Homogeneous interferon from E. coli depresses hepatic cytochrome P-450 and drug biotransformation

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Interferon-induced enzymatic activities and their role in the antiviral state

1979 • 392 citations

ALTERED THEOPHYLLINE PHARMACOKINETICS DURING ACUTE RESPIRATORY VIRAL ILLNESS

1978 • 283 citations

Induction of drug metabolism. I. Differences in the mechanisms by which polycyclic hydrocarbons and phenobarbital produce their inductive effects on microsomal N-demethylating systems.

1969 • 218 citations

Depression of hepatic cytochrome P-450-dependent monooxygenase systems with administered interferon inducing agents

1976 • 194 citations

Comparison of the Antiviral Activities of Various Cloned Human Interferon- Subtypes in Mammalian Cell Cultures

1981 • 164 citations

Antiviral activities of hybrids of two major human leukocyte interferons

1981 • 148 citations

EFFECTS OF INTERFERON‐INDUCING AGENTS ON HEPATIC CYTOCHROME P‐450 DRUG METABOLIZING SYSTEMS*

1980 • 104 citations

Inhibition of drug-metabolizing enzymes in the rat after bacillus calmette-guérin treatment

1976 • 91 citations

Depression of the hepatic cytochrome P-450 mono-oxygenase system by administered tilorone (2,7-bis(2-(diethylamino)ethoxy)fluoren-9-one dihydrochloride).

1976 • 66 citations

Properties of a Human Alpha-Interferon Purified fromE. ColiExtracts

1981 • 61 citations

Type II interferon induction and passive transfer depress the murine cytochrome P-450 drug metabolism system

1980 • 44 citations

Depression of hepatic cytochrome P-450-dependent mixed function oxidases durino infection with encephalomyocarditis virus

1981 • 43 citations

Role of mononuclear phagocytes in decreased hepatic drug metabolism following administration of Corynebacterium parvum

1979 • 32 citations

CANCER IMMUNOTHERAPY AND DRUG DISPOSITION

1977 • 19 citations