Phosphorylation of the fused protein kinase in response to signaling from hedgehog.

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

Developmental Compartmentalisation of the Wing Disk of Drosophila

1973 • 770 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

Radioimmunoassay of cyclic AMP and cyclic GMP.

1979 • 553 citations

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection

1988 • 547 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1995 • 505 citations

Induction of midbrain dopaminergic neurons by Sonic hedgehog

1995 • 481 citations

Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings.

1994 • 451 citations

Role of the Drosophila patched gene in positional signalling

1991 • 414 citations

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

1992 • 400 citations

Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

1995 • 341 citations

Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs

1994 • 330 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

Drosophila hedgehog acts as a morphogen in cellular patterning

1994 • 215 citations

Requirements for hedgehog, a segmental polarity gene, in patterning larval and adult cuticle of Drosophila.

1988 • 190 citations

The role of easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo

1989 • 175 citations

Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo

1993 • 172 citations

Dual functions of wingless in the Drosophila leg imaginal disc

1995 • 167 citations

Genetic analysis of hedgehog signalling in the Drosophila embryo

1993 • 167 citations

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

1990 • 151 citations

Hedgehog and beyond

1995 • 149 citations

Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing

1995 • 145 citations

The long and short of hedgehog signaling

1995 • 134 citations

Signalling by hedgehog family proteins in Drosophila and vertebrate development

1995 • 107 citations

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

1993 • 85 citations

Secretion of the amino-terminal fragment of the Hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila

1995 • 76 citations

Pattern Formation: Hedgehog points the way

1994 • 59 citations

Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster

1993 • 38 citations