Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons

1975 • 1,073 citations

Substance P: Localization in the Central Nervous System and in Some Primary Sensory Neurons

1975 • 1,029 citations

Opiate analgesics inhibit substance P release from rat trigeminal nucleus

1977 • 968 citations

Multiple opiate receptor sites on primary afferent fibres

1980 • 621 citations

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

1983 • 582 citations

Progress in Clinical and Biological Research

1989 • 568 citations

Opiate Receptor Binding of Agonists and Antagonists Affected Differentially by Sodium

1974 • 554 citations

Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration.

1979 • 546 citations

The binding spectrum of narcotic analgesic drugs with different agonist and antagonist properties

1982 • 509 citations

The classification of drugs and drug receptors in isolated tissues.

1984 • 474 citations

Classification of multiple morphine and enkephalin binding sites in the central nervous system.

1981 • 372 citations

Release of substance P from the cat spinal cord.

1987 • 371 citations

Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat

1983 • 333 citations

Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.

1977 • 299 citations

Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture

1989 • 217 citations

Immunohistochemical localization of leucine‐enkephalin in the spinal cord of the cat: Enkephalin‐containing marginal neurons and pain modulation

1981 • 215 citations

Multiple opiate receptors: Differential binding of μ, κ and δ agonists

1981 • 201 citations

Specificity of opioids towards the μ-, δ- and ϵ-opiate receptors

1979 • 194 citations

Characterization of opioid receptors in nervous tissue

1980 • 172 citations

Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance

1983 • 151 citations

Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones

1979 • 134 citations

Opposite Effects of δ and μ Opioid Receptor Agonists on the In Vitro Release of Substance P‐Like Material from the Rat Spinal Cord

1987 • 99 citations

Morphine and norepinephrine but not 5-hydroxytryptamine and γ-aminobutyric acid inhibit the potassium-stimulated release of substance P from rat spinal cord slices

1986 • 99 citations

Different G proteins mediate the opioid inhibition or enhancement of evoked [5-methionine]enkephalin release.

1991 • 81 citations

Proglumide prevents and curtails acute tolerance to morphine in rats

1984 • 80 citations

Sufentanil, Morphine, Met-enkephalin, and k-Agonist (U-50,488H) Inhibit Substance P Release from Primary Sensory Neurons

1989 • 69 citations

Inhibitor of cyclic AMP-dependent protein kinase blocks opioid-induced prolongation of the action potential of mouse sensory ganglion neurons in dissociated cell cultures

1988 • 64 citations

Distinct Subtypes of the Opioid Receptor with Allosteric Interactions in Brain Membranes

1986 • 63 citations

Opioids can enhance and inhibit the electrically evoked release of methionine-enkephalin

1989 • 61 citations

Selectivity of ligand binding to opioid receptors in brain membranes from the rat, monkey and guinea pig

1988 • 58 citations

The μ, κ and δ properties of various opioid agonists

1986 • 50 citations

Neonatal capsaicin treatment abolishes the modulations by opioids of substance P release from rat spinal cord slices

1989 • 43 citations

Pre- and postsynaptic location of mu, delta and kappa opioid receptors in the superficial layers of the dorsal horn of the rat spinal cord.

1990 • 42 citations

Direct analysis of the release of methionine-enkephalin from guinea pig myenteric plexus: modulation by endogenous opioids and exogenous morphine.

1986 • 40 citations

The relationship of α-adrenoceptor reserve and agonist intrinsic efficacy to calcium utilization in the vasculature

1988 • 40 citations

Lack of evidence for ε-opioid receptors in the rat vas deferens

1988 • 18 citations