Binding of RU486 and deacylcortivazol to the glucocorticoid receptor is insensitive to sulfhydryl-modifying agents

Tissue sulfhydryl groups

1959 • 25,130 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Minimization of variation in the response to different proteins of the Coomassie blue G dye-binding assay for protein

1981 • 1,422 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Glucocorticoid receptors: Relations between steroid binding and biological effects

1972 • 554 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

1987 • 299 citations

Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis.

1978 • 258 citations

Adrenal Steroid Antagonism

1984 • 208 citations

Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells.

1981 • 190 citations

Domains of the Glucocorticoid Receptor Involved in Specific and Nonspecific Deoxyribonucleic Acid Binding, Hormone Activation, and Transcriptional Enhancement

1987 • 174 citations

RU 38486: An Original Multifaceted Antihormone in Vivo

1984 • 163 citations

Structure-activity relationships for glucocorticoids—I: Determination of receptor binding and biological activity

1977 • 147 citations

A Single Amino Acid That Determines the Sensitivity of Progesterone Receptors to RU486

1992 • 141 citations

Glucocorticoid- and progesterone-specific effects are determined by differential expression of the respective hormone receptors

1989 • 129 citations

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.

1987 • 125 citations

Identification of hormone-interacting amino acid residues within the steroid-binding domain of the glucocorticoid receptor in relation to other steroid hormone receptors.

1988 • 121 citations

Arsenite and cadmium(II) as probes of glucocorticoid receptor structure and function.

1990 • 118 citations

17α-Alkynyl-11β,17-dihydroxyandrostane derivatives : A new class of potent glucocorticoids.

1981 • 94 citations

The involvement of receptor sulphydryl groups in the binding of steroids to the cytoplasmic glucocorticoid receptor from rat thymus

1975 • 93 citations

Role of cysteines 640, 656, and 661 in steroid binding to rat glucocorticoid receptors.

1992 • 77 citations

Steroid Binding Activity Is Retained in a 16-kDa Fragment of the Steroid Binding Domain of Rat Glucocorticoid Receptors

1989 • 75 citations

Structurally based, selective interaction of arsenite with steroid receptors.

1990 • 75 citations

Anti-inflammatory pyrazolo-steroids: Potent glucocorticoids containing bulky a-ring substituents and no C3-carbonyl

1979 • 52 citations

17β- Carboxamide steroids are a new class of glucocorticoid antagonists

1979 • 51 citations

Steroid binding to hepatoma tissue culture cell glucocorticoid receptors involves at least two sulfhydryl groups.

1988 • 49 citations

A heat shock protein complex isolated from rabbit reticulocyte lysate can reconstitute a functional glucocorticoid receptor-Hsp90 complex

1992 • 49 citations

Screening of anti-progestagens by receptor studies and bioassays

1988 • 45 citations

Hydrogen peroxide stabilizes the steroid-binding state of rat liver glucocorticoid receptors by promoting disulfide bond formation

1988 • 41 citations

Effect of chemical inactivating agents on glucocorticoid receptor proteins in mouse and hamster cells.

1975 • 36 citations

Mammalian Progesterone Receptor Shows Differential Sensitivity to Sulfhydryl Group Modifying Agents When Bound to Agonist and Antagonist Ligands

1989 • 34 citations

Effect of Selenite on Glucocorticoid Receptor

1989 • 33 citations

Association of heat shock protein 90 with the 16 kDa steroid binding core fragment of rat glucocorticoid receptors

1991 • 28 citations

Synthesis of steroidal 17 β-carboxamide derivatives

1980 • 25 citations

Crystal Structure of Steroids: Molecular Conformation and Biological Function

1976 • 23 citations

Affinity-labeling steroids as biologically active probes of antiglucocorticoid hormone action

1986 • 23 citations

Inhibition of glucocorticoid receptor transformation, subunit dissociation, and temperature-dependent inactivation by various N-substituted maleimides

1988 • 17 citations

Inactivation of unbound rat liver glucocorticoid receptor by N-alkylmaleimides at sub-zero temperatures

1984 • 12 citations

ChemInform Abstract: The llß‐Substituted 19‐Norsteroids: at the Crossroads Between Hormone Agonists and Antagonists

1986 • 11 citations

Covalent chromatography by thiol-disulfide interchange of the highly-purified non-transformed rat liver glucocorticoid-receptor

1985 • 7 citations

[Hormones and antihormones. The steroidal model].

1991 • 4 citations

Steroid receptor exchange assay in the presence of acetonitrile: application to the study of glucocorticoid- and anti-ghicocorticoid-receptor complexes

1990 • 4 citations