Mechanism of age related macular degeneration

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration

2000 • 1,987 citations

Prevalence of Age-related Maculopathy

1992 • 1,864 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

1995 • 1,280 citations

The Five-year Incidence and Progression of Age-related Maculopathy

1997 • 1,144 citations

Prevalence of Age-related Maculopathy in Australia

1995 • 1,076 citations

Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular Degeneration

1997 • 861 citations

THE FRAMINGHAM EYE STUDY

1977 • 772 citations

Inhibition of Vascular Endothelial Growth Factor Prevents Retinal Ischemia—Associated Iris Neovascularization in a Nonhuman Primate

1996 • 638 citations

Transdifferentiated Retinal Pigment Epithelial Cells are Immunoreactive for Vascular Endothelial Growth Factor in Surgically Excised AgeRelated Macular Degeneration-Related Choroidal Neovascular Membranes.

1998 • 590 citations

Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis on a primate model

1994 • 584 citations

Intravitreous Injections of Vascular Endothelial Growth Factor Produce Retinal Ischemia and Microangiopathy in an Adult Primate

1996 • 516 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

1995 • 466 citations

VEGF is major stimulator in model of choroidal neovascularization.

2000 • 430 citations

Mechanism of Action of Biological Antioxidants

1992 • 391 citations

Transgenic Mice with Increased Expression of Vascular Endothelial Growth Factor in the Retina: A New Model of Intraretinal and Subretinal Neovascularization.

1998 • 367 citations

Targeted Disruption of the FGF2 Gene Does Not Prevent Choroidal Neovascularization in a Murine Model

1998 • 324 citations

Foveolar choroidal blood flow in age-related macular degeneration.

1998 • 317 citations

The Radicals in Cigarette Tar: Their Nature and Suggested Physiological Implications

1983 • 313 citations

Familial Aggregation of Age-related Maculopathy

1998 • 303 citations

The γ e4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration

1998 • 294 citations

The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration

2000 • 218 citations

A Twin Study of Age-related Macular Degeneration

1995 • 212 citations

Five-Year Incidence and Disappearance of Drusen and Retinal Pigment Epithelial Abnormalities

1995 • 211 citations

Gender, oestrogen, hormone replacement and age‐related macular degeneration: Results from the Blue Mountains Eye Study

1997 • 186 citations

Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase Inhibitor

1999 • 171 citations

Choroidal neovascularization in the rat induced by adenovirus mediated expression of vascular endothelial growth factor.

2000 • 124 citations

Expressions of angiopoietins and Tie2 in human choroidal neovascular membranes.

1999 • 121 citations

Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration

2000 • 103 citations

Pulsatile ocular blood flow study: decreases in exudative age related macular degeneration

2001 • 93 citations

Foveal electroretinograms and choroidal perfusion characteristics in fellow eyes of patients with unilateral neovascular age-related macular degeneration.

1995 • 84 citations

The Effect of Cigarette Smoking on the Intraocular Circulation

1958 • 41 citations