Ca++ antagonists and ACAT inhibitors promote cholesterol efflux from macrophages by different mechanisms. I. Characterization of cellular lipid metabolism.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Mechanisms of action of transmitters and other substances on smooth muscle.

1979 • 2,193 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

A new solid-state reagent to iodinate proteins

1982 • 893 citations

Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem

1980 • 865 citations

Suppression of atherogenesis in cholesterol-fed rabbit treated with nifedipine.

1981 • 437 citations

Subfractionation of human high density lipoproteins by heparin-Sepharose affinity chromatography.

1980 • 349 citations

History of calcium antagonists.

1983 • 318 citations

Interaction of high density lipoproteins with cholesteryl ester-laden macrophages: biochemical and morphological characterization of cell surface receptor binding, endocytosis and resecretion of high density lipoproteins by macrophages.

1985 • 245 citations

Verapamil suppresses atherosclerosis in cholesterol-fed rabbits

1983 • 198 citations

Suppression of experimental atherosclerosis by the Ca++-antagonist lanthanum. Possible role of calcium in atherogenesis.

1980 • 187 citations

Atherosclerosis: Prevention by Agents Not Affecting Abnormal Levels of Blood Lipids

1981 • 182 citations

Radioimmunoassay studies of human apolipoprotein E.

1980 • 179 citations

Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells.

1982 • 170 citations

Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells.

1983 • 145 citations

Antiatherosclerotic effects of nicardipine and nifedipine in cholesterol-fed rabbits.

1985 • 141 citations

The effect of various centrally active drugs on adenosine uptake by the central nervous system

1982 • 138 citations

Regulation of high density lipoprotein receptors in cultured macrophages: role of acyl-CoA:cholesterol acyltransferase.

1985 • 137 citations

High-pressure liquid chromatography

1978 • 137 citations

Calcium antagonists suppress atherogenesis in aorta but not in the intramural coronary arteries of cholesterol-fed rabbits.

1983 • 134 citations

Mechanism of protection from atherosclerosis by verapamil in the cholesterol-fed rabbit

1984 • 133 citations

Verapamil enhances receptor-mediated endocytosis of low density lipoproteins by aortic cells in culture.

1985 • 120 citations

Neutral cholesterol esterase activity in macrophages and its enhancement by cAMP-dependent protein kinase.

1981 • 114 citations

Nifedipine increases cholesteryl ester hydrolytic activity in lipid-laden rabbit arterial smooth muscle cells. A possible mechanism for its antiatherogenic effect.

1985 • 113 citations

The effect of agents interfering with soft tissue calcification and cell proliferation on calcific fibrous-fatty plaques in rabbits.

1978 • 108 citations

Atherosclerosis, calcium, and calcium antagonists.

1985 • 106 citations

A quantitative densitometric method for the rapid separation and quantitation of the major tissue and lipoprotein lipids by high-performance thin-layer chromatography

1984 • 99 citations

Uptake by central nervous tissues as a mechanism for the regulation of extracellular adenosine concentrations

1984 • 97 citations

Arterial neutral cholesteryl esterase. A hormone-sensitive enzyme distinct from lysosomal cholesteryl esterase.

1983 • 96 citations

No effect of nifedipine on atherogenesis in cholesterol-fed rabbits.

1984 • 82 citations

Effects of Anoxia on Cerebral Blood Flow in the Rat Brain: Evidence for a Role of Adenosine in Autoregulation

1984 • 79 citations

Does nifedipine suppress atherogenesis in WHHL rabbits?

1984 • 67 citations

Ca++ antagonists and ACAT inhibitors promote cholesterol efflux from macrophages by different mechanisms. II. Characterization of intracellular morphologic changes.

1988 • 65 citations

Effects of anticalcifying and antifibrobrotic drugs on pre-established atherosclerosis in the rabbit

1979 • 62 citations

Plaque reversal with MgEDTA in experimental atherosclerosis: Elastin and collagen metabolism

1967 • 59 citations

Effect of nitroglycerin and nifedipine on subendocardial perfusion in the presence of a flow-limiting coronary stenosis in the awake dog.

1982 • 59 citations

Do benzodiazepines bind at adenosine uptake sites in CNS?

1981 • 53 citations

Adenosine uptake sites in dog heart and brain; interaction with calcium antagonists

1984 • 52 citations

The cholesterol content of the human erythrocyte influences calcium influx through the channel

1984 • 51 citations

Stereospecific modulation of the calcium channel in human erythrocytes by cholesterol and its oxidized derivatives

1985 • 48 citations

CHANGES OF CYCLIC‐AMP AND CYCLIC‐AMP PHOSPHODIESTERASE IN THE PROGRESSION AND REGRESSION OF EXPERIMENTAL ATHEROSCLEROSIS

1976 • 47 citations

Ineffectiveness of Ca2+-Antagonists Nicardipine and Diltiazem on Experimental Atherosclerosis in Cholesterol-fed Rabbits

1984 • 46 citations

Topography and dynamics of receptors for acetylated and malondialdehyde-modified low-density lipoprotein in the plasma membrane of mouse peritoneal macrophages as visualized by colloidal gold in conjunction with surface replicas.

1984 • 44 citations

[3H]Nitrobenzylthioinosine Binding to the Guinea Pig CNS Nucleoside Transport System: A Pharmacological Characterization

1984 • 44 citations

Regulation of neutral cholesteryl esterase in arterial smooth muscle cells: Stimulation by agonists of adenylate cyclase and cyclic AMP-dependent protein kinase

1986 • 41 citations

Activation of adrenal Sterol Ester Hydrolase by dibutyryl cAMP and protein kinase

1974 • 35 citations

Nifedipine: More than a calcium channel blocker

1986 • 30 citations

Enhancement of cholesteryl ester metabolism in cultured human monocyte-derived macrophages by verapamil

1985 • 29 citations

Interactions between adenosine and nifedipine in the rat cerebral cortex

1984 • 26 citations

Coronary interactions between nifedipine and adenosine in the intact dog heart

1982 • 25 citations

A quantitative densitometric method for the rapid separation and quantitation of the major lipids of tissues and lipoproteins by high-performance thin-layer chromatography

1984 • 20 citations

Cell density dependent uptake of LDL in cultured rat hepatocytes

1985 • 19 citations

Adenosine receptors in the heart: controversy about signal transmission

1985 • 16 citations

Calcium antagonists and the suppression of atherosclerosis

1984 • 16 citations

Adenosine and adenosine analogs inhibit phosphodiesterase activity in the heart

1984 • 15 citations

Pulmonary surfactant: its isolation, characterization and function

1985 • 12 citations

Slow channel kinetics in heart muscle

1981 • 5 citations

LDL-Binding to Human Liver Plasma Membranes

1986 • 1 citations