Effects of histone acetylation, ubiquitination and variants on nucleosome stability

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1993 • 1,116 citations

The histone core complex: an octamer assembled by two sets of protein-protein interactions

1978 • 357 citations

Use of selectively trypsinized nucleosome core particles to analyze the role of the histone “tails” in the stabilization of the nucleosome

1989 • 330 citations

A new procedure for purifying histone pairs H2A+H2B and H3+H4 from chromatin using hydroxylapatite

1979 • 327 citations

Structure of chromatin containing extensively acetylated H3 and H4

1978 • 290 citations

On the biological role of histone acetylation

1990 • 246 citations

Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes

1983 • 224 citations

A histone variant, H2AvD, is essential in Drosophila melanogaster.

1992 • 213 citations

Histone hyperacetylation: its effects on nucleosome conformation and stability

1986 • 211 citations

Nucleosomes: regulators of transcription

1990 • 186 citations

Nucleosome displacement in transcription

1993 • 179 citations

What happens to nucleosomes during transcription?

1992 • 169 citations

Crystallographic Structure of the Octameric Histone Core of the Nucleosome at a Resolution of 3.3 Å

1985 • 155 citations

Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcription

1990 • 153 citations

The structure and assembly of active chromatin

1990 • 133 citations

Histone acetylation alters the capacity of the H1 histones to condense transcriptionally active/competent chromatin.

1990 • 116 citations

Histone deacetylase is a component of the internal nuclear matrix.

1991 • 110 citations

Towards an understanding of the biological function of histone acetylation

1988 • 110 citations

Isolation and characterization of the histone variants in chicken erythrocytes

1979 • 102 citations

Chromatin structure and gene activity

1990 • 100 citations

Chicken erythrocyte polynucleosomes which are soluble at physiological ionic strength and contain linker histones are highly enriched hi β-globin gene sequences

1987 • 99 citations

H2A.F: an extremely variant histone H2A sequence expressed in the chicken embryo.

1983 • 88 citations

Structure of polyubiquitinated histone H2A

1989 • 82 citations

Drosophilahas a single copy of the gene encoding a highly conserved histone H2A variant of the H2A. F/Z type

1988 • 79 citations

Modulation of the Nucleosome Structure by Histone Acetylation

1980 • 76 citations

Differential dissociation of histone tails from core chromatin

1984 • 74 citations

Reversible and irreversible changes in nucleosome structure along the c-fos and c-myc oncogenes following inhibition of transcription

1990 • 74 citations

Fractionation and characterization of chromosomal proteins by the hydroxyapatite dissociation method.

1978 • 72 citations

Sequence of cDNAs for mammalian H2A.Z, an evolutionarily diverged but highly conserved basal histone H2A isoprotein species

1988 • 69 citations

Sequence and properties of the message encodingTetrahymenahv1, a highly evolutionarily conserved histone H2A variant that is associated with active genes

1988 • 66 citations

Changes in the histone H2A variant H2A.Z and polyubiquitinated histone species in developing trout testis

1987 • 64 citations

Two-dimensional gel systems for rapid histone analysis for use in minislab polyacrylamide gel electrophoresis

1982 • 60 citations

Chromatin structure of erythroid-specific genes of immature and mature chicken erythrocytes

1989 • 59 citations

Transcribed chromatin

1992 • 56 citations

Factors affecting nucleosome structure in transcriptionally active chromatin

1990 • 51 citations

The separation of transcriptionally engaged genes.

1988 • 51 citations

Interaction of RNA polymerase II with structurally altered nucleosomal particles

1989 • 50 citations

Nucleosomal histones of transcriptionally active/competent chromatin preferentially exchange with newly synthesized histones in quiescent chicken erythrocytes

1990 • 50 citations

Western blotting and immunochemical detection of histones electrophoretically resolved on acid-urea-Triton- and sodium dodecyl sulfate-polyacrylamide gels

1992 • 50 citations

Laser-induced crosslinking of histones to DNA in chromatin and core particles: implications in studying histone-DNA interactions

1989 • 49 citations

Ultrastructure of transcriptionally competent chromatin

1990 • 48 citations

H2a-specific proteolysis as a unique probe in the analysis of the histone octamer.

1988 • 47 citations

Distribution of methylated histones and histone methyltransferases in chicken erythrocyte chromatin

1989 • 39 citations

Structure and organization of the chicken H2B histone gene family

1987 • 34 citations

Minor Histone 2A Variants and Ubiquinated Forms in the Native H2A:H2B Dimer

1983 • 33 citations

Timing of the appearance of ubiquitinated histones in developing new macronuclei of Tetrahymena thermophila

1991 • 30 citations

Histone acetylation in chicken erythrocytes. Estimation of the percentage of sites actively modified

1986 • 23 citations

The occurrence of sperm isohistones H2B in single sea urchins

1981 • 18 citations

Enhanced stability of histone octamers from plant nucleosomes: Role of H2A and H2B histones

1992 • 15 citations

Effects of Histone Acetylation on Nucleosome Properties as Evaluated by Polyacrylamide Gel Electrophoresis and Hydroxylapatite Dissociation Chromatography1

1988 • 9 citations