A DENDRITIC CELL LINE GENETICALLY MODIFIED TO EXPRESS CTLA4-IG AS A MEANS TO PROLONG ISLET ALLOGRAFT SURVIVAL12

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2021 • 6,783 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

1992 • 1,156 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

1993 • 502 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

COSTIMULATORY MOLECULE-DEFICIENT DENDRITIC CELL PROGENITORS (MHC CLASS II+, CD80dim, CD86-) PROLONG CARDIAC ALLOGRAFT SURVIVAL IN NONIMMUNOSUPPRESSED RECIPIENTS12

1996 • 378 citations

Interleukin 10 Secretion and Impaired Effector Function of Major Histocompatibility Complex Class II–restricted T Cells Anergized In Vivo

1998 • 225 citations

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer.

1992 • 224 citations

Maintenance of in Vivo Tolerance by Persistence of Antigen

1992 • 209 citations

Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival.

1995 • 202 citations

Dendritic cells process exogenous viral proteins and virus‐like particles for class I presentation to CD8⁺ cytotoxic T lymphocytes

1996 • 149 citations

Dendritic cells and tolerance induction

1996 • 128 citations

CTLA4Ig TREATMENT AMELIORATES THE LETHALITY OF MURINE GRAFT-VERSUS-HOST DISEASE ACROSS MAJOR HISTOCOMPATIBILITY COMPLEX BARRIERS

1994 • 123 citations

CTLA4-Ig PLUS BONE MARROW INDUCES LONG-TERM ALLOGRAFT SURVIVAL AND DONOR-SPECIFIC UNRESPONSIVENESS IN THE MURINE MODEL

1996 • 122 citations

Mechanisms of acquired thymic tolerance in experimental autoimmune encephalomyelitis: thymic dendritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo.

1995 • 121 citations

PHENOTYPE, FUNCTION, AND IN VIVO MIGRATION AND SURVIVAL OF ALLOGENEIC DENDRITIC CELL PROGENITORS GENETICALLY ENGINEERED TO EXPRESS TGF-??1,2

1998 • 108 citations

Dendritic cells: a major story unfolds

1995 • 97 citations

IMMUNOMODULATION OF PANCREATIC ISLET ALLOGRAFTS IN MICE WITH CTLA4Ig SECRETING MUSCLE CELLS

1995 • 67 citations

Retroviral immortalization of phagocytic and dendritic cell clones as a tool to investigate functional heterogeneity

1994 • 54 citations

PROLONGED SURVIVAL OF RAT ORTHOTOPIC LIVER ALLOGRAFTS AFTER INTRATHYMIC INOCULATION OF DONOR-STRAIN CELLS

1993 • 51 citations

Preventing allograft rejection with CTLA4IG: effect of donor-specific transfusion route or timing.

1996 • 19 citations

Bone marrow-derived macrophage lines and immortalized cloned macrophage and dendritic cells support priming of Borrelia burgdorferi — specific T cell responses in vitro and/or in vivo

1996 • 18 citations