PDGF and TGF-β contribute to the natural course of human IgA glomerulonephritis

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Quantitation of mRNA by the polymerase chain reaction.

1989 • 1,648 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

The Commonest Glomerulonephritis in the World: IgA Nephropathy

1987 • 873 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.

1993 • 525 citations

Tenascin: cDNA cloning and induction by TGF-beta.

1988 • 453 citations

Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis

1994 • 413 citations

Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor.

1992 • 345 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

1991 • 293 citations

Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis

1985 • 286 citations

In situ production of TNF-α, IL-1β and IL-2R in ANCA-positive glomerulonephritis

1993 • 278 citations

Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat.

1986 • 262 citations

Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats.

1993 • 254 citations

Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys.

1993 • 249 citations

Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells.

1989 • 235 citations

A role for podocytes to counteract capillary wall distension

1994 • 215 citations

ELEVATED EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA AND PROTEOGLYCAN PRODUCTION IN EXPERIMENTAL GLOMERULONEPHRITIS

1990 • 196 citations

Mesangial cells express PDGF mRNAs and proliferate in response to PDGF

1988 • 191 citations

The role of podocytes in the development of glomerular sclerosis.

1994 • 155 citations

Platelet-derived growth factor expression in mesangial proliferative glomerulonephritis.

1991 • 154 citations

Regulation of mesangial cell growth by polypeptide mitogens. Inhibitory role of transforming growth factor beta.

1989 • 122 citations

Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.

1993 • 118 citations

Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells

1992 • 116 citations

PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys

1993 • 110 citations

Visceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain.

1993 • 107 citations

Expression of platelet-derived growth factor receptors in normal and diseased human kidney. An immunohistochemistry and in situ hybridization study.

1994 • 102 citations

Expression of Platelet‐Derived Growth Factor Receptors is Induced on Connective Tissue Cells During Chronic Synovial Inflammation

1988 • 94 citations

Effects of transforming growth factor-beta, transforming growth factor-alpha, and other growth factors on renal proximal tubule cells.

1991 • 88 citations

Tenascin is an important component of the glomerular extracellular matrix in normal and pathologic conditions

1994 • 57 citations

Temporal expression of autocrine growth factors corresponds to morphological features of mesangial proliferation in Habu snake venom-induced glomerulonephritis.

1993 • 53 citations

Migratory and proliferative effect of platelet‐derived growth factor in rabbit retinal endothelial cells: Evidence of an autocrine pathway of platelet‐derived growth factor

1994 • 52 citations

Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells

1993 • 43 citations

Increased mRNA encoding for transforming factor-β in CD4+ cells from patients with IgA nephropathy

1994 • 40 citations

Nephrotic Range Proteinuria – A Good Predictive Index of Disease in IgA Nephropathy?

1985 • 34 citations

Survey of oncogene and growth factor/receptor gene expression in cancer cells by intron-differential RNAPCR

1990 • 32 citations

Tissue culture of normal rat glomeruli: glycosaminoglycan biosynthesis by homogeneous epithelial and mesangial cell populations.

1980 • 30 citations

Detection of human papilloma virus (HPV) DNA in genital biopsy specimens by in situ hybridization with digoxigenin-labeled probes

1989 • 29 citations

Platelet-Derived Growth Factor Mesangial Deposits in Mesangial IgA Glomerulonephritis

1991 • 28 citations

Intraglomerular expressions of IL-1α and platelet-derived growth factor (PDGF-B) mRNA in experimental immune complex-mediated glomerulonephritis

1994 • 16 citations

Relationship between Serum IgA Levels and CD4 Subsets in IgA Nephropathy

1994 • 7 citations

The Pathology of IgA Nephropathy

1987 • 7 citations

Deleted Work

1955 • 0 citations