Improvement in Chronic Ischemic Neuropathy After Intramuscular phVEGF165 Gene Transfer in Patients With Critical Limb Ischemia

Tumor Angiogenesis: Therapeutic Implications

1971 • 9,898 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

1998 • 2,440 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.

1998 • 1,191 citations

Constitutive Expression of phVEGF ₁₆₅ After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia

1998 • 1,109 citations

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.

1994 • 1,058 citations

Gene Therapy for Myocardial Angiogenesis

1998 • 1,001 citations

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

1996 • 980 citations

Age-Dependent Impairment of Angiogenesis

1999 • 756 citations

Mouse model of angiogenesis.

1998 • 669 citations

Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.

1994 • 616 citations

Rescue of Diabetes-Related Impairment of Angiogenesis by Intramuscular Gene Therapy with Adeno-VEGF

1999 • 473 citations

Potentiated Angiogenic Effect of Scatter Factor/Hepatocyte Growth Factor via Induction of Vascular Endothelial Growth Factor

1998 • 443 citations

Direct Intramuscular Gene Transfer of Naked DNA Encoding Vascular Endothelial Growth Factor Augments Collateral Development and Tissue Perfusion

1996 • 396 citations

Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results

1998 • 390 citations

Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis

1995 • 330 citations

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

1998 • 320 citations

A 4, 2, and 1 stepping algorithm for quick and accurate estimation of cutaneous sensation threshold

1993 • 280 citations

Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo.

1996 • 215 citations

Coronary collateral development in swine after coronary artery occlusion.

1992 • 205 citations

Direct Intramuscular Injection of Plasmid DNA Encoding Angiopoietin-1 but not Angiopoietin-2 Augments Revascularization in the Rabbit Ischemic Hindlimb

1998 • 189 citations

Quantitative Sensory Testing

1994 • 166 citations

Arterial Gene Transfer for Therapeutic Angiogenesis in Patients with Peripheral Artery Disease. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts

1996 • 165 citations

Vibratory and cooling detection thresholds compared with other tests in diagnosing and staging diabetic neuropathy

1988 • 156 citations

Ischemic rnonornelic neuropathy

1983 • 147 citations

Clinical and pathological study of ischaemic neuropathy.

1967 • 135 citations

Quantitative sensory testing

1993 • 133 citations

Standards for evaluating and reporting the results of surgical and percutaneous therapy for peripheral arterial disease.

1991 • 121 citations

Polyneuropathy associated with monoclonal gammopathy of undetermined significance

1994 • 110 citations

Time course of increased cellular proliferation in collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency.

1995 • 109 citations

Endothelium-Dependent Relaxation of Collateral Microvessels After Intramuscular Gene Transfer of Vascular Endothelial Growth Factor in a Rat Model of Hindlimb Ischemia

1998 • 94 citations

Acute ischaemic neuropathy in the rabbit

1979 • 89 citations

Use of Synchrotron Radiation Microangiography to Assess Development of Small Collateral Arteries in a Rat Model of Hindlimb Ischemia

1997 • 82 citations

Peripheral Neuropathy Associated with Ischemic Vascular Disease of the Lower Limbs

1996 • 74 citations

Skeletal muscle and peripheral nerve changes caused by chronic arterial insufficiency--significance and clinical correlations--histological, histochemical and ultrastructural study.

1984 • 58 citations

Nerve and muscle vulnerability to ischemia

1985 • 58 citations

Heparin accelerates coronary collateral development in a porcine model of coronary artery occlusion.

1993 • 56 citations

Comparison of algorithms of testing for use in automated evaluation of sensation

1990 • 54 citations

Histochemical changes in striated muscle in patients with intermittent claudication.

1977 • 47 citations

Restoring lower limb blood flow improves conduction velocity in diabetic patients

1995 • 43 citations

ISCHAEMIC LESIONS OF PERIPHERAL NERVES: A REVIEW

1951 • 43 citations

Microangiographic assessment of collateral vessel formation following direct gene transfer of vascular endothelial growth factor in rats

1997 • 42 citations

AAEE case report #19: Ischemic monomelic neuropathy

1989 • 23 citations

The neuropathic factor in the aetiology of diabetic foot ulcers

1976 • 20 citations

The Digital Nerves and the Nerve Endings in Progressive Obliterative Vascular Disease of the Leg

1960 • 20 citations

Peripheral nerve conduction abnormalities in lower extremity ischemia: The effects of revascularization

1988 • 18 citations

Peripheral Neurological Complications of Aortoiliac Vascular Disease

1987 • 16 citations

Neuropathy in peripheral vascular disease; it bearing on diabetic neuropathy.

1956 • 15 citations