Conserved 12-bp element downstream from mRNA polyadenylation sites

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA.

1983 • 1,555 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma

1983 • 732 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.

1986 • 559 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

1984 • 379 citations

The genome of human papovavirus BKV

1979 • 378 citations

A history of the human fetal globin gene duplication

1981 • 349 citations

Nucleotide sequences from the adenovirus-2 genome.

1982 • 345 citations

The evolution and sequence comparison of two recently diverged mouse chromosomal β-globin genes

1979 • 337 citations

Structure of mouse metallothionein-I gene and its mRNA

1981 • 301 citations

Sequence and organization of genes encoding the human 27 kDa heat shock protein

1986 • 299 citations

Comparison of Total Sequence of a Cloned Rabbit β-Globin Gene and Its Flanking Regions with a Homologous Mouse Sequence

1979 • 256 citations

Human papillomavirus 1a complete DNA sequence: a novel type of genome organization among papovaviridae.

1982 • 243 citations

Regulatory and coding potential of the mouse mammary tumor virus long terminal redundancy

1981 • 241 citations

Exon/intron organization and complete nucleotide sequence of an HLA gene.

1982 • 239 citations

Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C

1983 • 230 citations

The gene encoding the common alpha subunit of the four human glycoprotein hormones.

1981 • 225 citations

Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene.

1985 • 207 citations

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

1984 • 202 citations

The primary structure of the human ε-globin gene

1980 • 195 citations

Complete nucleotide sequence of the gene for human interleukin 1 alpha

1986 • 192 citations

Nucleotide sequence of the human N-myc gene.

1986 • 190 citations

Nucleotide sequence of the vaccinia virus thymidine kinase gene and the nature of spontaneous frameshift mutations

1983 • 179 citations

Characterization of the multigene family encoding the mouse S16 ribosomal protein: strategy for distinguishing an expressed gene from its processed pseudogene counterparts by an analysis of total genomic DNA.

1985 • 179 citations

DNA sequence of the rat growth hormone gene: location of the 5′ terminus of the growth hormone mRNA and identification of an internal transposon-like element

1981 • 161 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences

1985 • 152 citations

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.

1986 • 147 citations

Structure and expression of the murine N-myc gene.

1986 • 146 citations

Complete nucleotide sequence of the human δ-globin gene

1980 • 146 citations

A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.

1985 • 139 citations

A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro

1986 • 139 citations

An opsin gene expressed in only one photoreceptor cell type of the Drosophila eye

1986 • 134 citations

Structure of a chromosomal gene for human interferon β

1981 • 133 citations

Termination of transcription in the mouse α-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

1984 • 131 citations

Structure and gene organization in the transforming Hind III-G fragment of Ad12

1980 • 119 citations

The nucleotide sequence of the adult chicken alpha-globin genes.

1983 • 118 citations

Genes for Low-Molecular-Weight Heat Shock Proteins of Soybeans: Sequence Analysis of a Multigene Family

1985 • 114 citations

Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.

1985 • 105 citations

Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites.

1985 • 102 citations

Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster

1982 • 97 citations

RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro.

1985 • 95 citations

Cloning and structure of the human immune interferon-gamma chromosomal gene.

1982 • 92 citations

Myosin light-chain 1 and 3 gene has two structurally distinct and differentially regulated promoters evolving at different rates.

1985 • 85 citations

Expression of a mutant vasopressin gene: differential polyadenylation and read-through of the mRNA 3′ end in a frame-shift mutant.

1986 • 84 citations

Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene

1979 • 76 citations

Bovine leukemia virus: unique structural features of its long terminal repeats and its evolutionary relationship to human T-cell leukemia virus.

1984 • 72 citations

Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus.

1984 • 71 citations

RAD7 gene of Saccharomyces cerevisiae: transcripts, nucleotide sequence analysis, and functional relationship between the RAD7 and RAD23 gene products.

1986 • 71 citations

Characterization of the myosin light-chain-2 gene of Drosophila melanogaster.

1985 • 71 citations

Immediate-early mRNA-2 of herpes simplex viruses types 1 and 2 is unsplced: conserved sequences around the 5′ and 3′ termini correspond to transcription regulatory signals

1983 • 68 citations

The genes encoding the small subunit of ribulose-l,5-bisphosphate carboxylase are expressed differentially in petunia leaves

1986 • 67 citations

Genes for low-molecular-weight heat shock proteins of soybeans: sequence analysis of a multigene family.

1985 • 66 citations

Genetic engineering in the Precambrian: structure of the chicken triosephosphate isomerase gene.

1985 • 64 citations

Mutations downstream of the polyadenylation site of a Xenopus β-globin mRNA affect the position but not the efficiency of 3′ processing

1986 • 63 citations

Termination of the ovalbumin gene transcription.

1984 • 63 citations

Gene expression: The end of the message and beyond

1984 • 62 citations

Identification of sequences in the herpes simplex virus thymidine kinase gene required for efficient processing and polyadenylation.

1985 • 60 citations

Sequences involved in temperature and ecdysterone-induced transcription are located in separate regions of a Drosophila melanogaster heat shock gene.

1986 • 48 citations

Cell-specific expression of secreted versus membrane forms of immunoglobulin gamma 2b mRNA involves selective use of alternate polyadenylation sites.

1985 • 46 citations

Sequences near the 3′ Secretion-Specific Polyadenylation Site Influence Levels of Secretion-Specific and Membrane-Specific IgG2b mRNA in Myeloma Cells

1986 • 42 citations

Gene organization of the transforming region of adenovirus type 7 DNA

1982 • 37 citations

In vitro cleavage of the simian virus 40 early polyadenylation site adjacent to a required downstream TG sequence.

1986 • 36 citations

ATTAAA As Well As Downstream Sequences Are Required for RNA 3′-End Formation in the E3 Complex Transcription Unit of Adenovirus

1985 • 35 citations

DNA sequence of the 5′ flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus

1984 • 34 citations

Sequence signals which may be required for efficient formation of mRNA 3' termini

1986 • 30 citations

Requirement of A-A-U-A-A-A and adjacent downstream sequences for SV40 early potyadenylation

1986 • 30 citations

A 3′ co-terminus of two early herpes simplex virus type 1 mRNAs

1982 • 28 citations

Generation of Infectious Moloney Murine Leukemia Viruses with Deletions in the U3 Portion of the Long Terminal Repeat

1986 • 25 citations

Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.

1986 • 25 citations

Structural features of the murine dihydrofolate reductase transcription termination region: identification of a conserved DNA sequence element

1986 • 20 citations

ATTAAA as well as downstream sequences are required for RNA 3'-end formation in the E3 complex transcription unit of adenovirus.

1985 • 14 citations

Generation of infectious Moloney murine leukemia viruses with deletions in the U3 portion of the long terminal repeat.

1986 • 14 citations

The structure of HSAG-1, a middle repetitive genetic element which elicits a leukemia-related cellular surface antigen

1986 • 11 citations

Conserved elements in the 3′ untranslated regions of c-fos and actin mRNAs

1986 • 7 citations

Putative repressor binding sites in the regions mediating transcriptional control of viral and cellular genes

1985 • 3 citations

Asymmetry in the distributions of the four nucleotides at mRNA initiation and 3′ termini sites: Some geometrical implications

1987 • 2 citations