The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

Caspases: Enemies Within

1998 • 6,923 citations

Caspases: killer proteases

1997 • 2,440 citations

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

1997 • 2,054 citations

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

1996 • 1,371 citations

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

1997 • 1,116 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis

1996 • 780 citations

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 • 616 citations

Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product

1995 • 604 citations

Human T Cell Leukemia Virus Type 1 Oncoprotein Tax Targets the Human Mitotic Checkpoint Protein MAD1

1998 • 528 citations

Target Protease Specificity of the Viral Serpin CrmA

1997 • 517 citations

The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.

1992 • 446 citations

Caspase-dependent Cleavage of Signaling Proteins during Apoptosis

1998 • 420 citations

The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein.

1990 • 417 citations

The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B.

1992 • 416 citations

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation.

1996 • 414 citations

Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.

1990 • 369 citations

Requirement of an ICE-Like Protease for Induction of Apoptosis and Ceramide Generation by REAPER

1996 • 262 citations

A20 zinc finger protein inhibits TNF and IL-1 signaling.

1996 • 250 citations

A20 Blocks Endothelial Cell Activation through a NF-κB-dependent Mechanism

1996 • 248 citations

Characterization of seven murine caspase family members

1997 • 207 citations

Activation of the B-cell Surface Receptor CD40 Induces A20, a Novel Zinc Finger Protein That Inhibits Apoptosis

1995 • 205 citations

Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair.

1990 • 190 citations

14-3-3 Proteins Associate with A20 in an Isoform-specific Manner and Function Both as Chaperone and Adapter Molecules

1996 • 181 citations

The cytokine‐inducible zinc finger protein A20 inhibits IL‐1‐induced NF‐κB activation at the level of TRAF6

1999 • 175 citations

Death substrates come alive

1997 • 167 citations

Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity.

1993 • 163 citations

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

1998 • 161 citations

Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment.

1995 • 154 citations

Cathepsin B-Mediated Activation of the Proinflammatory Caspase-11

1998 • 151 citations

Nuclear Factor kB-independent Cytoprotective Pathways Originating at Tumor Necrosis Factor Receptor-associated Factor 2

1998 • 104 citations

A Human Suppressor of c-Jun N-terminal Kinase 1 Activation by Tumor Necrosis Factor α

1997 • 102 citations

An interleukin‐1β‐converting enzyme‐like protease is a common mediator of apoptosis in thymocytes

1995 • 101 citations

CREB-2, a Cellular CRE-Dependent Transcription Repressor, Functions in Association with Tax as an Activator of the Human T-Cell Leukemia Virus Type 1 Promoter

1998 • 94 citations

Optimization of Experimental Variables Influencing Reporter Gene Expression in Hepatoma Cells Following Calcium Phosphate Transfection

1994 • 92 citations

Induction of Micronuclei by HTLV-I Tax: A Cellular Assay for Function

1993 • 89 citations

Nuclear c-Myc Plays an Important Role in the Cytotoxicity of Tumor Necrosis Factor Alpha in Tumor Cells

1994 • 89 citations

A Human T-cell Leukemia Virus Tax Variant Incapable of Activating NF-κB Retains Its Immortalizing Potential for Primary T-lymphocytes

1998 • 86 citations

Correlation between the anticellular and DNA fragmenting activities of tumor necrosis factor.

1988 • 78 citations

HTLV-I Tax self-association in optimal trans-activation function

1997 • 73 citations

Human T cell leukemia virus type I Tax and phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger protein by distinct mechanisms involving nuclear factor kappa B.

1993 • 72 citations

A20 Inhibits NF-κB Activation Independently of Binding to 14-3-3 Proteins

1997 • 45 citations

A20, an inhibitor of cell death, self‐associates by its zinc finger domain

1996 • 44 citations

Versatile, multi-featured plasmids for high-level expression of heterologous genes in Escherichia coli: overproduction of human and murine cytokines

1995 • 40 citations

Lipopolysaccharide-Induced NF-κB Activation in Human Endothelial Cells Involves Degradation of IκBα but Not IκBβ

1998 • 34 citations