Ryanodine as a tool to determine the contributions of calcium entry and calcium release to the calcium transient and contraction of cardiac Purkinje fibers.

Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum

1983 • 1,884 citations

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

1983 • 1,010 citations

Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

1983 • 869 citations

Contractions induced by a calcium‐triggered release of calcium from the sarcoplasmic reticulum of single skinned cardiac cells.

1975 • 684 citations

Measurement of Ca2+ concentrations in living cells

1982 • 664 citations

Calcium transients in aequorin-injected frog cardiac muscle

1978 • 441 citations

Excitation-Contraction Coupling

1976 • 355 citations

Excitation-contraction coupling in heart muscle: Membrane control of development of tension

1973 • 304 citations

Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude

1982 • 276 citations

The pharmacology of ryanodine.

1969 • 240 citations

Calcium‐activated transient outward current in calf cardiac Purkinje fibres.

1980 • 237 citations

Excitation-contraction coupling in cardiac muscle

1980 • 227 citations

Inward membrane currents in mammalian myocardium

1972 • 223 citations

Effects of caffeine on Ca-activated force production in skinned cardiac and skeletal muscle fibres of the rat

1983 • 221 citations

Ryanodine modification of cardiac muscle responses to potassium-free solutions. Evidence for inhibition of sarcoplasmic reticulum calcium release.

1983 • 191 citations

Calcium release in skinned cardiac cells: variations with species, tissues, and development.

1982 • 186 citations

Cellular calcium fluctuations in mammalian heart: direct evidence from noise analysis of aequorin signals in Purkinje fibers.

1983 • 181 citations

Department of Physiology

1969 • 163 citations

Excitation-contraction coupling in cardiac Purkinje fibers. Effects of cardiotonic steroids on the intracellular [Ca2+] transient, membrane potential, and contraction.

1984 • 154 citations

Influence of chloride, potassium, and tetraethylammonium on the early outward current of sheep cardiac Purkinje fibers.

1979 • 145 citations

Rapid photochemical inactivation of Ca2+-antagonists shows that Ca2+ entry directly activates contraction in frog heart

1983 • 143 citations

Ryanodine: its alterations of cat papillary muscle contractile state and responsiveness to inotropic interventions and a suggested mechanism of action.

1979 • 112 citations

Calcium Transients During Excitation-Contraction Coupling in Mammalian Heart: Aequorin Signals of Canine Purkinje Fibers

1980 • 106 citations

Ryanodine-induced stimulation of net Ca++ uptake by cardiac sarcoplasmic reticulum vesicles.

1979 • 104 citations

Ryanodine prolongs Ca‐currents while suppressing contraction in rat ventricular muscle cells

1984 • 99 citations

Excitation-contraction coupling in cardiac Purkinje fibers. Effects of caffeine on the intracellular [Ca2+] transient, membrane currents, and contraction.

1984 • 93 citations

Ca Entry and Contraction as Studied in Isolated Bovine Ventricular Myocytes

1982 • 78 citations

Activation-dependent cumulative depletions of extracellular free calcium in guinea pig atrium measured with antipyrylazo III and tetramethylmurexide.

1983 • 69 citations

Potential and tension changes induced by sodium removal in dog Purkinje fibres: role of an electrogenic sodium-calcium exchange.

1981 • 69 citations

Relationships between voltage and tension in sheep cardiac Purkinje fibers.

1975 • 65 citations

Effects of nystatin‐mediated intracellular ion substitution on membrane currents in calf Purkinje fibres

1982 • 61 citations

Intracellular [Ca2+] transients in voltage clamped cardiac Purkinje fibers

1982 • 61 citations

Inhibition of transient outward current by intracellular ion substitution unmasks slow inward calcium current in cardiac Purkinje fibers

1981 • 20 citations