Differential effect of cytokines on the phenobarbital or 3-methylcholanthrene induction of P450 mediated monooxygenase activity in cultured rat hepatocytes

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Interleukin-6 and the acute phase response

1990 • 2,740 citations

The Reticuloendothelial System

1985 • 316 citations

ALTERED THEOPHYLLINE PHARMACOKINETICS DURING ACUTE RESPIRATORY VIRAL ILLNESS

1978 • 283 citations

The reticuloendothelial system: A comprehensive treatise

1984 • 224 citations

INTERLEUKIN-1BETAINCREASES PROSTAGLANDIN E₂IN RAT ASTROCYTE CULTURES: MODULATORY EFFECT OF NEUROPEPTIDES

1989 • 173 citations

Suppression of constitutive cytochrome P-450 gene expression in livers of rats undergoing an acute phase response to endotoxin.

1989 • 164 citations

Role of interleukin-1 in the depression of liver drug metabolism by endotoxin

1986 • 142 citations

Interleukin-1 beta suppresses the induction of P4501A1 and P4501A2 mRNAs in isolated hepatocytes.

1992 • 139 citations

Biological Basis of Detoxication

1983 • 130 citations

Effects of interleukin-6 on cytochrome P450-dependent mixed-function oxidases in the rat

1992 • 110 citations

Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells

1992 • 96 citations

Advances in Immunopharmacology

1989 • 89 citations

Interleukin-1 (IL-1) depresses cytochrome P450 levels and activities in mice

1987 • 89 citations

Regulation of cytochrome P450IIC12 expression by interleukin-1 alpha, interleukin-6, and dexamethasone.

1991 • 86 citations

Homogeneous interferon from E. coli depresses hepatic cytochrome P-450 and drug biotransformation

1982 • 84 citations

Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

1988 • 74 citations

Dexamethasone Modulation of In Vivo Effects of Endotoxin, Tumor Necrosis Factor, and Interleukin-1 on Liver Cytochrome P-450, Plasma Fibrinogen, and Serum Iron

1989 • 72 citations

Depression of Drug-metabolizing Activity in the Human Liver by Interferon-β

1993 • 65 citations

Human recombinant IL-1 alters glucocorticoid receptor function in Reuber hepatoma cells.

1988 • 58 citations

Ethanol-mediated increase in cytochrome p-450 in cultured hepatocytes

1981 • 57 citations

Effect of interleukin 6 on phenobarbital induction of cytochrome P-450IIB in cultured rat hepatocytes

1991 • 53 citations

Induction of cytochrome P-450 and 5-aminolevulinate synthase activities in cultured rat hepatocytes.

1990 • 52 citations

Depression of drug metabolizing activity in the human liver by interferon-?

1990 • 51 citations

Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

1991 • 46 citations

Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes

1986 • 45 citations

Interleukin-1 beta is more potent than interleukin-1 alpha in supressing follicle-stimulating hormone-induced differentiation of ovarian granulosa cells

1989 • 42 citations

Rat but not human interferons suppress hepatic oxidative drug metabolism in rats

1989 • 36 citations

Relationships between the Enzymes of Detoxication and Host Defense Mechanisms

1983 • 36 citations

Induction and depression of cytochrome P-450-dependent mixed-function oxidase by a cloned consensus α-interferon (IFN-αCON1) in the hamster

1989 • 34 citations

Advances in Immunopharmacology

1981 • 33 citations

The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid- poly cytidylic acid

1992 • 26 citations

Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats.

1993 • 22 citations

The influence of recombinant DNA-derived human and murine gamma interferons on mouse hepatic drug metabolism

1986 • 19 citations

Mouse interferon gamma pretreated hepatocytes conditioned media suppress cytochrome P-450 induction by TCDD in mouse hepatoma cells.

1993 • 8 citations

Effect of endotoxin to differentially affect cytochrome P-450 monooxygenase activities of untreated rats and animals induced with phenobarbital or 3-methylcholanthrene

1989 • 7 citations

Pharmacokinetic and Pharmacodynamic Parameters Affected by RE Cell Activators

1985 • 7 citations

Pharmacokinetics of Immunomodulators

1990 • 2 citations