Functions of netrins and semaphorins in axon guidance

CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS

1963 • 1,947 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

1995 • 687 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Mutations affecting growth cone guidance in drosophila: Genes necessary for guidance toward or away from the midline

1993 • 677 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes

1985 • 434 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Fasciclin IV: Sequence, expression, and function during growth cone guidance in the grasshopper embryo

1992 • 369 citations

Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans

1996 • 359 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons

1995 • 325 citations

Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation

1995 • 261 citations

commissureless Controls Growth Cone Guidance across the CNS Midline in Drosophila and Encodes a Novel Membrane Protein

1996 • 260 citations

Genes necessary for directed axonal elongation or fasciculation in C. elegans

1992 • 245 citations

Localized collapsing cues can steer growth cones without inducing their full collapse

1995 • 241 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

A family of molecules related to collapsin in the embryonic chick nervous system

1995 • 225 citations

Semaphorin II can function as a selective inhibitor of specific synaptic arborizations

1995 • 200 citations

Chemorepulsion of axons in the developing mammalian central nervous system

1993 • 180 citations

Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33.

1992 • 140 citations

Fasciclin III as a synaptic target recognition molecule in Drosophila

1995 • 134 citations

Ectopic expression of connectin reveals a repulsive function during growth cone guidance and synapse formation

1994 • 132 citations

Control of Topographic Retinal Axon Branching by Inhibitory Membrane-Bound Molecules

1994 • 122 citations

Guidance of cerebellofugal axons in the rat embryo: Directed growth toward the floor plate and subsequent elongation along the longitudinal axis

1995 • 100 citations

Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia

1993 • 99 citations

Chemorepulsion of developing motor axons by the floor plate

1995 • 98 citations

Targeted disruption of Ca2+-calmodulin signaling in Drosophila growth cones leads to stalls in axon extension and errors in axon guidance

1995 • 79 citations

Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain

1995 • 71 citations

Expression of a lacZ transgene reveals floor plate cell morphology and macromolecular transfer to commissural axons

1993 • 59 citations

EXAMINATION OF NEURONS IN WILD TYPE AND MUTANTS OFCAENORHABDITIS ELEGANSUSING ANTIBODIES TO HORSERADISH PEROXIDASE

2007 • 58 citations

The EGF Receptor Kinase Substrate p35 in the Floor Plate of the Embryonic Rat CNS

1989 • 57 citations

Examination of Neurons in Wild Type and Mutants of Caenorhabditis Elegans Using Antibodies to Horseradish Peroxidase

1991 • 50 citations