Drosophila melanogaster P Transposable Elements: Mechanisms of Transposition and Regulation

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

Structures of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome

1983 • 794 citations

HYBRID DYSGENESIS IN DROSOPHILA MELANOGASTER: A SYNDROME OF ABERRANT TRAITS INCLUDING MUTATION, STERILITY AND MALE RECOMBINATION

1977 • 784 citations

Analysis of P transposable element functions in drosophila

1984 • 733 citations

DNA end-joining: from yeast to man

1998 • 586 citations

The molecular basis of P-M hybrid dysgenesis: The role of the P element, a P-strain-specific transposon family

1982 • 569 citations

Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing

1986 • 568 citations

The molecular basis of P-M hybrid dysgenesis: The nature of induced mutations

1982 • 484 citations

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project.

1995 • 472 citations

Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method

1981 • 446 citations

Type I repressors of P element mobility.

1993 • 421 citations

Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis.

1992 • 403 citations

Targeted Gene Replacement in Drosophila Via P Element-Induced Gap Repair

1991 • 352 citations

Identification and immunochemical analysis of biologically active Drosophila P element transposase

1986 • 318 citations

THE P FAMILY OF TRANSPOSABLE ELEMENTS IN DROSOPHILA

1983 • 310 citations

It takes two transposons to tango:transposable-element-mediated chromosomal rearrangements

2000 • 287 citations

Taming of transposable elements by homology-dependent gene silencing

1999 • 221 citations

Insertion site preferences of the P transposable element in Drosophila melanogaster

2000 • 205 citations

Cytotype control of Drosophila P element transposition: The 66 kd protein is a repressor of transposase activity

1990 • 188 citations

Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA

1991 • 159 citations

The mechanism of somatic inhibition of Drosophila P-element pre-mRNA splicing: multiprotein complexes at an exon pseudo-5' splice site control U1 snRNP binding.

1992 • 154 citations

Regulated Splicing of the Drosophila P Transposable Element Third Intron in Vitro: Somatic Repression

1990 • 149 citations

MOLECULAR MECHANISMS REGULATING DROSOPHILA P ELEMENT TRANSPOSITION

1990 • 148 citations

Flanking Duplications and Deletions Associated With P-Induced Male Recombination in Drosophila

1996 • 147 citations

P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor

1992 • 142 citations

Modified P elements that mimic the P cytotype in Drosophila melanogaster.

1989 • 138 citations

Drosophila P element transposase recognizes internal P element DNA sequences

1989 • 136 citations

cis-acting DNA sequence requirements for P-element transposition.

1989 • 132 citations

The maternally inherited regulation of P elements in Drosophila melanogaster can be elicited by two P copies at cytological site 1A on the X chromosome.

1991 • 126 citations

Regulation of tissue-specific P-element pre-mRNA splicing requires the RNA-binding protein PSI.

1994 • 124 citations

Drosophila P-element transposase is a novel site-specific endonuclease

1997 • 122 citations

Soma-specific expression and cloning of PSI, a negative regulator of P element pre-mRNA splicing.

1995 • 118 citations

Identification and purification of a Drosophila protein that binds to the terminal 31-base-pair inverted repeats of the P transposable element.

1988 • 109 citations

HETEROZYGOUS EFFECTS ON VIABILITY, FERTILITY, RATE OF DEVELOPMENT, AND LONGEVITY OF DROSOPHILA CHROMOSOMES THAT ARE LETHAL WHEN HOMOZYGOUS

1960 • 100 citations

HYBRID DYSGENESIS IN DROSOPHILA MELANOGASTER: NATURE AND INHERITANCE OF P ELEMENT REGULATION

1985 • 98 citations

Studies on the rate and site-specificity of P element transposition.

1991 • 96 citations

Transposase titration in Drosophila melanogaster: a model of cytotype in the P-M system of hybrid dysgenesis.

1985 • 90 citations

Maternal repression of the P element promoter in the germline of Drosophila melanogaster: a model for the P cytotype.

1993 • 79 citations

A Drosophila protein homologous to the human p70 Ku autoimmune antigen interacts with the P transposable element inverted repeats.

1994 • 79 citations

COMPONENTS OF HYBRID DYSGENESIS IN A WILD POPULATION OF DROSOPHILA MELANOGASTER

1980 • 79 citations

The Drosophila micropia retrotransposon encodes a testis-specific antisense RNA complementary to reverse transcriptase.

1994 • 78 citations

Modulation of P-Element Pre-mRNA Splicing by a Direct Interaction between PSI and U1 snRNP 70K Protein

2001 • 75 citations

Repression of hybrid dysgenesis in Drosophila melanogaster by individual naturally occurring P elements.

1993 • 74 citations

A role for the KP leucine zipper in regulating P element transposition in Drosophila melanogaster.

1995 • 73 citations

P-element-induced interallelic gene conversion of insertions and deletions in Drosophila melanogaster.

1993 • 71 citations

Distribution and structure of cloned P elements from theDrosophila melanogasterP strain π₂

1992 • 69 citations

P-Element-Induced Recombination in Drosophila melanogaster: Hybrid Element Insertion

1996 • 68 citations

The Drosophila P-Element KP Repressor Protein Dimerizes and Interacts with Multiple Sites on P-Element DNA

1996 • 67 citations

DNA binding by the KP repressor protein inhibits P-element transposase activity in vitro

1998 • 65 citations

Analysis of the cis-acting requirements for germ-line-specific splicing of the P-element ORF2-ORF3 intron.

1989 • 64 citations

HYBRID DYSGENESIS IN DROSOPHILA MELANOGASTER: THE GENETICS OF CYTOTYPE DETERMINATION IN A NEUTRAL STRAIN

1981 • 64 citations

Cosuppression of I Transposon Activity in Drosophila by I-Containing Sense and Antisense Transgenes

1999 • 62 citations

Protected P-element termini suggest a role for inverted-repeat-binding protein in transposase-induced gap repair in Drosophila melanogaster.

1995 • 61 citations

P-element repressor autoregulation involves germ-line transcriptional repression and reduction of third intron splicing.

1995 • 59 citations

Trans-Silencing by P Elements Inserted in Subtelomeric Heterochromatin Involves the Drosophila Polycomb Group Gene, Enhancer of zeste

1998 • 56 citations

Drosophila P-element transposase is a transcriptional repressor in vitro.

1991 • 55 citations

Maternal inheritance of P cytotype in Drosophila melanogaster: a “pre-P cytotype” is strictly extra-chromosomally transmitted

1993 • 52 citations

Telomeric P elements Associated With Cytotype Regulation of the P Transposon Family in Drosophila melanogaster

2002 • 52 citations

P regulatory products repress in vivo the P promoter activity in P-lacZ fusion genes.

1991 • 51 citations

Electron microscopical analysis of Drosophila polytene chromosomes

1985 • 51 citations

Localization of P elements, copy number regulation, and cytotype determination inDrosophila melanogaster

1990 • 48 citations

The accumulation of P-elements on the tip of theXchromosome in populations ofDrosophila melanogaster

1989 • 48 citations

Identification of a cis-acting sequence required for germ line-specific splicing of the P element ORF2-ORF3 intron.

1991 • 47 citations

The geographical distribution of P-M hybrid dysgenesis in Drosophila melanogaster

1984 • 46 citations

Differences inPelement population dynamics between the sibling speciesDrosophila melanogasterandDrosophila simulans

1994 • 45 citations

Cytotype control of Drosophila melanogaster P element transposition: genomic position determines maternal repression.

1993 • 44 citations

Distinct P-Element Excision Products in Somatic and Germline Cells of Drosophila melanogaster

2000 • 44 citations

P-Element Repression in Drosophila melanogaster by Variegating Clusters of P-lacZ-white Transgenes

2001 • 39 citations

The P-M Hybrid Dysgenesis Cline in Eastern Australian Drosophila melanogaster: Discrete P, Q and M Regions Are Nearly Contiguous

1987 • 39 citations

The KH-type RNA-binding protein PSI is required for Drosophila viability, male fertility, and cellular mRNA processing

2002 • 37 citations

Electron microscopical analysis of Drosophila polytene chromosomes

1986 • 35 citations

Hybrid Dysgenesis in Drosophila melanogaster: Evidence from Sterility and Southern Hybridization Tests that P Cytotype Is Not Maintained in the Absence of Chromosomal P Factors

1987 • 34 citations

Repression of Hybrid Dysgenesis in Drosophila melanogaster by Heat-Shock-Inducible Sense and Antisense P-Element Constructs

1996 • 30 citations

Stability of European natural populations of Drosophila melanogaster with regard to the P–M system: a buffer zone made up of Q populations

1999 • 30 citations

In vivo gap repair in Drosophila: a one-way street with many destinations

1998 • 30 citations

Origin and decay of the P element-associated latitudinal cline in Australian Drosophila melanogaster.

1998 • 29 citations

P-element-induced male recombination can be produced in Drosophila melanogaster by combining end-deficient elements in trans.

1995 • 29 citations

A hobo Transgene That Encodes the P-Element Transposase in Drosophila melanogaster: Autoregulation and Cytotype Control of Transposase Activity

2002 • 29 citations

Gene conversion in mitotically dividing cells: a view from Drosophila

1998 • 26 citations

Regulation of P-Element Transposase Activity in Drosophila melanogaster by hobo Transgenes That Contain KP Elements

2002 • 25 citations

A latitudinal cline inP–Mgonadal dysgenesis potential in AustralianDrosophila melanogasterpopulations

1987 • 25 citations

The DNA-dependent protein kinase: a matter of life and (cell) death

1996 • 24 citations

Genomic P elements and P-M characteristics of eastern Australian populations of Drosophila melanogaster.

1999 • 22 citations

The Role of Host Factors in the Population Dynamics of Selfish Transposable Elements

1997 • 20 citations

Maternal transmission of P element transposase activity in Drosophila melanogaster depends on the last P intron

2002 • 19 citations

Natural Repressors of P-induced hybrid dysgenesis inDrosophila melanogaster: a model for repressor evolution

1996 • 16 citations

Negative regulation of P element excision by the somatic product and terminal sequences of P in Drosophila melanogaster

1993 • 13 citations

Evolutionary flux of P element regulation in a Drosophila melanogaster hybrid dysgenesis cline

1999 • 10 citations