Phosphorylation of the leucocyte NADPH oxidase subunit p47phox by casein kinase 2: conformation-dependent phosphorylation and modulation of oxidase activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Casein kinase 2: An ‘eminence grise’ in cellular regulation?

1990 • 920 citations

Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2

1991 • 669 citations

Human Leukemic Models of Myelomonocytic Development: A Review of the HL-60 and U937 Cell Lines

1985 • 649 citations

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.

1990 • 435 citations

Regulation of Human Leukocyte p21-Activated Kinases Through G Protein—Coupled Receptors

1995 • 415 citations

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

1991 • 379 citations

Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components.

1991 • 346 citations

The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases.

1994 • 342 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

NADPH Oxidase Activation and Assembly During Phagocytosis

1999 • 301 citations

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

1994 • 286 citations

Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.

1986 • 285 citations

NADPH oxidase of human neutrophils. Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system.

1987 • 266 citations

Casein kinases: pleiotropic mediators of cellular regulation

1993 • 264 citations

Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.

1990 • 248 citations

The Respiratory Burst Oxidase

1992 • 198 citations

The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis.

1995 • 184 citations

Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase.

1992 • 176 citations

Casein kinase II in signal transduction and cell cycle regulation

1993 • 170 citations

A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.

1986 • 168 citations

The cytosolic components of the respiratory burst oxidase exist as a M(r) approximately 240,000 complex that acquires a membrane-binding site during activation of the oxidase in a cell-free system.

1992 • 150 citations

Interactions between the Subunits of Casein Kinase II

1995 • 137 citations

Antagonists of Phosphatidylinositol 3-Kinase Block Activation of Several Novel Protein Kinases in Neutrophils

1995 • 127 citations

Ribofuranosyl‐benzimidazole derivatives as inhibitors of casein kinase‐2 and casein kinase‐1

1990 • 115 citations

Analysis of Activation-induced Conformational Changes in p47 Using Tryptophan Fluorescence Spectroscopy

1997 • 100 citations

Characterization of the catalytic subunit of casein kinase II expressed in Escherichia coli and regulation of activity.

1991 • 99 citations

Isolation of a Complex of Respiratory Burst Oxidase Components from Resting Neutrophil Cytosol

1994 • 96 citations

Kinetics of activation of casein kinase II by polyamines and reversal of 2,3-bisphosphoglycerate inhibition.

1984 • 95 citations

Protein phosphorylation and the respiratory burst

1988 • 82 citations

Kinase-dependent Activation of the Leukocyte NADPH Oxidase in a Cell-free System

1997 • 81 citations

Direct evidence for interaction between COOH-terminal regions of cytochrome b558 subunits and cytosolic 47-kDa protein during activation of an O(2-)-generating system in neutrophils.

1992 • 78 citations

Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation

1991 • 78 citations

Interactions between the components of the human NADPH oxidase A review about the intrigues in the phox family

1996 • 76 citations

Enhanced phosphorylation of the C-terminal domain of RNA polymerase II upon serum stimulation of quiescent cells: possible involvement of MAP kinases.

1994 • 74 citations

Characterization of the phosphotransferase domain of casein kinase II by site-directed mutagenesis and expression in Escherichia coli.

1992 • 65 citations

[11] Synthetic peptide substrates for casein kinase II

1991 • 60 citations

Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor

1994 • 54 citations

Receptor-mediated activation of multiple serine/threonine kinases in human leukocytes.

1993 • 51 citations

Dissociation of Mitogen-activated Protein Kinase Activation from the Oxidative Burst in Differentiated HL-60 Cells and Human Neutrophils

1995 • 48 citations

The Respiratory Burst Oxidase

1991 • 48 citations

Cell-free translocation of recombinant p47-phox, a component of the neutrophil NADPH oxidase: effects of guanosine 5'-O-(3-thiotriphosphate), diacylglycerol, and an anionic amphiphile

1992 • 43 citations

Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C.

1993 • 43 citations

Neutrophils stimulated with a chemotactic peptide or a phorbol ester exhibit different alterations in the activities of a battery of protein kinases.

1993 • 39 citations

Conformational changes of the leukocyte NADPH oxidase subunit p47phox during activation studied through its intrinsic fluorescence

1998 • 37 citations

Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system

2000 • 31 citations

Cytosolic factors in bovine neutrophil oxidase activation. Partial purification and demonstration of translocation to a membrane fraction

1990 • 31 citations

Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system

2000 • 26 citations

Intracellular Regulation: Rac and Bcr regulate phagocytic phoxes

1995 • 22 citations

Translocation of Recombinant p47phox Cytosolic Component of the Phagocyte Oxidase by in Vitro Phosphorylation

1995 • 21 citations

Characterization of Protein Interaction Among Subunits of Protein Kinase CKII In Vivo and In Vitro

1998 • 20 citations

Cytosolic Protein Phosphatase May Turn Off Activated NADPH Oxidase in Guinea Pig Neutrophils

1993 • 20 citations

Analysis of interactions between the subunits of protein kinase CK2

1996 • 17 citations

Purification and characterization of a lipid thiobis ester from human neutrophil cytosol that reversibly deactivates the O2- -generating NADPH oxidase.

1990 • 11 citations

Casein kinase II in signal transduction and cell cycle regulation

1993 • 9 citations