Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

1999 • 1,905 citations

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

1999 • 1,570 citations

Novel Signal Transduction Pathway Utilized by Extracellular HSP70

2002 • 1,483 citations

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

2002 • 1,028 citations

HSP70 as Endogenous Stimulus of the Toll/Interleukin-1 Receptor Signal Pathway

2002 • 949 citations

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation

2002 • 583 citations

Human Toll-like receptor 4 recognizes host-specific LPS modifications

2002 • 570 citations

Rapid Cycling of Lipid Raft Markers between the Cell Surface and Golgi Complex

2001 • 525 citations

Cutting Edge: Cell Surface Expression and Lipopolysaccharide Signaling Via the Toll-Like Receptor 4-MD-2 Complex on Mouse Peritoneal Macrophages

2000 • 473 citations

Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction

2002 • 452 citations

Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment.

1985 • 428 citations

A CD14-independent LPS receptor cluster

2001 • 422 citations

Endotoxin Contamination in Recombinant Human Heat Shock Protein 70 (Hsp70) Preparation Is Responsible for the Induction of Tumor Necrosis Factor α Release by Murine Macrophages

2002 • 399 citations

Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells.

1997 • 392 citations

Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae.

1996 • 384 citations

Expression of the Molecular Chaperone Hsp70 in Detergent-resistant Microdomains Correlates with Its Membrane Delivery and Release

2003 • 299 citations

Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction

2003 • 238 citations

Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide

1999 • 202 citations

Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses

2004 • 142 citations

Hsp70 plasma membrane expression on primary tumor biopsy material and bone marrow of leukemic patients

2000 • 140 citations

Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70

2002 • 134 citations

ATP and ADP Modulate a Cation Channel Formed by Hsc70 in Acidic Phospholipid Membranes

2000 • 118 citations

KDEL proteins are found on the surface of NG108-15 cells

1999 • 112 citations

Spontaneous apoptosis and expression of cell surface heat‐shock proteins in cultured EL‐4 lymphoma cells

1999 • 74 citations

CD55/decay accelerating factor is part of the lipopolysaccharide‐induced receptor complex

2003 • 49 citations

Ultrastructural localization of Hsp-72 examined with a new polyclonal antibody raised against the truncated variable domain of the heat shock protein

1999 • 46 citations

Interactions of bacterial lipopolysaccharide and peptidoglycan with a 70 kDa and an 80 kDa protein on the cell surface of CD14+ and CD14− cells

2001 • 31 citations