial neoplasia, serum prostate specific antigen concentration, and race

2001 • 45 citations

Comparison of DNA ploidy in prostatic intraepithelial neoplasia and invasive carcinoma of the prostate: An image cytometric study

1994 • 45 citations

Measurement of cellular proliferation in human prostate by AgNOR, PCNA, and SPF

1993 • 45 citations

Predictors of prostate cancer on repeat transrectal ultrasound‐guided systematic prostate biopsy

2003 • 45 citations

Premalignant lesions of the prostate.

1988 • 44 citations

Bcl‐2 proto‐oncogene expression in low‐ and high‐grade prostatic intraepithelial neoplasia

2000 • 44 citations

Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis.

1999 • 43 citations

Quantitative analysis of prostatic intraepithelial neoplasia on tissue sections.

1990 • 42 citations

Use of Intervening Unstained Slides for Immunohistochemical Stains for High Molecular Weight Cytokeratin on Prostate Needle Biopsies

1999 • 42 citations

Prostatic intraepithelial neoplasia: Animal models 2000

2000 • 42 citations

Apoptotic Bodies in Prostatic Intraepithelial Neoplasia and Prostatic Adenocarcinoma Following Total Androgen Ablation

1995 • 41 citations

Diagnosis of Cowper's Glands on Prostate Needle Biopsy

1997 • 40 citations

Immunohistochemical expression of hepatocyte growth factor and c-Met/HGF receptor in benign and malignant human prostate tissue

2003 • 40 citations

The significance of atypical adenomatous hyperplasia and prostatic intraepithelial neoplasia for the development of prostate carcinoma

1995 • 40 citations

Clinical Prognostic Criteria for Later Diagnosis of Prostate Carcinoma in Patients with Initial Isolated Prostatic Intraepithelial Neoplasia

1996 • 39 citations

Cytokeratin 34βE-12 Immunoreactivity in Benign Prostatic Acini: Quantitation, Pattern Assessment, and Electron Microscopic Study

1999 • 39 citations

Effect of androgen deprivation therapy on prostatic intraepithelial neoplasia

2001 • 38 citations

Prostatic intraepithelial neoplasia in surgical resections

1997 • 38 citations

Nuclear changes in the normal-looking columnar epithelium adjacent to and distant from prostatic intraepithelial neoplasia and prostate cancer

2000 • 37 citations

Apoptosis in Prostatic Adenocarcinoma following Complete Androgen Ablation

1998 • 37 citations

Cell Kinetic Studies on Prostatic Intraepithelial Neoplasia (PIN) and Atypical Adenomatous Hyperplasia (AAH) of the Prostate

1995 • 36 citations

DNA quantitation of intraepithelial neoplasia and invasive carcinoma of the prostate

1993 • 36 citations

Occurrence of cell death (apoptosis) in prostatic intra-epithelial neoplasia

1993 • 35 citations

Immunohistochemical staining for DNA topoisomerase II-alpha in benign, premalignant, and malignant lesions of the prostate

2000 • 35 citations

Is prostatic intraepithelial neoplasia in the transition/central zone a true precursor of cancer? A long-term retrospective study in Norway

1998 • 34 citations

Transurethral Biopsy of the Prostate for Persistently Elevated or Increasing Prostate Specific Antigen Following Multiple Negative Transrectal Biopsies

1997 • 34 citations

Apolipoprotein‐D: A novel cellular marker for HGPIN and prostate cancer

2003 • 34 citations

Clinical Evolution of Prostatic Intraepithelial Neoplasia

1999 • 33 citations

Inverted (Hobnail) High-Grade Prostatic Intraepithelial Neoplasia (PIN)

2001 • 33 citations

Prostatic intraepithelial neoplasia (PIN) and other prostatic lesions as risk factors and surrogate endpoints for cancer chemoprevention trials

1996 • 33 citations

Distinguishing Cowper's Glands from Neoplastic and Pseudoneoplastic Lesions of Prostate

1997 • 33 citations

Prostate cancer screening: Role of digital rectal examination and prostate-specific antigen

1994 • 32 citations

High‐grade prostate intraepithelial neoplasia shares cytogenetic alterations with invasive prostate cancer

2001 • 31 citations

High-grade intra-epithelial neoplasia and prostate cancer in Dibombari, Cameroon

2003 • 31 citations

Reversibility of Prostatic Intraepithelial Neoplasia: Implications for Chemoprevention

1999 • 31 citations

Short term neoadjuvant androgen deprivation therapy does not affect prostate specific membrane antigen expression in prostate tissues

2000 • 31 citations

Relationship between atypical adenomatous hyperplasia (AAH), prostatic intraepithelial neoplasia (PIN) and prostatic adenocarcinoma.

1997 • 30 citations

Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium.

1999 • 30 citations

Computerized static DNA ploidy analysis of prostatic intraepithelial neoplasia.

1993 • 30 citations

Quantitative characterization of the frequency and location of cell proliferation and death in prostate pathology.

1994 • 30 citations

THE EFFECT OF HIGH GRADE PROSTATIC INTRAEPITHELIAL NEOPLASIA ON SERUM TOTAL AND PERCENTAGE OF FREE PROSTATE SPECIFIC ANTIGEN LEVELS

1999 • 30 citations

Determination of gene and chromosome dosage in prostatic intraepithelial neoplasia and carcinoma.

1998 • 30 citations

Human prostate-specific transglutaminase: a new prostatic marker with a unique distribution pattern.

1999 • 30 citations

Nucleolar and AgNOR-analysis of Prostatic Intraepithelial Neoplasia (PIN), Atypical Adenomatous Hyperplasia (AAH) and Prostatic Carcinoma

1995 • 30 citations

Tenascin-C expression in prostatic intraepithelial neoplasia (PIN): a marker of progression?

1998 • 29 citations

High Grade Prostatic Intraepithelial Neoplasia in Prostates Removed Following Irradiation Failure in the Treatment of Prostatic Adenocarcinoma

1995 • 28 citations

Persistence of high-grade prostatic intra-epithelial neoplasia under combined androgen blockade therapy

1999 • 28 citations

Potential Markers of Aggressiveness in Prostatic Intraepithelial Neoplasia Detected by Fluorescence in situ Hybridization

1996 • 28 citations

Genomic instability-based transgenic models of prostate cancer

2000 • 28 citations

Subtle changes in benign tissue adjacent to prostate neoplasia detected with a Bayesian belief network

1997 • 27 citations

Prevalence of prostatic intra-epithelial neoplasia (PIN) in biopsies from hospital practice and pilot screening: clinical implications

1997 • 27 citations

Precursors of Prostatic Cancer: Progression, Regression and Chemoprevention

1996 • 26 citations

Concordance of DNA content between prostatic intraepithelial neoplasia and concomitant invasive carcinoma. Evidence that prostatic intraepithelial neoplasia is a precursor of invasive prostatic carcinoma.

1993 • 26 citations

Prostatic Intraepithelial Neoplasia: A Lesion that May be Confused with Cancer on Prostatic Ultrasound

1989 • 25 citations

Genomic instability-based transgenic models of prostate cancer

2000 • 25 citations

Prostatic Intraepithelial Neoplasia: The Preinvasive Stage of Prostate Cancer: Overview of the Prostate Committee Report

2000 • 24 citations

High grade prostatic intraepithelial neoplasia is a disease

2001 • 24 citations

High-grade prostatic intraepithelial neoplasia and prostate cancer risk reduction

2003 • 23 citations

Evaluation of prostatic intraepithelial neoplasia after treatment with a 5-alpha-reductase inhibitor (finasteride). A methodologic approach.

1996 • 23 citations

TREATMENT CHANGES IN PROSTATIC HYPERPLASIA AND CANCER, INCLUDING ANDROGEN DEPRIVATION THERAPY AND RADIOTHERAPY

1999 • 22 citations

Aneuploidy and nuclear features of prostatic intraepithelial neoplasia (PIN)

1992 • 22 citations

High-Grade Prostatic Intraepithelial Neoplasia in Dogs

1999 • 22 citations

RER+ phenotype in prostate intra-epithelial neoplasia associated with human prostate-carcinoma development

1999 • 21 citations

Different patterns of p53 mutations in prostatic intraepithelial neoplasia and concurrent carcinoma: analysis of microdissected specimens.

1998 • 21 citations

Prostatic adenocarcinoma following androgen deprivation therapy: the new difficulty in histologic interpretation.

1998 • 19 citations

Incidence of prostatic intra-epithelial neoplasia in Osaka, Japan

1997 • 19 citations

Effect of High–Grade Prostatic Intraepithelial Neoplasia on Total and Percent Free Serum Prostatic–Specific Antigen

2000 • 19 citations

Repeat Biopsy Strategy in Men with Isolated Prostatic Intraepithelial Neoplasia on Prostate Needle Biopsy

1996 • 18 citations

Evolution of Isolated High-Grade Prostate Intraepithelial Neoplasia in a Mediterranean Patient Population

1999 • 18 citations

Telomerase activity modulation in the prevention of prostate cancer

2001 • 17 citations

Utility of Immunohistochemical Detection of High Molecular Weight Cytokeratin for Differential Diagnosis of Proliferative Conditions of the Prostate

1998 • 16 citations

Prostatic intraepithelial neoplasia: a potential precursor lesion of prostatic adenocarcinoma

1995 • 15 citations

Absence of S‐100 protein in prostatic glands

1988 • 15 citations

Biologic markers in prostatic intraepithelial neoplasia: immunohistochemical and cytogenetic analyses.

1999 • 14 citations

Decreased immunoexpression of prostate inhibin peptide in prostatic carcinoma: A study with monoclonal antibody

1999 • 14 citations

Glycoprotein A-80 in the human prostate: immunolocalization in prostatic intraepithelial neoplasia, carcinoma, radiation failure, and after neoadjuvant hormonal therapy

2003 • 14 citations

Ratio of Free to Total Prostate-Specific Antigen in Patients with Prostatic Intraepithelial Neoplasia

1998 • 14 citations

Influence of high‐grade prostatic intra‐epithelial neoplasia on total and percentage free serum prostatic specific antigen

1999 • 12 citations

Working Standards in Prostatic Intraepithelial Neoplasia and Atypical Adenomatous Hyperplasia

1995 • 12 citations

Precursor Lesions for Prostate Cancer

1997 • 12 citations

PIN I–III: When Should We Interfere?

1999 • 12 citations

Prostatic intraepithelial neoplasia: Significance and correlation with prostate-specific antigen and transrectal ultrasound: Editorial comment

1990 • 9 citations

[High-grade intraepithelial prostatic neoplasms: diagnosis and association with prostate cancer].

1996 • 8 citations

Preneoplastic lesions of the prostate-clinical, pathological and molecular biological aspects.

2002 • 7 citations

Follow-Up of Prostatic Intraepithelial Neoplasia

1996 • 7 citations

Preneoplastic lesions of the prostate.

1997 • 7 citations

Diagnosis of prostate carcinoma on biopsy specimens improved by basal-cell-specific anti-cytokeratin antibody (34 beta E12).

1998 • 7 citations

Precursors of Prostatic Adenocarcinoma: Recent Findings and New Concepts

1996 • 3 citations

[Influence of prostatic intraepithelial neoplasia on blood levels of PSA and free PSA percentage].

1999 • 2 citations

Deleted Work

1955 • 0 citations