irreversible selective blockade of κ-opioid receptors in the guinea-pig ileum

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

CHARACTERIZATION OF THE k‐SUBTYPE OF THE OPIATE RECEPTOR IN THE GUINEA‐PIG BRAIN

1981 • 423 citations

A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities

1980 • 287 citations

A kappa opioid effect: increased urination in the rat.

1983 • 224 citations

Selectivities of opioid peptide analogues as agonists and antagonists at the δ‐receptor

1984 • 171 citations

Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors.

1980 • 129 citations

Specific protection of the binding sites of D-Ala ² -D-Leu ⁵ - enkephalin (δ-receptors) and dihydromorphine (μ-receptors)

1979 • 121 citations

Improved assays for the assessment of ϰ- and δ-properties of opioid ligands

1982 • 69 citations

6.beta.-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5.alpha.-epoxy-3,14-dihydroxymorphinan (chloranaltrexamine), a potent opioid receptor alkylating agent with ultralong narcotic antagonist activity

1978 • 60 citations

Site-directed alkylation of multiple opioid receptors. II. Pharmacological selectivity.

1984 • 59 citations

Determination of the receptor selectivity of opioid agonists in the guinea‐pig ileum and mouse vas deferens by use of β‐funaltrexamine

1985 • 48 citations

TENA, a selective kappa opioid receptor antagonist

1985 • 47 citations

Mu-receptor binding in physiological media: Comparison with isolated tissue data

1984 • 12 citations

Effects of opiates on urine output in the water-loaded rat and reversal by β-funaltrexamine

1985 • 9 citations