Prognostic Significance of BCL-2 Expression in Localized Squamous Cell Carcinoma of the Head and Neck

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

1992 • 1,063 citations

Antigen unmasking on formalin‐fixed, paraffin‐embedded tissue sections

1993 • 733 citations

bcl-2 Protein in Non-Small-Cell Lung Carcinoma

1993 • 684 citations

Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

1993 • 597 citations

The Bcl-2 Protein: a Prognostic Indicator Strongly Related to p53 Protein in Lymph Node-Negative Breast Cancer Patients

1994 • 461 citations

Apoptosis (the 1992 Frank Rose Memorial Lecture)

1993 • 447 citations

BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy

1996 • 420 citations

Bcl-2 protein expression and long-term survival in breast cancer.

1994 • 404 citations

Ultrastructural localization of bcl-2 protein.

1992 • 351 citations

Multiple subcellular localization of bcl-2: detection in nuclear outer membrane, endoplasmic reticulum membrane, and mitochondrial membranes.

1994 • 290 citations

Expression of the bcl‐2 gene family in normal and malignant breast tissue: Low bax‐α expression in tumor cells correlates with resistance towards apoptosis

1995 • 242 citations

Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival

1994 • 164 citations

Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogenes.

1994 • 140 citations

bcl-2 protein expression correlates with recurrence and survival in early stage head and neck cancer treated by radiotherapy.

1996 • 92 citations

What is the value of bcl‐2 protein detection for histopathologists?

1995 • 59 citations