Contribution of Sodium‐Calcium Exchange to Calcium Regulation in Cardiac Muscle^a

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

The dependence of calcium efflux from cardiac muscle on temperature and external ion composition

1968 • 1,024 citations

A model of cardiac electrical activity incorporating ionic pumps and concentration changes

1985 • 835 citations

Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum.

1986 • 710 citations

Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2

1985 • 660 citations

Identification of sodium‐calcium exchange current in single ventricular cells of guinea‐pig.

1987 • 625 citations

The Ca2+-pumping ATPase of heart sarcolemma. Characterization, calmodulin dependence, and partial purification.

1981 • 473 citations

Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 445 citations

The stoichiometry of the cardiac sodium-calcium exchange system.

1984 • 425 citations

Mechanism of release of calcium from sarcoplasmic reticulum of guinea‐pig cardiac cells.

1988 • 418 citations

Stoichiometry of sodium-calcium exchange in cardiac sarcolemmal vesicles. Coupling to the sodium pump.

1979 • 407 citations

The generation of electric currents in cardiac fibers by Na/Ca exchange

1979 • 399 citations

A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates

1985 • 398 citations

Effect of Membrane Potential Changes on the Calcium Transient in Single Rat Cardiac Muscle Cells

1987 • 353 citations

The effect of the internal sodium concentration on calcium fluxes in isolated guinea‐pig auricles

1970 • 328 citations

Regulation and deregulation of cardiac Na+–Ca2+ exchange in giant excised sarcolemmal membrane patches

1990 • 320 citations

Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude

1982 • 276 citations

Na-Ca exchange: stoichiometry and electrogenicity

1985 • 256 citations

Identification of Na-Ca exchange current in single cardiac myocytes

1986 • 220 citations

Kinetics, stoichiometry and role of the Na–Ca exchange mechanism in isolated cardiac myocytes

1990 • 192 citations

Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum calcium pump. Ryanodine and voltage sensitivity.

1989 • 179 citations

Sodium-Calcium Exchange in Heart: Membrane Currents and Changes in [Ca ²⁺ ] _i

1987 • 175 citations

A mechanism for Na/Ca transport.

1977 • 174 citations

Molecular operations of the sodium–calcium exchanger revealed by conformation currents

1991 • 161 citations

Equilibrium calcium-calcium exchange in cardiac sarcolemmal vesicles.

1983 • 158 citations

A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers

1987 • 144 citations

Contraction in voltage-clamped, internally perfused single heart cells.

1986 • 136 citations

Measurement of reversal potential of Na+‐Ca2+ exchange current in single guinea‐pig ventricular cells.

1989 • 136 citations

Epinephrine enhances Ca2+ current-regulated Ca2+ release and Ca2+ reuptake in rat ventricular myocytes.

1988 • 132 citations

Ryanodine as a tool to determine the contributions of calcium entry and calcium release to the calcium transient and contraction of cardiac Purkinje fibers.

1985 • 126 citations

Limitations of the whole cell patch clamp technique in the control of intracellular concentrations

1990 • 119 citations

Relaxation of Isolated Ventricular Cardiomyocytes by a Voltage-Dependent Process

1988 • 108 citations

Sodium-Calcium Exchange

1990 • 104 citations

"Creep currents" in single frog atrial cells may be generated by electrogenic Na/Ca exchange.

1986 • 86 citations

A novel experimental chamber for single-cell voltage-clamp and patch-clamp applications with low electrical noise and excellent temperature and flow control

1986 • 69 citations

Sodium–Calcium Exchange and Its Role in Generating Electric Current

1986 • 43 citations

Effects of membrane potential on intracellular calcium concentration in sheep Purkinje fibres in sodium‐free solutions.

1986 • 16 citations