Human αB-crystallin gene and preferential promoter function in lens

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

1982 • 792 citations

LENS CRYSTALLINS: THE EVOLUTION AND EXPRESSION OF PROTEINS FOR A HIGHLY SPECIALIZED TISSUE

1988 • 770 citations

LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA

1968 • 706 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.

1983 • 546 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

The Vertebrate Eye Lens

1977 • 449 citations

Enzyme/crystallins: Gene sharing as an evolutionary strategy

1989 • 403 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

The Lens: Development, Proteins, Metabolism and Cataract

1984 • 342 citations

The Amino‐Acid Sequence of the αA₂ Chain of Bovine α‐Crystallin

1973 • 304 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library.

1988 • 286 citations

U6 small nuclear RNA is transcribed by RNA polymerase III.

1986 • 250 citations

Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

1985 • 242 citations

A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter

1989 • 237 citations

Evolution of eye lens crystallins: the stress connection

1989 • 209 citations

The Amino‐Acid Sequence of the αB₂ Chain of Bovine α‐Crystallin

1974 • 182 citations

Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used.

1988 • 157 citations

Complete structure of the alpha B-crystallin gene: conservation of the exon-intron distribution in the two nonlinked alpha-crystallin genes.

1985 • 130 citations

Sequence and expression of a major egg antigen from Schistosoma mansoni. Homologies to heat shock proteins and alpha-crystallins

1986 • 112 citations

Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells

1986 • 107 citations

Sequence of the chicken delta 2 crystallin gene and its intergenic spacer. Extreme homology with the delta 1 crystallin gene.

1986 • 87 citations

Regulation of the murine αA-crystallin promoter in transgenic mice

1990 • 82 citations

Evidence for positive and negative regulation in the promoter of the chicken δ1-crystallin gene

1988 • 81 citations

Complete structure of the hamster αA crystallin gene

1985 • 75 citations

Processed pseudogenes for rat cytochrome c are preferentially derived from one of three alternate mRNAs.

1984 • 73 citations

RABBIT CELLS SUSCEPTIBLE TO RUBELLA VIRUS

1963 • 67 citations

G-6-PD and PGM Phenotypes of 16 Continuous Human Tumor Cell Lines

1971 • 51 citations

Muscle-specific gene expression controlled by a regulatory element lacking a MyoDl-binding site

1989 • 47 citations

Transcriptional activation of heat-shock genes in eukaryotes

1988 • 47 citations

A pseudo-exon in the functional humanαA-crystallin gene

1989 • 45 citations

Alternative splicing of alpha A-crystallin RNA. Structural and quantitative analyses of the mRNAs for the alpha A2- and alpha Ains-crystallin polypeptides.

1984 • 43 citations

The primary structure of the B₂ chain of human α‐crystallin

1977 • 42 citations

Assignment of the αB-crystallin gene to human chromosome 11

1989 • 38 citations

Monoclonal antibodies reveal evolutionary conservation of alternative splicing of the αA‐crystallin primary transcript

1988 • 27 citations

Comparison of the crystallin mRNA populations from rat, calf and duck lens. Evidence for a longer αA2-mRNA and two distinct αB2-mRNAs in the birds

1985 • 10 citations