Reduction in susceptibility to natural killer cell-mediated lysis of human FO-1 melanoma cells after induction of HLA class I antigen expression by transfection with B2m gene.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

NK susceptibility varies inversely with target cell class I HLA antigen expression.

1987 • 433 citations

Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin.

1981 • 423 citations

The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit.

1987 • 320 citations

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

1991 • 304 citations

Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes.

1989 • 241 citations

Structure of wild-type and mutant mouse β2-microglobulin genes

1982 • 230 citations

Natural killer susceptibility of human cells may be regulated by genes in the HLA region on chromosome 6.

1986 • 141 citations

Level of HLA antigens in locoregional metastases and clinical course of the disease in patients with melanoma.

1988 • 136 citations

Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell‐mediated lysis is inversely correlated with HLA class I antigen expression

1989 • 133 citations

DR (Ia-like) antigens on human melanoma cells. Serological detection and immunochemical characterization.

1979 • 126 citations

Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent.

1980 • 120 citations

Purification of Murine IgG Monoclonal Antibodies by Precipitation with Caprylic Acid: Comparison with Other Methods of Purification

1989 • 120 citations

MHC antigens in human melanomas.

1991 • 111 citations

HETEROGENEOUS DISTRIBUTION OF THE DETERMINANTS DEFINED BY MONOCLONAL ANTIBODIES ON HLA-A AND B ANTIGENS BEARING MOLECULES

1982 • 111 citations

Increased resistance to non-MHC-restricted cytotoxicity related to HLA A, B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells.

1988 • 106 citations

Characterization of a monoclonal antibody-defined human melanoma-associated antigen susceptible to induction by immune interferon.

1987 • 101 citations

The alpha 1/alpha 2 domains of class I HLA molecules confer resistance to natural killing.

1989 • 95 citations

Regulatory role of a monomorphic determinant of HLA Class I antigens in T cell proliferation.

1985 • 81 citations

Induction of assembly of MHC class I heavy chains with beta 2microglobulin by interferon-gamma.

1989 • 72 citations

Susceptibility to Natural Killer Cell-Mediated Cytolysis Is Independent of the Level of Target Cell Class I HLA-A Expression1

2015 • 66 citations

Modulation by interferons of HLA antigen, high-molecular-weight melanoma associated antigen, and intercellular adhesion molecule 1 expression by cultured melanoma cells with different metastatic potential.

1989 • 64 citations

H-2 antigen expression and sensitivity of BL6 melanoma cells to natural killer cell cytotoxicity.

1988 • 60 citations

Transfection of beta 2-microglobulin restores IFN-mediated protection from natural killer cell lysis in YAC-1 lymphoma variants.

1990 • 60 citations

Association with beta 2-microglobulin controls the expression of transfected human class I genes.

1987 • 59 citations

HLA restriction of human cytotoxic T cells

1980 • 58 citations

The association between murine beta 2-microglobulin and HLA class I heavy chains results in serologically detectable conformational changes of both chains.

1985 • 55 citations

IFN-gamma treatment of K562 cells inhibits natural killer cell triggering and decreases the susceptibility to lysis by cytoplasmic granules from large granular lymphocytes.

1988 • 49 citations

High expression of the c-myc oncogene renders melanoma cells prone to lysis by natural killer cells.

1989 • 49 citations

Susceptibility to natural killer cell-mediated cytolysis is independent of the level of target cell class I HLA expression.

1989 • 49 citations

Natural killer susceptibility is independent of HLA class I antigen expression on cell lines obtained from human solid tumors

1990 • 46 citations

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells

1990 • 46 citations

Reconstitution of H‐2 class I expression by gene transfection decreases susceptibility to natural killer cells of an EL4 class I loss variant

1990 • 46 citations

NK sensitivity and lung clearance of MHC‐class‐I‐deficient cells within a heterogeneous fibrosarcoma

1989 • 44 citations

IFN-treated neuroblastoma cell lines remain resistant to T cell-mediated allo-killing, and susceptible to non-MHC-restricted cytotoxicity.

1988 • 43 citations

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells.

1989 • 40 citations

Studies of sublines selected for loss of HLA expression from an EBV-transformed lymphoblastoid cell line. Changes in sensitivity to cytotoxic T cells activated by allostimulation and natural killer cells activated by IFN or IL-2.

1989 • 40 citations

The monoclonal xenoantibody Q6/64 recognizes a determinant expressed by certain gene products of the A and B loci of the HLA region

1981 • 40 citations

Human beta 2-microglobulin specifically enhances cell-surface expression of HLA class I molecules in transfected murine cells.

1988 • 34 citations

Profile of intercellular adhesion molecule-1 (ICAM-1) synthesized by human melanoma cell lines.

1988 • 34 citations

Use of anti-HLA antibodies to mask major histocompatibility complex gene products on tumor cells can enhance susceptibility of these cells to lysis by natural killer cells.

1989 • 32 citations

In vitro differentiation and antigenic changes in human melanoma cell lines

1989 • 25 citations

Interferon-γ is a strong modulator of NK susceptibility and expression of β2-microglobulin but not of transferrin receptors of K562 cells

1985 • 25 citations

Class I (H-2Kb) gene transfection reduces susceptibility of YAC-1 lymphoma targets to natural killer cells

1990 • 20 citations

Distinct effects of interferon-γ and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis

1990 • 16 citations

Effect of IFN‐γ treatment and in vivo passage of murine tumor cell lines on their sensitivity to lymphokine‐activated killef (LAK) cell lysis in vitro; association with H‐2 expression on the target cells

1989 • 16 citations

Recombinant gamma interferon provokes resistance of human breast cancer cells to spontaneous and IL-2 activated non-MHC restricted cytotoxicity

1990 • 14 citations