Opposite Effects of δ and μ Opioid Receptor Agonists on the In Vitro Release of Substance P‐Like Material from the Rat Spinal Cord

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Opiate analgesics inhibit substance P release from rat trigeminal nucleus

1977 • 968 citations

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

1983 • 737 citations

Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo

1980 • 697 citations

Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section

1976 • 642 citations

Multiple opiate receptor sites on primary afferent fibres

1980 • 621 citations

The binding spectrum of narcotic analgesic drugs with different agonist and antagonist properties

1982 • 509 citations

Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.

1984 • 417 citations

Substance P release from spinal cord slices by capsaicin

1979 • 376 citations

Effect of substance P in cat dorsal horn neurones activated by noxious stimuli

1977 • 362 citations

SPECTRUM OF THE μ‐, δ‐ AND κ‐BINDING SITES IN HOMOGENATES OF RAT BRAIN

1982 • 278 citations

Involvement of cholinergic presynaptic receptors of nicotinic and muscarinic types in the control of the spontaneous release of dopamine from striatal dopaminergic terminals in the rat.

1977 • 237 citations

Pharmacological characterization of substance P-induced nociception in mice: modulation by opioid and noradrenergic agonists at the spinal level.

1983 • 193 citations

Differential effects of morphine on responses of dorsal horn lamina V type cells elicited by A and C fibre stimulation in the spinal cat

1976 • 185 citations

Selective antagonists at the opiate delta-receptor

1982 • 170 citations

Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: A new highly potent and fully specific agonist for opiate δ-receptors

1983 • 169 citations

Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains

1983 • 148 citations

Opioid control of the function of primary afferent substance P fibres

1985 • 139 citations

Regional distribution of neuromedin K and neuromedin L in rat brain and spinal cord

1984 • 136 citations

Indirect evidence for presynaptic location of opiate receptors on chemosensitive primary sensory neurones

1979 • 134 citations

Effects of morphine on noxious stimuli-induced release of substance P from rabbit dorsal horn

1983 • 101 citations

The direction of opioid agonists towards μ-, δ- and ε-receptors in the vas deferens of the mouse and the rat

1980 • 99 citations

The case for multiple opiate receptors

1984 • 96 citations

Neuropeptides in sensory neurons

1982 • 91 citations

Characterization of the hyperalgesic effect induced by intrathecal injection of substance P

1985 • 89 citations

Met-enkephalin and morphine but not dynorphin inhibit noxious stimuli-induced release of substance P from rabbit dorsal horn in situ

1985 • 88 citations

Spinal and supraspinal opioid analgesia in the mouse: the role of subpopulations of opioid binding sites

1983 • 85 citations

Basic and Regulatory Mechanisms of In Vitro Release of Met‐Enkephalin from the Dorsal Zone of the Rat Spinal Cord

1984 • 83 citations

Multiple endogenous ligands for opioid receptors

1983 • 73 citations

Comparison of mu, delta, and kappa opiate binding sites in rat brain and spinal cord

1984 • 56 citations

In vivo release of substance P in the cat substantia nigra

1979 • 46 citations

Inhibitory effects of GABA, L-glutamic acid and nicotine on the potassium-evoked release of subsaance P in substantia nigra slices of the rat

1981 • 45 citations

Demonstration and Distribution of Kassinin‐Like Material (Substance K) in the Rat Central Nervous System

1985 • 44 citations

Lack of effect of baclofen on substance P and somatostatin release from the spinal cord in vitro

1982 • 31 citations

Opposite effects of the δ- and μ-opioid receptor agonists on ventilation in conscious adult dogs

1984 • 28 citations

Opiate binding in the rat spinal cord: Evidence for mu and delta sites

1984 • 18 citations

Studies on the opiate receptor-mediated inhibition of K+-stimulated cholecystokinin and substance P release from cat hypothalamus in vitro

1984 • 17 citations

Mechanism of action of cholecystokinin on intestinal blood flow; Interactions with opioid peptides and vasoactive intestinal peptide

1985 • 6 citations