HLA restriction of human cytotoxic T cells

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

ANKYLOSING SPONDYLITIS AND HL-A 27

1973 • 1,801 citations

HISTOCOMPATIBILITY TESTING, 1972

1974 • 1,267 citations

Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis.

1968 • 1,214 citations

Biology of the Mouse Histocompatibility-2 Complex

1975 • 1,145 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

1974 • 832 citations

Histocompatibility Testing, 1975

1976 • 736 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus

1978 • 528 citations

Evolutionary Significance of the HL-A System

1972 • 523 citations

The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

1975 • 479 citations

In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice.

1975 • 454 citations

The Major Histocompatibility Complex of the Mouse

1979 • 423 citations

Specificity of Virus‐Immune Effector T Cells for H‐2K or H‐2D Compatible Interactions: Implications for H‐Antigen Diversity

1976 • 385 citations

The Immune Response Genes of the Major Histocompatibility Complex

1978 • 382 citations

Cytotoxic effector cells specific for B Cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis.

1975 • 368 citations

Y-antigen killing by T cells of women is restricted by HLA

1977 • 326 citations

Long‐term T‐cell‐mediated immunity to epstein‐barr virus in man. I. Complete regression of virus‐induced transformation in cultures of seropositive donor leukocytes

1978 • 294 citations

Generation of both cross-reactive and virus-specific T-cell populations after immunization with serologically distinct influenza A viruses.

1977 • 285 citations

HLA restriction of cell-mediated lysis of influenza virus-infected human cells

1977 • 274 citations

Functional Specificity of Thymus-Dependent Lymphocytes

1977 • 256 citations

EVOLUTION AND FUNCTION OF THE HLA SYSTEM

1978 • 234 citations

Cytotoxic T cells kill influenza virus infected cells but do not distinguish between serologically distinct type A viruses

1977 • 229 citations

Responsiveness to HY Antigen Ir Gene Complementation and Target Cell Specificity

1977 • 215 citations

THYMIC ORIGIN OF ATYPICAL LYMPHOID CELLS IN INFECTIOUS MONONUCLEOSIS

1973 • 212 citations

Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for Semliki Forest virus.

1978 • 210 citations

Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype.

1978 • 166 citations

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness.

1978 • 166 citations

Immunologic recognition of influenza virus-infected cells

1977 • 158 citations

Macrophage‐Dependent Response of Immune Human T Lymphocytes to PPD In Vitro Influence of HLA‐D Histocompatibility

1977 • 146 citations

Establishment of Cell Lines from Peripheral Leucocytes in Infectious Mononucleosis

1967 • 137 citations

The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region

1979 • 134 citations

Purification and structural characterisation of human HLA-linked B-cell antigens

1977 • 129 citations

Murine Ia and human DR antigens: homology of amino-terminal sequences.

1978 • 125 citations

Cell-Mediated Immunity to Epstein–Barr-Virus-Transformed Lymphoblastoid Cells in Acute Infectious Mononucleosis

1975 • 125 citations

Organization of the Immune Response Genes

1979 • 125 citations

Immunologic recognition of influenza virus-infected cells. II. Expression of influenza A matrix protein on the infected cell surface and its role in recognition by cross-reactive cytotoxic T cells

1977 • 118 citations

Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.

1975 • 115 citations

Long‐term T‐cell‐mediated immunity to Epstein‐Barr virus in man. III. Activation of cytotoxic T cells in virus‐infected leukocyte cultures

1979 • 114 citations

Influenza virus‐specific cytotoxic T cells in man; induction and properties of the cytotoxic cell

1978 • 112 citations

H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice.

1976 • 107 citations

Association between an HLA haplotype and low responsiveness to tetanus toxoid in man

1978 • 107 citations

Human cell-mediated cytotoxicity against modified target cells is restricted by HLA

1977 • 103 citations

Specific in vitro antibody response to influenza virus by human blood lymphocytes

1979 • 99 citations

Long‐term T‐cell‐mediated immunity to Epstein‐Barr virus in man. II. Components necessary for regression in virus‐infected leukocyte cultures

1979 • 96 citations

The Epidemiology of Influenza

1977 • 93 citations

HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus associated with HLA A2.

1978 • 89 citations

Micromethods for induction and assay of mouse mixed lymphocyte reactions and cytotoxicity

1975 • 86 citations

Echovirus encephalitis and myositis in primary immunoglobulin deficiency.

1978 • 83 citations

Biology of the mouse histocompatibility-2 complex;: Principles of immunogenetics applied to a single system

1975 • 82 citations

Immunologic injury in measles virus infection. III. Presence and characterization of human cytotoxic lymphocytes.

1977 • 82 citations

Demonstration of HLA restricted killer cells in patients with acute measles

1979 • 82 citations

ISOLATION, STRUCTURE AND GENETICS OF HLA-A, -B, -C AND -DRw(Ia) ANTIGENS

1978 • 81 citations

Immune response in humans after vaccination with vaccinia virus: generation of a virus-specific cytotoxic activity by human peripheral lymphocytes

1977 • 79 citations

INFLUENZA AT CHRIST'S HOSPITAL: MARCH, 1974

1976 • 77 citations

Nonrandom inclusion of H-2K and H-2D antigens in Friend virus particles from mice of various strains.

1978 • 76 citations

Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses.

1977 • 75 citations

Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes.

1975 • 71 citations

HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus.

1979 • 70 citations

A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression.

1978 • 70 citations

Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells.

1976 • 69 citations

Hemagglutinin-specific cytotoxic T-cell response during influenza infection.

1977 • 66 citations

The Recovery of Mice from Influenza A Virus Infection: Adoptive Transfer of Immunity with Influenza Virus‐specific Cytotoxic T Lymphocytes Recognizing a Common Virion Antigen

1978 • 64 citations

Major histocompatibility complex-restricted antibody reactivity mainly, but not exclusively, directed against cells from male donors.

1979 • 62 citations

Virus Specificity of Human Influenza Virus-Immune Cytotoxic T Cells

1979 • 62 citations

Relationship between trinitrophenyl and H-2 antigens on trinitrophenyl-modified spleen cells. I. H-2 antigens on cells treated with trinitrobenzene sulfonic acid are derivatized.

1977 • 60 citations

THE IMPORTANCE OF H-Y INCOMPATIBILITY IN HUMAN ORGAN TRANSPLANTATION

1978 • 56 citations

Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I. T cell recognition of TNP in association with widely shared antigens.

1978 • 50 citations

EPIDEMIOLOGY OF INFLUENZA IN MAN

1979 • 49 citations

Chronic ECHO type 5 virus meningoencephalitis in X‐linked hypogammaglobulinemia

1979 • 48 citations

Human virus-infected target cells lacking HLA antigens resist specific T-lymphocyte cytolysis

1977 • 47 citations

Immunologic Injury in Measles Virus Infection

1977 • 44 citations

Selective and unidirectional membrane redistribution of an H-2 antigen with an antibody-clustered viral antigen: relationship to mechanisms of cytotoxic T-cell interactions.

1979 • 43 citations

THE MAJOR HISTOCOMPATIBILITY SYSTEM AND THE IMMUNE RESPONSE

1978 • 42 citations

Relationship between Trinitrophenyl and H-2 Antigens on Trinitrophenyl-Modified Spleen Cells

1977 • 42 citations

Monoclonal antibodies to hemagglutinin and to H‐2 inhibit the cross‐reactive cytotoxic T cell populations induced by influenza

1980 • 41 citations

Influenza virus infection of mouse lymphoblasts alters the binding affinity of anti‐H‐2 antibody: Requirement for viral neuraminidase

1979 • 39 citations

T lymphocyte response to H-2 mutants: cytotoxic effectors are Ly-1+2+.

1979 • 37 citations

Immunogenetic analysis ofH-2 mutations

1977 • 35 citations

Hypogammaglobulinaemia in the United Kingdom. VII. The role of humoral antibodies in protection against and recovery from bacterial and virus infections in hypogammaglobulinaemia.

1971 • 33 citations

Inherited disorders in the regulation of serum calcium in rats raised from parathyroidectomised mothers

1978 • 33 citations

Demonstration of T-cell and K-cell cytotoxicity against measles-infected cells in normal subjects, multiple sclerosis and subacute sclerosing panencephalitis.

1977 • 31 citations

Differences in HLA Antigen Recognition by Human Influenza Virus-Immune Cytotoxic T Cells

1979 • 31 citations

Anti-self HLA may be clonally expressed.

1979 • 31 citations

Lymohocyte-mediated cytotoxicity against influenza virus-infected cells: an in vitro method.

1975 • 30 citations

Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. II. Diversity of self determinants recognized in association with TNP.

1978 • 29 citations

Cell-mediated cytotoxicity against measles virus in SSPE. I. Enhancement by antibody.

1977 • 27 citations

Human Cytotoxic Response in Vitro to Trinitrophenyl-Modified Autologous Cells

1978 • 22 citations

Cell cytotoxicity due to specific influenza antibody production in vitro after recent influenza antigen stimulation.

1979 • 20 citations

Human Cytotoxic Response in Vitro to Trinitrophenyl-Modified Autologous Cells

1978 • 20 citations

Cell-Mediated Cytotoxicity Against Measles Virus in SSPE

1977 • 19 citations

Lymphocyte-Mediated Cytotoxicity against Influenza Virus-Infected Cells: An in Vitro Method

1975 • 18 citations

Generation on Infected Fibroblasts of Human T and Non-T Lymphocytes with Specific Cytotoxicity, Influenced by Histocompatibility, against Measles Virus-Infected Cells

1979 • 15 citations

INHIBITORS OF INFLUENZA VIRUS REPLICATION

1979 • 11 citations

The EBV-carrying, β2M/HLA deficient Burkitt lymphoma line Daudi is sensitive to EBV-specific killer T-cells of mononucleosis patients

1979 • 11 citations

Influenza: Introduction

1979 • 5 citations