cAMP-dependent Protein Kinase-mediated Phosphorylation of Cystic Fibrosis Transmembrane Conductance Regulator Residue Ser-753 and Its Role in Channel Activation

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations

1991 • 1,036 citations

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

1992 • 937 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

1991 • 564 citations

Protein Phosphorylation and Neuronal Function

1985 • 525 citations

Nucleoside triphosphates are required to open the CFTR chloride channel

1991 • 520 citations

Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes

1991 • 498 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

1992 • 354 citations

Functional Modulation of Brain Sodium Channels by Protein Kinase C Phosphorylation

1991 • 325 citations

Phosphorylation of the cystic fibrosis transmembrane conductance regulator.

1992 • 324 citations

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

1993 • 296 citations

Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis.

1994 • 262 citations

Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity

1993 • 260 citations

A Phosphorylation Site in the Na ⁺ Channel Required for Modulation by Protein Kinase C

1991 • 252 citations

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by specific protein kinases and protein phosphatases.

1993 • 246 citations

Regulation by ATP and ADP of CFTR Chloride Channels That Contain Mutant Nucleotide-Binding Domains

1992 • 231 citations

Cystic fibrosis transmembrane conductance regulator: A chloride channel with novel regulation

1992 • 214 citations

Coupling of CFTR Cl− channel gating to an ATP hydrolysis cycle

1994 • 212 citations

Control of CFTR chloride conductance by ATP levels through non-hydrolytic binding

1992 • 167 citations

Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating.

1994 • 160 citations

Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.

1993 • 148 citations

Phosphorylation by cAMP-Dependent Protein Kinase Causes a Conformational Change in the R Domain of the Cystic Fibrosis Transmembrane Conductance Regulator

1994 • 114 citations

Functional roles of the nucleotide-binding folds in the activation of the cystic fibrosis transmembrane conductance regulator.

1993 • 92 citations

Regulation of CFTR Cl- conductance in secretion by cellular energy levels

1993 • 42 citations

Current Opinion in Nephrology and Hypertension

1998 • 25 citations

A Secretory Cl Channel from Epithelial Cells Studied in Heterologous Expression Systems

1994 • 8 citations