Signaling and Regulation by a Mammalian Glucocorticoid Receptor inDrosophilaCells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Cell lines derived from late embryonic stages of Drosophila melanogaster

1972 • 1,215 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

1988 • 705 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection

1988 • 547 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells

1986 • 408 citations

The human oestrogen receptor functions in yeast

1988 • 402 citations

Relation of steroid structure to enzyme induction in hepatoma tissue culture cells

1970 • 399 citations

jun:Oncogene and Transcription Factor

1990 • 337 citations

Mammalian Glucocorticoid Receptor Derivatives Enhance Transcription in Yeast

1988 • 315 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

In vitro transcription of the Drosophila engrailed gene.

1988 • 284 citations

An ecdysone response element in the Drosophila hsp27 promoter

1987 • 268 citations

Signal Transduction and Transcriptional Regulation by Glucocorticoid Receptor-LexA Fusion Proteins

1988 • 268 citations

A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable

1988 • 263 citations

Glucocorticoid Receptor Mutants That Define a Small Region Sufficient for Enhancer Activation

1987 • 260 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities.

1989 • 240 citations

Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4

1988 • 237 citations

Patterns of puffing activity in the salivary gland chromosomes of Drosophila

1972 • 231 citations

[26] Vectors for constitutive and inducible gene expression in yeast

1991 • 230 citations

Characterization of drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene

1985 • 229 citations

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site

1988 • 217 citations

Dynamic interaction between a Drosophila transcription factor and RNA polymerase II.

1989 • 191 citations

Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression.

1989 • 154 citations

Assembly and disassembly of the Drosophila RNA polymerase II complex during transcription.

1990 • 134 citations

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.

1987 • 125 citations

Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.

1988 • 124 citations

Zeste encodes a sequence-specific transcription factor that activates the Ultrabithorax promoter in vitro

1988 • 121 citations

In Vitro Transcription Enhancement by Purified Derivatives of the Glucocorticoid Receptor

1989 • 107 citations

Pro‐opiomelanocortin gene: A model for negative regulation of transcription by glucocorticoids

1987 • 104 citations

Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.

1987 • 103 citations

Fractionation of the general RNA polymerase II transcription factors from Drosophila embryos.

1990 • 90 citations

A single DNA-binding transcription factor is sufficient for activation from a distant enhancer and/or from a promoter position.

1990 • 88 citations

Purified Drosophila transcription factor, Adh distal factor-1 (Adf-1), binds to sites in several Drosophila promoters and activates transcription.

1990 • 60 citations