GAL4 system in drosophila: A fly geneticist's swiss army knife

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Mosaic Analysis with a Repressible Cell Marker for Studies of Gene Function in Neuronal Morphogenesis

1999 • 2,521 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Reiterative Use of the EGF Receptor Triggers Differentiation of All Cell Types in the Drosophila Eye

1996 • 879 citations

TheDrosophilamushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells

1997 • 783 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

A conditional tissue-specific transgene expression system using inducible GAL4

2001 • 753 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Gal4 in the Drosophila female germline

1998 • 641 citations

Induction of Drosophila eye development by Decapentaplegic

1997 • 567 citations

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes.

1996 • 564 citations

GAL4 activates transcription in Drosophila

1988 • 521 citations

Systematic gain-of-function genetics in Drosophila

1998 • 467 citations

P{Switch}, a system for spatial and temporal control of gene expression in Drosophila melanogaster

2001 • 404 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

GAL4 activates gene expression in mammalian cells

1988 • 355 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps

2002 • 311 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

1997 • 273 citations

Ectopic Gene Expression inDrosophilaUsing GAL4 System

1998 • 262 citations

The Gene Search System: A Method for Efficient Detection and Rapid Molecular Identification of Genes in Drosophila melanogaster

1999 • 233 citations

GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of drosophila

1997 • 232 citations

Novel Genomic cDNA Hybrids Produce Effective RNA Interference in Adult Drosophila

2002 • 215 citations

Identifying loci required for follicular patterning using directed mosaics

1998 • 202 citations

Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

1994 • 182 citations

Yeast activators stimulate plant gene expression

1988 • 167 citations

RNAi Triggered by Symmetrically Transcribed Transgenes in Drosophila melanogaster

2002 • 150 citations

Primary structure of the Saccharomyces cerevisiae GAL4 gene.

1984 • 142 citations

Regulatory Circuits for Gene Expression: The Metabolism of Galactose and Phosphate

1982 • 141 citations

Investigating the function of follicular subpopulations during Drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation

2000 • 131 citations

In Vivo Functions of the Patched Protein

2000 • 128 citations

PPTGAL, a convenient Gal4 P‐element vector for testing expression of enhancer fragments in drosophila

2002 • 127 citations

Distinct expression patterns detected within individual tissues by the GAL4 enhancer trap technique

1996 • 121 citations

A Mutational Analysis of dishevelled in Drosophila Defines Novel Domains in the Dishevelled Protein as Well as Novel Suppressing Alleles of axin

2002 • 112 citations

Dual-Tagging Gene Trap of Novel Genes inDrosophila melanogaster

2001 • 112 citations

Efficient and heritable functional knock-out of an adult phenotype in Drosophila using a GAL4-driven hairpin RNA incorporating a heterologous spacer

2001 • 108 citations

Tetracycline-inducible systems for Drosophila

2001 • 95 citations

Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila

2002 • 63 citations

Creation of a GAL4/UAS‐coupled inducible gene expression system for use indrosophilacultured cell lines

2002 • 62 citations

Drosophila Mitotic Domain Boundaries as Cell Fate Boundaries

1997 • 62 citations

Targeted gene expression without a tissue-specific promoter: Creating mosaic embryos using laser-induced single-cell heat shock

1997 • 61 citations

A screen for genes expressed in Drosophila imaginal discs.

2002 • 48 citations

Identification of two proteins encoded by the Saccharomyces cerevisiae GAL4 gene.

1984 • 46 citations

Conditional expression of UAS‐transgenes in the adult eye with a new gene‐switch vector system

2002 • 45 citations

Homeotic transformation of legs to mouthparts by proboscipedia expression in Drosophila imaginal discs

1997 • 44 citations

Green fluorescent protein as a convenient and versatile marker for studies on functional genomics in Drosophila

2002 • 42 citations

Splice‐activated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in drosophila melanogaster

2002 • 40 citations

Adaptable doxycycline-regulated gene expression systems for Drosophila

2001 • 35 citations

Two‐color GFP imaging demonstrates cell‐autonomy of GAL4‐driven RNA interference in drosophila

2002 • 26 citations

A screen for dominant mutations applied to components in the Drosophila EGF-R pathway

2002 • 20 citations

Reverse genetics in drosophila: From sequence to phenotype using UAS‐RNAi transgenic flies

2002 • 16 citations

Probing for gene specificity in epithelial development.

1998 • 9 citations