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2014 • 2,466 citations

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1984 • 672 citations

Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

1988 • 539 citations

Protein Binding of Diphenylhydantoin and Desmethylimipramine in Plasma from Patients with Poor Renal Function

1971 • 296 citations

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA

1990 • 143 citations

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1974 • 124 citations

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1949 • 121 citations

The Alteration of Plasma Proteins in Uremia as Reflected in their Ability to Bind Digitoxin and Diphenylhydantoin

1972 • 118 citations

Evaluation of cyclosporin‐phenytoin interaction with observations on cyclosporin metabolites.

1984 • 112 citations

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1990 • 101 citations

Diphenylhydantoin elimination kinetics in overdosed children

1975 • 68 citations

Interaction between phenytoin and cyclosporine following organ transplantation.

1984 • 65 citations

Pharmacokinetic study of a patient with diphenylhydantoin toxicity

1973 • 57 citations

Interindividual Differences in the Protein Binding of Sulfonamides: The Effect of Disease and Drugs ¹,²

1971 • 57 citations

Acta Pharmacologica et Toxicologica

1946 • 51 citations

Cyclosporin‐phenytoin interaction: re‐evaluation using metabolite data.

1987 • 48 citations

The effects of cyclosporin A (CsA) on hepatic microsomal drug metabolism in the rat.

1986 • 36 citations

Diabetogenic effect of cyclosporin.

1987 • 31 citations

Kinetic analysis of phenytoin disposition in rats with experimental renal and hepatic diseases.

1988 • 21 citations

Cyclosporine-phenytoin interaction.

1988 • 21 citations

Is cyclosporin A an inhibitor of drug metabolism?

1990 • 21 citations

Inhibition and induction of drug biotransformation in vivo by 8-methoxypsoralen: studies of caffeine, phenytoin and hexobarbital metabolism in the rat.

1987 • 18 citations

Landmark perspective: Introduction of sodium diphenyl hydantoinate

1984 • 1 citations