IL-3, IL-5, granulocyte-macrophage colony- stimulating factor receptor α-subunit, and common β-subunit expression by peripheral leukocytes and blood dendritic cells☆☆☆★★★

Differentiation and proliferation of hematopoietic stem cells

1993 • 1,417 citations

Cytokine receptor signalling

1995 • 1,242 citations

Recombinant human interleukin 5 is a selective activator of human eosinophil function.

1988 • 976 citations

Interleukin-5, eosinophils, and disease

1992 • 874 citations

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

1991 • 841 citations

Allergic and Nonallergic Asthmatics Have Distinct Patterns of T-Cell Activation and Cytokine Production in Peripheral Blood and Bronchoalveolar Lavage

1992 • 788 citations

Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects.

1991 • 676 citations

Cytokine Receptors and Signal Transduction

1992 • 607 citations

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3.

1988 • 490 citations

Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts.

1987 • 408 citations

Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5

1993 • 404 citations

T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma.

1991 • 395 citations

Regulatory effect of cytokines on eosinophil degranulation.

1990 • 337 citations

Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.

1996 • 332 citations

Cytokine Receptors and Signal Transduction

1997 • 259 citations

Interleukin 5 modifies histamine release and leukotriene generation by human basophils in response to diverse agonists.

1990 • 213 citations

High affinity human IgE receptor (Fc epsilon RI). Analysis of functional domains of the alpha-subunit with monoclonal antibodies

1991 • 197 citations

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

1997 • 150 citations

GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells

1992 • 142 citations

Interleukin-5, interleukin-3, and granulocyte-macrophage colony-stimulating factor cross-compete for binding to cell surface receptors on human eosinophils.

1991 • 136 citations

Human Interleukin‐3 inhibits the binding of granulocyte‐macrophage colony‐stimulating factor and interleukin‐5 to basophils and strongly enhances their functional activity

1990 • 121 citations

Residue 21 of human granulocyte-macrophage colony-stimulating factor is critical for biological activity and for high but not low affinity binding.

1992 • 112 citations

Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist

1996 • 109 citations

Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells

1993 • 107 citations

Regulation of surface expression of the granulocyte/macrophage colony-stimulating factor receptor in normal human myeloid cells.

1990 • 99 citations

Human Interleukin-3 (IL-3) Induces Disulfide-Linked IL-3 Receptor α- and β-Chain Heterodimerization, Which Is Required for Receptor Activation but Not High-Affinity Binding

1996 • 88 citations

Neutrophils activated by granulocyte-macrophage colony-stimulating factor express receptors for interleukin-3 which mediate class II expression

1995 • 83 citations

Understanding the dendritic cell lineage through a study of cytokine receptors.

1994 • 81 citations

Characterization of the human IL-5 receptors on eosinophils

1991 • 70 citations

Rapid priming of human monocytes by human hematopoietic growth factors: granulocyte-macrophage colony-stimulating factor (CSF), macrophage-CSF, and interleukin-3 selectively enhance superoxide release triggered by receptor-mediated agonists

1992 • 61 citations

Identification of Key Charged Residues of Human Interleukin-5 in Receptor Binding and Cellular Activation

1995 • 57 citations

Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively.

1995 • 50 citations

Flow cytometric analysis of cytokine receptors on human Langerhans' cells. Changes observed after short‐term culture

1996 • 47 citations

Human B cells express IL-5 receptor messenger ribonucleic acid and respond to IL-5 with enhanced IgM production after mitogenic stimulation with Moraxella catarrhalis.

1996 • 44 citations

The degradation product of the C5a anaphylatoxin C5a_desarg retains basophil‐activating properties

1994 • 35 citations

The role of alveolar macrophages and dendritic cells in allergic airway sensitization

1996 • 21 citations

Characterization of Human Leucocytes Bearing the IL-3 Receptor

1996 • 13 citations