Production and characterization of monoclonal antibodies specific to multi‐ubiquitin chains of polyubiquitinated proteins

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

1983 • 1,105 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

1987 • 834 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis

1989 • 711 citations

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

The mechanism and functions of ATP‐dependent proteases in bacterial and animal cells

1992 • 450 citations

Lewy bodies are ubiquitinated

1988 • 392 citations

The immunochemical detection and quantitation of intracellular ubiquitin-protein conjugates.

1985 • 383 citations

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

1993 • 312 citations

Ubiquitin-lysozyme conjugates. Identification and characterization of an ATP-dependent protease from rabbit reticulocyte lysates.

1986 • 278 citations

Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

1985 • 263 citations

Identification of the long ubiquitin extension as ribosomal protein S27a

1989 • 240 citations

Natural substrates of the Ubiquitin proteolytic pathway

1991 • 238 citations

Activation-Induced Ubiquitination of the T Cell Antigen Receptor

1992 • 213 citations

Arthrin, a myofibrillar protein of insect flight muscle, is an actin-ubiquitin conjugate

1987 • 210 citations

The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes

1992 • 202 citations

Ligand-induced polyubiquitination of the platelet-derived growth factor beta-receptor.

1992 • 173 citations

Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock.

1987 • 145 citations

Ubiquitin in health and disease

1991 • 135 citations

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

1993 • 127 citations

Ubiquitin pathway involvement in human lymphocyte gamma-irradiation-induced apoptosis.

1993 • 124 citations

Effects of histone acetylation, ubiquitination and variants on nucleosome stability

1993 • 121 citations

Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors.

1993 • 119 citations

Ubiquitin-lysozyme conjugates. Purification and susceptibility to proteolysis.

1986 • 108 citations

Ubiquitin

1988 • 55 citations

[54] Radiolabeling of proteins

1990 • 43 citations

Subcellular distribution of ubiquitin–protein conjugates in the hippocampus following transient ischemia

1992 • 40 citations

Increase in ubiquitin conjugates dependent on ischemic damage

1993 • 39 citations

Active Transport of Iron by Intestine: Selective Genetic Defect in the Mouse

1970 • 30 citations

Different ratios in 20 S proteasomes and regulatory subunit complexes in two isoforms of the 26 S proteasome purified from rabbit skeletal muscle

1993 • 29 citations

Improved method for preparation of ubiquitin‐ligated lysozyme as substrate of ATP‐dependent proteolysis

1991 • 29 citations

Characterization of DNA synthesis at a restrictive temperature in the temperature-sensitive mutants, tsFT5 cells, that belong to the complementation group of ts85 cells containing a thermolabile ubiquitin-activating enzyme E1. Involvement of the ubiquitin-conjugating system in DNA replication

1993 • 19 citations