New Uses for Calcium Channel Blockers

Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle

1977 • 1,745 citations

Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.

1989 • 1,087 citations

Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem

1980 • 865 citations

Multiple-Drug Resistance in Human Cancer

1987 • 703 citations

Retardation of angiographic progression of coronary artery disease by nifedipine

1990 • 610 citations

HIV-1 Coat Protein Neurotoxicity Prevented by Calcium Channel Antagonists

1990 • 595 citations

The Role of Protein Kinase C in Transmembrane Signalling

1986 • 557 citations

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.

1987 • 425 citations

A Controlled Trial of Nimodipine in Acute Ischemic Stroke

1988 • 423 citations

A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis.

1990 • 352 citations

Cerebral Arterial Spasm

1979 • 309 citations

Flunarizine A Review of Its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Use

1984 • 239 citations

Peripheral neuropathy in primary Sjögren's syndrome

1989 • 225 citations

Effects of calcium antagonists on renal hemodynamics

1985 • 215 citations

A randomized clinical study of a calcium-entry blocker (lidoflazine) in the treatment of comatose survivors of cardiac arrest

1991 • 203 citations

The selective inhibition of serotonin-induced contractions of rabbit cerebral vascular smooth muscle by calcium-antagonistic dihydropyridines. An investigation of the mechanism of action of nimodipine.

1981 • 198 citations

Should Hypertension Be Treated After Acute Stroke?

1993 • 198 citations

Prevention of Radiocontrast-Media-Induced Nephrotoxicity by the Calcium Channel Blocker Nitrendipine: A Prospective Randomised Clinical Trial

1989 • 194 citations

Cardiovascular drug therapy

1965 • 166 citations

A Double‐blind Placebo‐controlled Prophylactic Study of Flunarizine (Sibelium®) in Migraine

1981 • 162 citations

Intracellular calcium ions in affective disorders: a review and an hypothesis.

1983 • 159 citations

Treatment of severe pregnancy‐associated hypertension with the calcium antagonist nifedipine

1984 • 155 citations

Nimodipine after resuscitation from out-of-hospital ventricular fibrillation. A placebo-controlled, double-blind, randomized trial

1990 • 134 citations

Clinical Effectiveness of Calcium Entry Blockers in Prophylactic Treatment of Migraine and Cluster Headaches

1983 • 133 citations

Ischemic brain injury: the importance of calcium, lipolytic activities, and free fatty acids.

1982 • 130 citations

Verapamil Prophylaxis of Migraine

1983 • 129 citations

Nimodipine, a New Calcium Antagonist, in the Prophylactic Treatment of Migraine

1983 • 127 citations

Ca++ antagonists and ACAT inhibitors promote cholesterol efflux from macrophages by different mechanisms. I. Characterization of cellular lipid metabolism.

1988 • 119 citations

Randomised Prospective Study on Renal Effects of Two Different Contrast Media in Humans: Protective Role of a Calcium Channel Blocker

1990 • 112 citations

Placebo-controlled trial of nimodipine in the treatment of acute ischemic cerebral infarction.

1990 • 111 citations

Dose-escalation study of intravenous nicardipine in patients with aneurysmal subarachnoid hemorrhage

1988 • 106 citations

Smooth muscle cell migration induced by inflammatory cell products and its inhibition by a potent calcium antagonist, nilvadipine

1988 • 106 citations

Pharmacology of Nimodipine

1988 • 106 citations

Verapamil in prophylactic therapy of migraine

1984 • 98 citations

Effects of Topical Application of a Calcium Antagonist (Nifedipine) on Feline Cortical Pial Microvasculature under Normal Conditions and in Focal Ischemia

1983 • 95 citations

Alternating hemiplegia of childhood

1993 • 85 citations

Intravenous prostacyclin in acute nonhemorrhagic stroke: a placebo-controlled double-blind trial.

1987 • 79 citations

Calcium Antagonists and Renal Protection

1992 • 79 citations

Calcium Antagonists and the Kidney

1989 • 79 citations

Mechanisms of relaxant action of nicardipine, a new Ca++-antagonist, on isolated dog cerebral and mesenteric arteries.

1983 • 68 citations

Efficacy and mechanism of action of a calcium channel blocker after global cerebral ischemia in rats.

1988 • 67 citations

Raynaud's phenomenon. An update.

1991 • 66 citations

Early treatment of ischemic stroke with a calcium antagonist.

1991 • 63 citations

Long-term effects of verapamil on aortic smooth muscle cells cultured in the presence of hypercholesterolemic serum.

1987 • 60 citations

Nifedipine for intractable hiccups

1990 • 57 citations

Immunohistochemical Determination of Calcium—Calmodulin Binding Predicts Neuronal Damage after Global Ischemia

1989 • 56 citations

Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects.

1987 • 55 citations

Nimodipine

1992 • 55 citations

Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin

1991 • 52 citations

Hypertension-accelerated atherogenesis in cholesterol-fed rabbits

1977 • 51 citations

Calcium Channel Antagonists and the Treatment of Migraine

1986 • 48 citations

Effects of calcium antagonists on renal hemodynamics and glomerular function.

1992 • 47 citations

Hemostatic Mechanisms and Metastasis

1984 • 47 citations

Use of calcium channel entry blockers in the treatment of cardiac arrhythmias.

1989 • 44 citations

Efficacy of Nimodipine in the Prophylaxis of Migraine

1985 • 43 citations

Nifedipine in the prophylaxis of classic migraine

1989 • 38 citations

Long-term effects of verapamil on aortic smooth muscle cells cultured in the presence of hypercholesterolemic serum.

1987 • 35 citations

Calcium Antagonists in Patients with Heart Failure

1991 • 34 citations

Do Calcium Antagonists Have a Place in the Treatment of Mood Disorders?

1991 • 34 citations

Abnormal renal responses to calcium entry blockade in normotensive offspring of hypertensive parents.

1988 • 31 citations

Calcium channel blockers and ischaemic heart disease: theoretical expectations and clinical experience

1991 • 30 citations

The clinical effect of felodipine and nifedipine in Raynaud's phenomenon

1989 • 28 citations

Neurological recovery after cardiac arrest: Clinical feasibility trial of calcium blockers

1985 • 28 citations

Basic Mechanisms Involved in the Protection of the Ischaemic Myocardium

1991 • 28 citations

The use of calcium channel blockers in obstetrics and gynecology; a review

1990 • 27 citations

Use of verapamil to enhance the antiproliferative activity of BCNU in human glioma cells: an in vitro and in vivo study

1990 • 26 citations

Randomized, double-blind, placebo-controlled trial of nimodipine in acute stroke

1991 • 24 citations

The effect of flunarizine on essential tremor

1991 • 24 citations

Effects of Low-Dose Nifedipine on a Cold Provocation Test in Patients with Raynaudʼs Disease

1990 • 23 citations

An Overview of the Role of Calcium Antagonists in the Treatment of Achalasia and Diffuse Oesophageal Spasm

1992 • 22 citations

Clinical and Experimental Evidence for a Role of Calcium Entry Blockers in the Treatment of Migraine

1988 • 20 citations

Calcium dependent modulation of fast axonal transport

1988 • 20 citations

Alternative Prophylactic Treatments to Lithium in Bipolar Disorders

1990 • 18 citations

Non-surgical treatment of achalasia.

1991 • 16 citations

Pharmacology of Calcium Antagonists: Clinical Relevance in Neurology

1990 • 15 citations

The Antiatherogenic Potential of Calcium Antagonists

1988 • 15 citations

Calcium Channel Blockers: Inhibitors of Tumor Cell-Platelet-Endothelial Cell Interactions

1984 • 11 citations

Functional daytime incontinence: pharmacological treatment.

1992 • 10 citations

Analysis of Factors Involved in the Tissue Selectivity of Calcium Antagonists

1992 • 9 citations

Calcium Antagonists and Dysmenorrhea

1988 • 7 citations

Rationale for treatment of cancer with calcium antagonists. A review.

1988 • 6 citations

Management of Acute Non-Q-Wave Myocardial Infarction

1991 • 4 citations

Calcium antagonists in the vasodilatory treatment of primary pulmonary hypertension.

1990 • 1 citations

Deleted Work

1955 • 0 citations