Effect of Membrane Potential Changes on the Calcium Transient in Single Rat Cardiac Muscle Cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 904 citations

A novel type of cardiac calcium channel in ventricular cells

1985 • 745 citations

Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.

1985 • 715 citations

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

1975 • 684 citations

Measurement of Ca2+ concentrations in living cells

1982 • 664 citations

Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2

1985 • 660 citations

The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle.

1982 • 560 citations

Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 445 citations

Electrical properties of individual cells isolated from adult rat ventricular myocardium.

1980 • 394 citations

Cellular and Subcellular Heterogeneity of [Ca ²⁺ ] _i in Single Heart Cells Revealed by Fura-2

1987 • 345 citations

Excitation-contraction coupling in heart muscle: Membrane control of development of tension

1973 • 304 citations

The relation between membrane potential, membrane currents and activation of contraction in ventricular myocardial fibres

1970 • 302 citations

Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude

1982 • 276 citations

Inactivation of calcium channel current in the calf cardiac Purkinje fiber. Evidence for voltage- and calcium-mediated mechanisms.

1984 • 272 citations

Oscillations of intracellular Ca2+ in mammalian cardiac muscle

1983 • 266 citations

Reversal of current through calcium channels in dialysed single heart cells

1982 • 241 citations

Relationship between force and intracellular [Ca2+] in tetanized mammalian heart muscle.

1986 • 198 citations

The ionic nature of slow inward current and its relation to contraction

1972 • 191 citations

Cellular calcium fluctuations in mammalian heart: direct evidence from noise analysis of aequorin signals in Purkinje fibers.

1983 • 181 citations

A comparison of calcium currents in rat and guinea pig single ventricular cells.

1984 • 167 citations

Voltage dependence of intracellular [Ca2+]i transients in guinea pig ventricular myocytes.

1987 • 164 citations

Calcium conductance and tension in mammalian ventricular muscle

1975 • 164 citations

Contraction in voltage-clamped, internally perfused single heart cells.

1986 • 136 citations

Isolation of calcium current and its sensitivity to monovalent cations in dialysed ventricular cells of guinea‐pig.

1984 • 132 citations

The control of tonic tension by membrane potential and intracellular sodium activity in the sheep cardiac Purkinje fibre.

1983 • 130 citations

The kinetics of calcium binding to fura‐2 and indo‐1

1987 • 130 citations

Slow inward current and contraction of sheep cardiac Purkinje fibers.

1975 • 101 citations

Active and passive electrical properties of single bullfrog atrial cells.

1981 • 96 citations

Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock.

1984 • 95 citations

The dependence of cardiac contraction on depolarization and slow inward current

1971 • 92 citations

Fura‐2 diffusion and its use as an indicator of transient free calcium changes in single striated muscle cells

1986 • 74 citations

A novel experimental chamber for single-cell voltage-clamp and patch-clamp applications with low electrical noise and excellent temperature and flow control

1986 • 69 citations

Intracellular [Ca2+] transients in voltage clamped cardiac Purkinje fibers

1982 • 61 citations

Birth and growth of the European Society of Cardiology

1980 • 18 citations

Effects of membrane potential on intracellular calcium concentration in sheep Purkinje fibres in sodium‐free solutions.

1986 • 16 citations

Measurement of intracellular calcium during the development and relaxation of tonic tension in sheep Purkinje fibres.

1986 • 9 citations