Enhanced Therapeutic Efficacy of Tumor RNA-Pulsed Dendritic Cells after Genetic Modification with Lymphotactin

Dendritic cells and the control of immunity

1998 • 14,345 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

1998 • 1,448 citations

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

1997 • 1,143 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo.

1996 • 922 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

Cationic liposome-mediated RNA transfection.

1989 • 804 citations

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

1996 • 804 citations

Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.

1996 • 746 citations

Lymphotactin: a Cytokine that Represents a New Class of Chemokine

1994 • 668 citations

Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.

1998 • 627 citations

Dendritic cells in the T‐cell areas of lymphoid organs

1997 • 572 citations

Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.

1996 • 561 citations

A dendritic-cell-derived C–C chemokine that preferentially attracts naive T cells

1997 • 532 citations

Cutting Edge: Differential Regulation of Chemokine Receptors During Dendritic Cell Maturation: A Model for Their Trafficking Properties

1998 • 486 citations

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors

1997 • 443 citations

Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors

1997 • 432 citations

Identification of Tyrosinase-related Protein 2 as a Tumor Rejection Antigen for the B16 Melanoma

1997 • 405 citations

Chemokines and T Lymphocytes

1998 • 403 citations

Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity

1997 • 390 citations

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.

1997 • 388 citations

Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes.

1995 • 372 citations

CCR6, a CC Chemokine Receptor that Interacts with Macrophage Inflammatory Protein 3α and Is Highly Expressed in Human Dendritic Cells

1997 • 362 citations

A comparison of gene transfer methods in human dendritic cells.

1997 • 315 citations

Dendritic Cells Retrovirally Transduced with a Model Antigen Gene Are Therapeutically Effective against Established Pulmonary Metastases

1997 • 309 citations

Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells

1997 • 289 citations

Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.

1997 • 256 citations

CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma

1994 • 254 citations

Molecular cloning and functional characterization of human lymphotactin.

1995 • 223 citations

Retroviral transduction of human dendritic cells with a tumor-associated antigen gene.

1996 • 218 citations

Combined chemokine and cytokine gene transfer enhances antitumor immunity

1996 • 215 citations

Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.

1997 • 215 citations

A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells

1995 • 214 citations

Lymphotactin is produced by NK cells and attracts both NK cells and T cells in vivo.

1997 • 191 citations

Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-alpha.

1998 • 179 citations

Identification of Single C Motif-1/Lymphotactin Receptor XCR1

1998 • 167 citations

Review: Gene-Modified Dendritic Cells for Use in Tumor Vaccines

2000 • 145 citations

Reduced Tumorigenicity and Augmented Leukocyte Infiltration After Monocyte Chemotactic Protein-3 (MCP-3) Gene Transfer: Perivascular Accumulation of Dendritic Cells in Peritumoral Tissue and Neutrophil Recruitment Within the Tumor

1998 • 125 citations

Autologous Human Monocyte-Derived Dendritic Cells Genetically Modified to Express Melanoma Antigens Elicit Primary Cytotoxic T Cell Responses In Vitro: Enhancement by Cotransfection of Genes Encoding the Th1-Biasing Cytokines IL-12 and IFN-α

1998 • 125 citations

Lymphotactin Gene-Modified Bone Marrow Dendritic Cells Act as More Potent Adjuvants for Peptide Delivery to Induce Specific Antitumor Immunity

1998 • 114 citations

RNA-transfected dendritic cells in cancer immunotherapy

2000 • 108 citations

Dendritic cells produce macrophage inflammatory protein-1 gamma, a new member of the CC chemokine family.

1996 • 89 citations

Retrovirally Transduced Human Dendritic Cells Express a Normal Phenotype and Potent T-Cell Stimulatory Capacity

1997 • 85 citations

Successful retroviral mediated transduction of a reporter gene in human dendritic cells: feasibility of therapy with gene-modified antigen presenting cells.

1997 • 77 citations

Human dendritic cell (DC)-based anti-infective therapy: engineering DCs to secrete functional IFN-gamma and IL-12.

1998 • 52 citations

Human Dendritic Cell (DC)-Based Anti-Infective Therapy: Engineering DCs to Secrete Functional IFN-γ and IL-12

1998 • 46 citations

Tumor-rejection antigens recognized by T lymphocytes

1993 • 45 citations

Dendritic cell‐based cancer immunotherapy: Potential for treatment of colorectal cancer?

2000 • 25 citations

Enhanced efficacy of combination of IL-2 gene and IL-6 gene-transfected tumor cells in the treatment of established metastatic tumors.

1996 • 24 citations

Enhanced antitumor effects of tumor antigen-pulsed dendritic cells by their transfection with GM-CSF gene

1997 • 8 citations