Genome-scale analyses of health-promoting bacteria: probiogenomics

An obesity-associated gut microbiome with increased capacity for energy harvest

2006 • 11,120 citations

Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics

1995 • 7,436 citations

Diversity of the Human Intestinal Microbial Flora

2005 • 7,395 citations

The gut microbiota as an environmental factor that regulates fat storage

2004 • 5,730 citations

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

2007 • 5,623 citations

The Human Microbiome Project

2007 • 5,410 citations

Host-Bacterial Mutualism in the Human Intestine

2005 • 4,852 citations

Prokaryotes: The unseen majority

1998 • 4,659 citations

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

2007 • 4,230 citations

Evolution of Mammals and Their Gut Microbes

2008 • 3,434 citations

Gut flora in health and disease

2003 • 3,233 citations

Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine

2006 • 3,102 citations

Commensal Host-Bacterial Relationships in the Gut

2001 • 2,278 citations

Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

2005 • 2,123 citations

H<scp>OW</scp>H<scp>OST</scp>-M<scp>ICROBIAL</scp>I<scp>NTERACTIONS</scp>S<scp>HAPE THE</scp>N<scp>UTRIENT</scp>E<scp>NVIRONMENT OF THE</scp>M<scp>AMMALIAN</scp>I<scp>NTESTINE</scp>

2002 • 1,558 citations

Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis

2008 • 1,539 citations

Complete genome sequence of Lactobacillus plantarum WCFS1

2003 • 1,399 citations

Comparative genomics of the lactic acid bacteria

2006 • 1,332 citations

Glycan Foraging in Vivo by an Intestine-Adapted Bacterial Symbiont

2005 • 1,117 citations

Horizontal Gene Transfer in Prokaryotes: Quantification and Classification

2001 • 1,113 citations

List of Bacterial Names with Standing in Nomenclature: a Folder Available on the Internet

1997 • 1,091 citations

Genomics ofActinobacteria: Tracing the Evolutionary History of an Ancient Phylum

2007 • 995 citations

The Fecal Microbiota of Irritable Bowel Syndrome Patients Differs Significantly From That of Healthy Subjects

2007 • 976 citations

The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract

2002 • 929 citations

Bacteria of Dental Caries in Primary and Permanent Teeth in Children and Young Adults

2008 • 893 citations

The serpin superfamily of proteinase inhibitors: structure, function, and regulation.

1994 • 879 citations

Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118

2007 • 787 citations

The model organism as a system: integrating 'omics' data sets

2006 • 776 citations

Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon

2003 • 733 citations

Analysis of the Fecal Microflora of Human Subjects Consuming a Probiotic Product Containing Lactobacillus rhamnosus DR20

2000 • 668 citations

A humanized gnotobiotic mouse model of host–archaeal–bacterial mutualism

2006 • 624 citations

Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial

2007 • 586 citations

Complete genome sequence of the probiotic lactic acid bacteriumLactobacillus acidophilusNCFM

2005 • 579 citations

Diversity of the human gastrointestinal tract microbiota revisited

2007 • 533 citations

A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem

1999 • 493 citations

The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533

2004 • 471 citations

Probiotic and other functional microbes: from markets to mechanisms

2005 • 451 citations

Production and isolation of reuterin, a growth inhibitor produced by Lactobacillus reuteri

1988 • 433 citations

Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids

2005 • 422 citations

Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model

2008 • 413 citations

Genomic and Metabolic Studies of the Impact of Probiotics on a Model Gut Symbiont and Host

2006 • 410 citations

The complete genome sequence ofLactobacillus bulgaricusreveals extensive and ongoing reductive evolution

2006 • 396 citations

Acquired antibiotic resistance in lactic acid bacteria from food.

1999 • 374 citations

Towards understanding molecular modes of probiotic action

2006 • 335 citations

Getting better with bifidobacteria

2005 • 332 citations

Mucin degradation in human colon ecosystems. Isolation and properties of fecal strains that degrade ABH blood group antigens and oligosaccharides from mucin glycoproteins.

1985 • 314 citations

Biodiversity-Based Identification and Functional Characterization of the Mannose-Specific Adhesin ofLactobacillus plantarum

2005 • 299 citations

Comparative Genome Analysis of Lactobacillus reuteri and Lactobacillus fermentum Reveal a Genomic Island for Reuterin and Cobalamin Production

2008 • 285 citations

Mucin Degradation in Human Colon Ecosystems

1981 • 274 citations

Evolutionary Genomics of Lactic Acid Bacteria

2007 • 262 citations

Stable Coexistence of Five Bacterial Strains as a Cellulose-Degrading Community

2005 • 255 citations

Defining Genomic Islands and Uropathogen-Specific Genes in Uropathogenic Escherichia coli

2007 • 246 citations

Molecular Cloning and Characterization of Bifidobacterium bifidum 1,2-α- <scp>l</scp> -Fucosidase (AfcA), a Novel Inverting Glycosidase (Glycoside Hydrolase Family 95)

2004 • 237 citations

Identification ofLactobacillus plantarumGenes That Are Induced in the Gastrointestinal Tract of Mice

2004 • 234 citations

Human gut microbiota and bifidobacteria: from composition to functionality

2008 • 232 citations

Genomic features of lactic acid bacteria effecting bioprocessing and health

2005 • 224 citations

Multireplicon genome architecture of Lactobacillus salivarius

2006 • 216 citations

Human milk provides peptides highly stimulating the growth of bifidobacteria

2002 • 216 citations

A Five-Strain Probiotic Combination Reduces Pathogen Shedding and Alleviates Disease Signs in Pigs Challenged with Salmonella enterica Serovar Typhimurium

2007 • 215 citations

Probiotics and gastrointestinal diseases

2004 • 196 citations

Mucin Degradation by Bifidobacterium Strains Isolated from the Human Intestinal Microbiota

2008 • 196 citations

Genome Sequence of Lactobacillus helveticus , an Organism Distinguished by Selective Gene Loss and Insertion Sequence Element Expansion

2007 • 196 citations

Genomic features of lactic acid bacteria effecting bioprocessing and health

2005 • 195 citations

Insights into the taxonomy, genetics and physiology of bifidobacteria

2004 • 194 citations

Screening for and Identification of Starch-, Amylopectin-, and Pullulan-Degrading Activities in Bifidobacterial Strains

2006 • 185 citations

Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth

2008 • 180 citations

The genomics of lactic acid bacteria

2007 • 175 citations

Identification of Genes Associated with the Long-Gut-Persistence Phenotype of the Probiotic Lactobacillus johnsonii Strain NCC533 Using a Combination of Genomics and Transcriptome Analysis

2008 • 167 citations

A Serpin from the Gut Bacterium Bifidobacterium longum Inhibits Eukaryotic Elastase-like Serine Proteases

2006 • 161 citations

Bifidobacterium carbohydrases‐their role in breakdown and synthesis of (potential) prebiotics

2007 • 157 citations

Analysis of bifidobacterial evolution using a multilocus approach

2006 • 157 citations

Lactobacillus reuteri DSM 20016 Produces Cobalamin-Dependent Diol Dehydratase in Metabolosomes and Metabolizes 1,2-Propanediol by Disproportionation

2008 • 140 citations

Lessons from the genomes of bifidobacteria

2005 • 138 citations

Diversity of the genus Lactobacillus revealed by comparative genomics of five species

2006 • 127 citations

Identification of Lactobacillus reuteri Genes Specifically Induced in the Mouse Gastrointestinal Tract

2003 • 126 citations

Lessons from the genomes of bifidobacteria

2005 • 124 citations

Mechanisms of Action of Probiotics in Intestinal Diseases

2007 • 123 citations

Lactobacillus phylogenomics - towards a reclassification of the genus

2008 • 115 citations

The complete coenzyme B12 biosynthesis gene cluster of Lactobacillus reuteri CRL1098

2008 • 110 citations

Lactobacillus plantarum gene clusters encoding putative cell-surface protein complexes for carbohydrate utilization are conserved in specific gram-positive bacteria

2006 • 108 citations

The complete genomes of Lactobacillus plantarum and Lactobacillus johnsonii reveal extensive differences in chromosome organization and gene content

2004 • 106 citations

Similarity and Differences in the Lactobacillus acidophilus Group Identified by Polyphasic Analysis and Comparative Genomics

2006 • 106 citations

Genomics as a means to understand bacterial phylogeny and ecological adaptation: the case of bifidobacteria

2006 • 105 citations

Transcriptional Regulation and Characterization of a Novel β-Fructofuranosidase-Encoding Gene from Bifidobacterium breve UCC2003

2005 • 105 citations

Differential Transcriptional Response of Bifidobacterium longum to Human Milk, Formula Milk, and Galactooligosaccharide

2008 • 92 citations

Identification and Characterization of a Fructose Phosphotransferase System in Bifidobacterium breve UCC2003

2006 • 84 citations

Type I arabinogalactan contains β-d-Galp-(1→3)-β-d-Galp structural elements

2005 • 67 citations

Identification of the Gene for ?-Fructofuranosidase of Bifidobacterium lactis DSM10140 T and Characterization of the Enzyme Expressed in Escherichia coli

2003 • 66 citations

Gene Expression of Commensal Lactobacillus johnsonii Strain NCC533 during In Vitro Growth and in the Murine Gut

2007 • 62 citations

Differential Activities of FourLactobacillus caseiPromoters during Bacterial Transit through the Gastrointestinal Tracts of Human-Microbiota-Associated Mice

2005 • 43 citations

Extensive horizontal transfer of core genome genes between two Lactobacillus species found in the gastrointestinal tract

2007 • 39 citations

Inhibition of Vaginal Lactobacilli by a Bacteriocin-Like Inhibitor Produced by Enterococcus faecium 62-6: Potential Significance for Bacterial Vaginosis

2003 • 23 citations